The Alzheimer’s Prevention Initiative Autosomal-Dominant Alzheimer’s Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer’s disease, including a placebo-treated noncarrier cohort

ABSTRACT: Introduction: Autosomal-dominant Alzheimer's disease (ADAD) represents a crucial population for identifying prevention strategies that might modify disease course for cognitively unimpaired individuals at high imminent risk for developing symptoms due to Alzheimer's disease (AD),...

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Autores:

Lopera Restrepo, Francisco Javier
Ríos Romenets, Silvia
Giraldo Chica, Margarita María
Acosta Baena, Natalia
Tobón Quintero, Carlos Andrés
Ramos Pérez, Claudia Patricia
Langbaum, Jessica B.
Tariot, Pierre N.
Thomas, Ronald
Hendrix, Suzanne
Schneider, Lon S.
Espinosa, Alejandro
Cho, William
Ward, Michael
Clayton, David
Friesenhahn, Michael
Mackey, Howard
Honigberg, Lee
Sanabria Bohórquez, Sandra
Chen, Kewei
Walsh, Trisha
Langlois, Carolyn
Reiman, Eric M.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2018

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39586

Acceso en línea:

https://hdl.handle.net/10495/39586

Palabra clave:

Enfermedad de Alzheimer
Alzheimer Disease
Ensayo Clínico
Clinical Trial
Enfermedad de Alzheimer - prevención y control
Alzheimer Disease - prevention and control
https://id.nlm.nih.gov/mesh/D000544
https://id.nlm.nih.gov/mesh/D016430

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/