Low Temperature Crystal Structure of Natural Diosgenone

ABSTRACT: The molecular structure of diosgenone, a natural steroidal sapogenin, closely related to diosgenin and isolated from Solanum nudum, was solved by single crystal X-ray diffractometry at 120 K and refined by full-matrix least-squares to an agreement factor, R1 = 0.054. It crystallizes in the monoclinic space group P2(1), with a = 15.1870(4) A, b = 7.2710(2) A, c = 21.2840(6) A, beta = 99.251(1) degrees, and four molecules in the unit cell (Z = 4). The results constitute the first structural report on a steroidal sapogenin from the diosgenin group.

• Autores: Tobón Zapata, Gloria Elena; Baran, Enrique J.; Piro, Oscar E.; Castellano, Eduardo E.; Blair Trujillo, Silvia
• Tipo de recurso: Article of journal
• Fecha de publicación: 2002
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/35962
• Acceso en línea: https://hdl.handle.net/10495/35962
• Palabra clave: Cristalografía por Rayos X - métodos; Crystallography, X-Ray - methods; Congelación; Freezing; Conformación Molecular; Molecular Conformation; Sapogeninas - aislamiento and purificación; Sapogenins - isolation and purification; Compuestos de Espiro - química; Spiro Compounds - chemistry; Compuestos de Espiro - aislamiento and purificación; Spiro Compounds - isolation and purification; Triterpenos - aislamiento and purificación; Triterpenes - isolation and purification; Difracción de Rayos X - métodos; X-Ray Diffraction - methods
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc-nd/2.5/co/