Synthesis and antiviral activity of scopadulcic acids analogues
ABSTRACT: The synthesis and antiviral properties of several scopadulcic acid analogues functionalized at C-6/C-7 and C-13 is reported. The preparation of advanced intermediates for the synthesis of scopadulcic acid B/scopadulciol analogues is also described. The biological study revealed the importa...
- Autores:
-
Betancur Galvis, Liliana Amparo
Bueno Sánchez, Juan Gabriel
Arnó, Manuel
González, Miguel Ángel
Zaragoza ́, Ramón
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2003
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/45278
- Acceso en línea:
- https://hdl.handle.net/10495/45278
- Palabra clave:
- Antivirales
Antiviral Agents
Scoparia
https://id.nlm.nih.gov/mesh/D000998
https://id.nlm.nih.gov/mesh/D036721
- Rights
- openAccess
- License
- Derechos reservados - Está prohibida la reproducción parcial o total de esta publicación
| Summary: | ABSTRACT: The synthesis and antiviral properties of several scopadulcic acid analogues functionalized at C-6/C-7 and C-13 is reported. The preparation of advanced intermediates for the synthesis of scopadulcic acid B/scopadulciol analogues is also described. The biological study revealed the importance of polar groups at C-13, while the stereochemistry at C-8 was not critical for activity. |
|---|