First Molecular Detection and Epidemiological Analysis of Equine Influenza Virus in Two Regions of Colombia, 2020-2023

ABSTRACT: Equine influenza is a viral disease caused by the equine influenza virus (EIV), and according to the WOAH, it is mandatory to report these infections. In Latin America and Colombia, EIV risk factors have not been analyzed. The objective of this research is to perform an epidemiological and molecular analysis of the EIV in horses with respiratory symptoms from 2020 to 2023 in Colombia. Molecular EIV detection was performed using RT–qPCR and nanopore sequencing. A risk analysis was also performed via the GEE method. A total of 188 equines with EIV respiratory symptoms were recruited. The positivity rate was 33.5%. The descriptive analysis showed that only 12.8% of the horses were vaccinated, and measures such as the quarantine and isolation of symptomatic animals accounted for 91.5% and 88.8%, respectively. The variables associated with the EIV were the non-isolation of positive individuals (OR = 8.16, 95% CI (1.52–43.67), p = 0.014) and sharing space with poultry (OR = 2.16, 95% CI (1.09–4.26), p = 0.027). In conclusion, this is the first EIV investigation in symptomatic horses in Colombia, highlighting the presence of the virus in the country and the need to improve preventive and control measures.

• Autores: González Obando, Juliana; Zuluaga Cabrera, Angélica María; Forero Duarte, Jorge Eduardo; Úsuga, Jaime; Ciuderis, Karl; Moreno, Isabel; DÍaz, Andrés; Rojas Arbeláez, Carlos; Hernández Ortiz, Juan Pablo; Ruiz Sáenz, Julián
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2024
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/43395
• Acceso en línea: https://hdl.handle.net/10495/43395
• Palabra clave: Colombia - epidemiología; Colombia - epidemiology; Enfermedades de los Caballos; Horse Diseases; Caballos; Horses; Subtipo H3N8 del Virus de la Influenza A; Influenza A Virus, H3N8 Subtype; Secuenciación de Nanoporos; Nanopore Sequencing; Infecciones por Orthomyxoviridae; Orthomyxoviridae Infections; Filogenia; Phylogeny; Factores de Riesgo; Risk Factors; Patología Molecular; Pathology, Molecular; https://id.nlm.nih.gov/mesh/D003105; https://id.nlm.nih.gov/mesh/D006734; https://id.nlm.nih.gov/mesh/D006736; https://id.nlm.nih.gov/mesh/D053123; https://id.nlm.nih.gov/mesh/D000081414; https://id.nlm.nih.gov/mesh/D009976; https://id.nlm.nih.gov/mesh/D010802; https://id.nlm.nih.gov/mesh/D012307; https://id.nlm.nih.gov/mesh/D057089
• Rights: openAccess
• License: http://creativecommons.org/licenses/by/2.5/co/