IgG4-related Disease : A Concise Review of the Current Literature

ABSTRACT: IgG4-related disease is the term used to refer to a condition characterized by a lymphoplasmacytic infiltrate, fibrosis and an increased number of IgG4+ cells present in tissue, in most cases, with an elevated serum IgG4 level. This disease frequently affects the pancreas, salivary glands...

Full description

Autores:
Ardila Suárez, Oscar
Gómez Puerta, José Alfredo
Andy, Abril
Tipo de recurso:
Review article
Fecha de publicación:
2017
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
spa
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/29759
Acceso en línea:
https://hdl.handle.net/10495/29759
Palabra clave:
Pancreatitis Autoinmune
Autoimmune pancreatitis
Enfermedad de Mikulicz
Mikulicz' Disease
Enfermedad Relacionada con Inmunoglobulina G4
Immunoglobulin G4-Related Disease
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.title.spa.fl_str_mv IgG4-related Disease : A Concise Review of the Current Literature
dc.title.translated.spa.fl_str_mv Enfermedad relacionada con IgG4 : revisión concisa de la literatura
title IgG4-related Disease : A Concise Review of the Current Literature
spellingShingle IgG4-related Disease : A Concise Review of the Current Literature
Pancreatitis Autoinmune
Autoimmune pancreatitis
Enfermedad de Mikulicz
Mikulicz' Disease
Enfermedad Relacionada con Inmunoglobulina G4
Immunoglobulin G4-Related Disease
title_short IgG4-related Disease : A Concise Review of the Current Literature
title_full IgG4-related Disease : A Concise Review of the Current Literature
title_fullStr IgG4-related Disease : A Concise Review of the Current Literature
title_full_unstemmed IgG4-related Disease : A Concise Review of the Current Literature
title_sort IgG4-related Disease : A Concise Review of the Current Literature
dc.creator.fl_str_mv Ardila Suárez, Oscar
Gómez Puerta, José Alfredo
Andy, Abril
dc.contributor.author.none.fl_str_mv Ardila Suárez, Oscar
Gómez Puerta, José Alfredo
Andy, Abril
dc.contributor.researchgroup.spa.fl_str_mv Grupo de Reumatología Universidad de Antioquia -GRUA-
dc.subject.decs.none.fl_str_mv Pancreatitis Autoinmune
Autoimmune pancreatitis
Enfermedad de Mikulicz
Mikulicz' Disease
Enfermedad Relacionada con Inmunoglobulina G4
Immunoglobulin G4-Related Disease
topic Pancreatitis Autoinmune
Autoimmune pancreatitis
Enfermedad de Mikulicz
Mikulicz' Disease
Enfermedad Relacionada con Inmunoglobulina G4
Immunoglobulin G4-Related Disease
description ABSTRACT: IgG4-related disease is the term used to refer to a condition characterized by a lymphoplasmacytic infiltrate, fibrosis and an increased number of IgG4+ cells present in tissue, in most cases, with an elevated serum IgG4 level. This disease frequently affects the pancreas, salivary glands and lymph nodes, but can involve almost any tissue. Its etiology and the exact role of the different inflammatory cells in the damage to the target organ is still unclear. As yet, there is no international consensus about diagnostic criteria for the disease, but there are important advances in its treatment and in the quest to achieve remission. We include a review of the history, possible pathogenesis, clinical manifestations, diagnostic approach and available therapeutic approaches.
publishDate 2017
dc.date.issued.none.fl_str_mv 2017
dc.date.accessioned.none.fl_str_mv 2022-07-15T21:57:39Z
dc.date.available.none.fl_str_mv 2022-07-15T21:57:39Z
dc.type.spa.fl_str_mv Artículo de revisión
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dc.identifier.citation.spa.fl_str_mv Ardila-Suarez O, Abril A, Gómez-Puerta JA. IgG4-related disease: A concise review of the current literature. Reumatol Clin. 2017 May-Jun;13(3):160-166. English, Spanish. doi: 10.1016/j.reuma.2016.05.009.
