Multiple Independent Introductions of Plasmodium Falciparum in South America
ABSTRACT: The origin of Plasmodium falciparum in South America is controversial. Some studies suggest a recent introduction during the European colonizations and the transatlantic slave trade. Other evidence—archeological and genetic—suggests a much older origin. We collected and analyzed P. falcipa...
- Autores:
-
Yalcindag, Erhan
Elguero, Eric
Arnathau, Céline
Durand, Patrick
Akiana, Jean
Anderson, Timothy J
Aubouy, Agnes
Balloux, François
Besnard, Patrick
Bogreau, Hervé
Carnevale, Pierre
D'Alessandro, Umberto
Fontenille, Didier
Gamboa, Dionicia
Jombart, Thibaut
Le Mire, Jacques
Leroy, Eric
Maestre Buitrago, Amanda Elena
Mayxay, Mayfong
Ménard, Didier
Musset, Lise
Newton, Paul N.
Nkoghé, Dieudonné
Noya, Oscar
Ollomo, Benjamin
Rogier, Christophe
Veron, Vincent
Wide, Albina
Zakeri, Sedigheh
Carme, Bernard
Legrand, Eric
Chevillon, Christine
Ayala Pereda, Francisco José
Renaud, François
Prugnollea, Franck
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2012
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/34714
- Acceso en línea:
- https://hdl.handle.net/10495/34714
- Palabra clave:
- Human Migration
Migración Humana
Genetic Variation
Variación Genética
Malaria, Falciparum
Malaria Falciparum
Plasmodium Falciparum
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/
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| dc.title.spa.fl_str_mv |
Multiple Independent Introductions of Plasmodium Falciparum in South America |
| title |
Multiple Independent Introductions of Plasmodium Falciparum in South America |
| spellingShingle |
Multiple Independent Introductions of Plasmodium Falciparum in South America Human Migration Migración Humana Genetic Variation Variación Genética Malaria, Falciparum Malaria Falciparum Plasmodium Falciparum |
| title_short |
Multiple Independent Introductions of Plasmodium Falciparum in South America |
| title_full |
Multiple Independent Introductions of Plasmodium Falciparum in South America |
| title_fullStr |
Multiple Independent Introductions of Plasmodium Falciparum in South America |
| title_full_unstemmed |
Multiple Independent Introductions of Plasmodium Falciparum in South America |
| title_sort |
Multiple Independent Introductions of Plasmodium Falciparum in South America |
| dc.creator.fl_str_mv |
Yalcindag, Erhan Elguero, Eric Arnathau, Céline Durand, Patrick Akiana, Jean Anderson, Timothy J Aubouy, Agnes Balloux, François Besnard, Patrick Bogreau, Hervé Carnevale, Pierre D'Alessandro, Umberto Fontenille, Didier Gamboa, Dionicia Jombart, Thibaut Le Mire, Jacques Leroy, Eric Maestre Buitrago, Amanda Elena Mayxay, Mayfong Ménard, Didier Musset, Lise Newton, Paul N. Nkoghé, Dieudonné Noya, Oscar Ollomo, Benjamin Rogier, Christophe Veron, Vincent Wide, Albina Zakeri, Sedigheh Carme, Bernard Legrand, Eric Chevillon, Christine Ayala Pereda, Francisco José Renaud, François Prugnollea, Franck |
| dc.contributor.author.none.fl_str_mv |
Yalcindag, Erhan Elguero, Eric Arnathau, Céline Durand, Patrick Akiana, Jean Anderson, Timothy J Aubouy, Agnes Balloux, François Besnard, Patrick Bogreau, Hervé Carnevale, Pierre D'Alessandro, Umberto Fontenille, Didier Gamboa, Dionicia Jombart, Thibaut Le Mire, Jacques Leroy, Eric Maestre Buitrago, Amanda Elena Mayxay, Mayfong Ménard, Didier Musset, Lise Newton, Paul N. Nkoghé, Dieudonné Noya, Oscar Ollomo, Benjamin Rogier, Christophe Veron, Vincent Wide, Albina Zakeri, Sedigheh Carme, Bernard Legrand, Eric Chevillon, Christine Ayala Pereda, Francisco José Renaud, François Prugnollea, Franck |
| dc.contributor.researchgroup.spa.fl_str_mv |
Salud y Comunidad |
| dc.subject.decs.none.fl_str_mv |
Human Migration Migración Humana Genetic Variation Variación Genética Malaria, Falciparum Malaria Falciparum Plasmodium Falciparum |
| topic |
Human Migration Migración Humana Genetic Variation Variación Genética Malaria, Falciparum Malaria Falciparum Plasmodium Falciparum |
| description |
ABSTRACT: The origin of Plasmodium falciparum in South America is controversial. Some studies suggest a recent introduction during the European colonizations and the transatlantic slave trade. Other evidence—archeological and genetic—suggests a much older origin. We collected and analyzed P. falciparum isolates from different regions of the world, encompassing the distribution range of the parasite, including populations from sub-Saharan Africa, the Middle East, Southeast Asia, and South America. Analyses of microsatellite and SNP polymorphisms show that the populations of P. falciparum in South America are subdivided in two main genetic clusters (northern and southern). Phylogenetic analyses, as well as Approximate Bayesian Computation methods suggest independent introductions of the two clusters from African sources. Our estimates of divergence time between the South American populations and their likely sources favor a likely introduction from Africa during the transatlantic slave trade. |
