Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas

ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpi...

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Autores:
Gómez Betancur, Isabel Cristina
Benjumea Gutiérrez, Dora María
Mejía, Natalia
León, Juan F.
Gómez, Juan E.
Tipo de recurso:
Article of investigation
Fecha de publicación:
2019
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/20250
Acceso en línea:
http://hdl.handle.net/10495/20250
Palabra clave:
Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.title.spa.fl_str_mv Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
spellingShingle Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
title_short Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_full Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_fullStr Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_full_unstemmed Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_sort Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
dc.creator.fl_str_mv Gómez Betancur, Isabel Cristina
Benjumea Gutiérrez, Dora María
Mejía, Natalia
León, Juan F.
Gómez, Juan E.
dc.contributor.author.none.fl_str_mv Gómez Betancur, Isabel Cristina
Benjumea Gutiérrez, Dora María
Mejía, Natalia
León, Juan F.
Gómez, Juan E.
dc.contributor.researchgroup.spa.fl_str_mv Toxinología Alternativas Terapéuticas y Alimentarias
dc.subject.agrovoc.none.fl_str_mv Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
topic Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
dc.subject.proposal.spa.fl_str_mv Renealmia alpinia
Antinociceptive
dc.subject.agrovocuri.none.fl_str_mv http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
description ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpinia leave-extracts have shown enzymatic inhibition of Bothrops atrox and Bothrops asper snake poison. The extracts also showed effects as a peripheral analgesic agent. This report investigates the analgesic activity of the essential oils obtained by hydrodistillation from wild and in vitro propagation samples of R. alpinia as well as the chemical profile using GC-MS. The essential oils isolated from R. alpinia evaluated on concentrations of 50, 75 and 100 mg/kg showed significant antinociceptive effects in the test of acetic-acid-induced abdominal writhing, compared to the control animals. The essential oil of the wild flora leaves showed the highest percentage of pain inhibition by 200 mg/kg, concluding that the essential oil of R. alpinia presents antinociceptive activity in an in vivo model. These results help us to understand the traditional use of R. alpinia to treat pain and make it a potential source for the development of phytopharmaceutics.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2021-06-22T22:34:27Z
dc.date.available.none.fl_str_mv 2021-06-22T22:34:27Z
dc.type.spa.fl_str_mv Artículo de investigación
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/20250
dc.identifier.doi.none.fl_str_mv 10.25135/rnp.70.18.01.084
dc.identifier.eissn.none.fl_str_mv 1307-6167
url http://hdl.handle.net/10495/20250
identifier_str_mv 10.25135/rnp.70.18.01.084
1307-6167
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Rec. Nat. Prod.
dc.relation.citationendpage.spa.fl_str_mv 17
dc.relation.citationissue.spa.fl_str_mv 1
dc.relation.citationstartpage.spa.fl_str_mv 10
dc.relation.citationvolume.spa.fl_str_mv 13
dc.relation.ispartofjournal.spa.fl_str_mv Records of Natural Products
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dc.publisher.place.spa.fl_str_mv Turquía
institution Universidad de Antioquia
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spelling Gómez Betancur, Isabel CristinaBenjumea Gutiérrez, Dora MaríaMejía, NataliaLeón, Juan F.Gómez, Juan E.Toxinología Alternativas Terapéuticas y Alimentarias2021-06-22T22:34:27Z2021-06-22T22:34:27Z2019http://hdl.handle.net/10495/2025010.25135/rnp.70.18.01.0841307-6167ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpinia leave-extracts have shown enzymatic inhibition of Bothrops atrox and Bothrops asper snake poison. The extracts also showed effects as a peripheral analgesic agent. This report investigates the analgesic activity of the essential oils obtained by hydrodistillation from wild and in vitro propagation samples of R. alpinia as well as the chemical profile using GC-MS. The essential oils isolated from R. alpinia evaluated on concentrations of 50, 75 and 100 mg/kg showed significant antinociceptive effects in the test of acetic-acid-induced abdominal writhing, compared to the control animals. The essential oil of the wild flora leaves showed the highest percentage of pain inhibition by 200 mg/kg, concluding that the essential oil of R. alpinia presents antinociceptive activity in an in vivo model. These results help us to understand the traditional use of R. alpinia to treat pain and make it a potential source for the development of phytopharmaceutics.COL00144768application/pdfengAcg Publishing Press ReleaseTurquíahttps://creativecommons.org/licenses/by-nc-nd/4.0/http://creativecommons.org/licenses/by-nc-nd/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) 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