dc.identifier.issn.none.fl_str_mv 1699-258X
1885-1398
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10495/29759
dc.identifier.doi.none.fl_str_mv 10.1016/j.reumae.2016.05.006
10.1016/j.reuma.2016.05.009
identifier_str_mv Ardila-Suarez O, Abril A, Gómez-Puerta JA. IgG4-related disease: A concise review of the current literature. Reumatol Clin. 2017 May-Jun;13(3):160-166. English, Spanish. doi: 10.1016/j.reuma.2016.05.009.
1699-258X
1885-1398
10.1016/j.reumae.2016.05.006
10.1016/j.reuma.2016.05.009
url https://hdl.handle.net/10495/29759
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dc.relation.ispartofjournal.spa.fl_str_mv Reumatología Clínica
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Colegio Mexicano de Reumatología
Elsevier
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spelling Ardila Suárez, OscarGómez Puerta, José AlfredoAndy, AbrilGrupo de Reumatología Universidad de Antioquia -GRUA-2022-07-15T21:57:39Z2022-07-15T21:57:39Z2017Ardila-Suarez O, Abril A, Gómez-Puerta JA. IgG4-related disease: A concise review of the current literature. Reumatol Clin. 2017 May-Jun;13(3):160-166. English, Spanish. doi: 10.1016/j.reuma.2016.05.009.1699-258X1885-1398https://hdl.handle.net/10495/2975910.1016/j.reumae.2016.05.00610.1016/j.reuma.2016.05.009ABSTRACT: IgG4-related disease is the term used to refer to a condition characterized by a lymphoplasmacytic infiltrate, fibrosis and an increased number of IgG4+ cells present in tissue, in most cases, with an elevated serum IgG4 level. This disease frequently affects the pancreas, salivary glands and lymph nodes, but can involve almost any tissue. Its etiology and the exact role of the different inflammatory cells in the damage to the target organ is still unclear. As yet, there is no international consensus about diagnostic criteria for the disease, but there are important advances in its treatment and in the quest to achieve remission. We include a review of the history, possible pathogenesis, clinical manifestations, diagnostic approach and available therapeutic approaches.RESUMEN: La enfermedad relacionada con IgG4 (ER-IgG4) es una entidad recientemente nominada para definir diversas enfermedades caracterizadas por infiltración linfoplasmocítica, fibrosis, presencia de un número aumentado de células IgG4+ y, en gran parte de los casos, niveles aumentados de IgG4 sérica, afectando frecuentemente el páncreas, las glándulas salivales y los ganglios linfáticos pero pudiendo comprometer casi cualquier estructura de la anatomía humana. Aunque su etiología se desconoce, se han realizado avances en el conocimiento de sus bases fisiopatológicas e inmunológicas, al igual que del rol de las células inflamatorias en el desarrollo de dano˜ del órgano blanco. No existe hasta la fecha un consenso internacional sobre su diagnóstico, lo que no ha impedido avances terapéuticos muy importantes en su control y búsqueda de remisión. Se hace una revisión acerca de la historia, hipótesis sobre la etiología de la enfermedad, sus manifestaciones clínicas, abordaje diagnóstico y terapéuticoCOL00109597application/pdfengspaSociedad Española de ReumatologíaColegio Mexicano de ReumatologíaElsevierBarcelona, Españahttp://creativecommons.org/licenses/by-nc-nd/2.5/co/https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2IgG4-related Disease : A Concise Review of the Current LiteratureEnfermedad relacionada con IgG4 : revisión concisa de la literaturaArtículo de revisiónhttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPancreatitis AutoinmuneAutoimmune pancreatitisEnfermedad de MikuliczMikulicz' DiseaseEnfermedad Relacionada con Inmunoglobulina G4Immunoglobulin G4-Related DiseaseReumatol. 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