Genomic characterization of VIM Metallo-β-Lactamase-Producing alcaligenes faecalis from Gaza, Palestine

ABSTRACT : Carbapenemase-producing Gram-negative bacteria (CP-GNB) have increasingly spread worldwide, and different families of carbapenemases have been identified in various bacterial species. Here, we report the identification of five VIM metallo- -lactamase-producing Alcaligenes faecalis isolate...

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Autores:
Al Laham, Nahed
Chavda, Kalyan
Cienfuegos Gallet, Astrid Vanessa
Kreiswirth, Barry
Chen, Liang
Tipo de recurso:
Article of investigation
Fecha de publicación:
2017
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/20640
Acceso en línea:
http://hdl.handle.net/10495/20640
Palabra clave:
Alcaligenes faecalis
Bacterias Gramnegativas
Gram-Negative Bacteria
Genoma Bacteriano
Genome, Bacterial
metallo-β-lactamase
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/
Description
Summary:ABSTRACT : Carbapenemase-producing Gram-negative bacteria (CP-GNB) have increasingly spread worldwide, and different families of carbapenemases have been identified in various bacterial species. Here, we report the identification of five VIM metallo- -lactamase-producing Alcaligenes faecalis isolates associated with a small outbreak in a large hospital in Gaza, Palestine. Next-generation sequencing analysis showed blaVIM-2 is harbored by a chromosomal genomic island among three strains, while blaVIM-4 is carried by a novel plasmid in two strains.