Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline

ABSTRACT: Approximately 1.4 million women living with HIV become pregnant every year. Most women use antiretroviral therapy, to reduce the risk of vertical transmission or for personal health reasons. Using the GRADE framework according to the BMJ Rapid Recommendation process, we make recommendations for optimal choice of combination antiretroviral regimen considering patient values and preferences, the balance of desirable and undesirable outcomes, their uncertainty, and practical issues. We suggest a zidovudine and lamivudine-based regimen over one that includes tenofovir or emtricitabine (weak recommendation). We recommend alternatives over the combination of tenofovir, emtricitabine, and lopinavir/ritonavir (strong recommendation).

• Autores: Beltrán Arroyave, Claudia Patricia; Siemieniuk, Reed A C; Lytvyn, Lyubov; Ming, Jinell Mah; Mullen, Rhonda Marama; Anam, Florence; Otieno, Teresia; Guyatt, Gordon H.; Taylor, Graham P.; Okwen, Patrick Mbah; Nduati, Ruth; Kinuthia, John; Luma, Henry Namme; Kirpalani, Haresh; Merglen, Arnaud; Lesi, Olufunmilayo A.; Vandvik, Per Olav; Agoritsas, Thomas; Bewley, Susan
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2017
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/39083
• Acceso en línea: https://hdl.handle.net/10495/39083
• Palabra clave: Fármacos Anti-VIH; Anti-HIV Agents; Infecciones por VIH; HIV Infections; Transmisión Vertical de Enfermedad Infecciosa; Infectious Disease Transmission, Vertical; Complicaciones Infecciosas del Embarazo; Pregnancy Complications, Infectious; https://id.nlm.nih.gov/mesh/D019380; https://id.nlm.nih.gov/mesh/D015658; https://id.nlm.nih.gov/mesh/D018445; https://id.nlm.nih.gov/mesh/D011251
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc/2.5/co/