Systematic review of microeconomic analysis of pregnancy-associated malaria

ABSTRACT : Introduction: Pregnancy-associated malaria (PAM) is a health problem with serious clinical, epidemiological and economic effects. Purpose: To analyze the microeconomic evaluations of PAM reported in the world scientific literature. Methods: Systematic review with 15 different search strategies in PubMed, ScienceDirect, Scielo, Google Scholar and Malaria in Pregnancy (MiP) Library. A search, selection and extraction protocol was applied, which guaranteed completeness and reproducibility in accordance with preferred reporting items for systematic reviews and meta-analysis guidelines. The methodological quality was evaluated using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) guide. The analysis were based on frequencies, costs and average and incremental cost-effectiveness ratios in 2018 US dollars adjusted for purchasing power parity. Results: Twenty-two evaluations published between 1990 and 2018 were analyzed, of which 82% addressed costeffectiveness in Africa. Twelve interventions were studied; of these, intermittent preventive treatment in pregnant women with sulfadoxine-pyrimethamine (IPTp-SP) was the most frequent strategy. The main outcomes were low birth weight, anaemia and DALYs avoided. The best average cost-effectiveness ratio was reported in IPTp-SP with a cost of US$ 2 per DALY avoided, followed by the administration of IPTp-SP in pregnant women with HIV (US$ 14.2). Conclusions: The studies focus on Africa with a high heterogeneity in the interventions, outcomes, resources and populations studied. All the interventions were highly cost-effective, which demonstrates the importance of including prevention, care and control resources for PAM as a priority in health sector budgets. This is especially true considering the importance of its intervention for social progress and overcoming poverty in endemic areas.

• Autores: Restrepo Posada, Deisy Cristina; Carmona Fonseca, Jaime; Cardona Arias, Jaiberth Antonio
• Tipo de recurso: Review article
• Fecha de publicación: 2020
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/31147
• Acceso en línea: https://hdl.handle.net/10495/31147
• Palabra clave: Malaria; Embarazo; Pregnancy; Salud de la Mujer; Women's Health; Enfermedades Transmisibles; Communicable Diseases; Medicina Basada en la Evidencia; Evidence-Based Medicine; Revisión Sistemática; Systematic Review; Evaluación económica; Economic evaluation
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc-nd/2.5/co/