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2012 |
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2012 |
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2023-04-18T16:46:05Z |
| dc.date.available.none.fl_str_mv |
2023-04-18T16:46:05Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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https://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Yalcindag E, Elguero E, Arnathau C, Durand P, Akiana J, Anderson TJ, Aubouy A, Balloux F, Besnard P, Bogreau H, Carnevale P, D'Alessandro U, Fontenille D, Gamboa D, Jombart T, Le Mire J, Leroy E, Maestre A, Mayxay M, Ménard D, Musset L, Newton PN, Nkoghé D, Noya O, Ollomo B, Rogier C, Veron V, Wide A, Zakeri S, Carme B, Legrand E, Chevillon C, Ayala FJ, Renaud F, Prugnolle F. Multiple independent introductions of Plasmodium falciparum in South America. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):511-6. doi: 10.1073/pnas.1119058109. |
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0027-8424 |
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https://hdl.handle.net/10495/34714 |
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10.1073/pnas.1119058109 |
| dc.identifier.eissn.none.fl_str_mv |
091-6490 |
| identifier_str_mv |
Yalcindag E, Elguero E, Arnathau C, Durand P, Akiana J, Anderson TJ, Aubouy A, Balloux F, Besnard P, Bogreau H, Carnevale P, D'Alessandro U, Fontenille D, Gamboa D, Jombart T, Le Mire J, Leroy E, Maestre A, Mayxay M, Ménard D, Musset L, Newton PN, Nkoghé D, Noya O, Ollomo B, Rogier C, Veron V, Wide A, Zakeri S, Carme B, Legrand E, Chevillon C, Ayala FJ, Renaud F, Prugnolle F. Multiple independent introductions of Plasmodium falciparum in South America. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):511-6. doi: 10.1073/pnas.1119058109. 0027-8424 10.1073/pnas.1119058109 091-6490 |
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https://hdl.handle.net/10495/34714 |
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eng |
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eng |
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Proc. Natl. Acad. Sci. U. S. A. |
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516 |
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2 |
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511 |
| dc.relation.citationvolume.spa.fl_str_mv |
109 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Proceedings of the National Academy of Sciences of the United States of America |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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National Academy of Sciences |
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Yalcindag, ErhanElguero, EricArnathau, CélineDurand, PatrickAkiana, JeanAnderson, Timothy JAubouy, AgnesBalloux, FrançoisBesnard, PatrickBogreau, HervéCarnevale, PierreD'Alessandro, UmbertoFontenille, DidierGamboa, DioniciaJombart, ThibautLe Mire, JacquesLeroy, EricMaestre Buitrago, Amanda ElenaMayxay, MayfongMénard, DidierMusset, LiseNewton, Paul N.Nkoghé, DieudonnéNoya, OscarOllomo, BenjaminRogier, ChristopheVeron, VincentWide, AlbinaZakeri, SedighehCarme, BernardLegrand, EricChevillon, ChristineAyala Pereda, Francisco JoséRenaud, FrançoisPrugnollea, FranckSalud y Comunidad2023-04-18T16:46:05Z2023-04-18T16:46:05Z2012Yalcindag E, Elguero E, Arnathau C, Durand P, Akiana J, Anderson TJ, Aubouy A, Balloux F, Besnard P, Bogreau H, Carnevale P, D'Alessandro U, Fontenille D, Gamboa D, Jombart T, Le Mire J, Leroy E, Maestre A, Mayxay M, Ménard D, Musset L, Newton PN, Nkoghé D, Noya O, Ollomo B, Rogier C, Veron V, Wide A, Zakeri S, Carme B, Legrand E, Chevillon C, Ayala FJ, Renaud F, Prugnolle F. Multiple independent introductions of Plasmodium falciparum in South America. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):511-6. doi: 10.1073/pnas.1119058109.0027-8424https://hdl.handle.net/10495/3471410.1073/pnas.1119058109091-6490ABSTRACT: The origin of Plasmodium falciparum in South America is controversial. Some studies suggest a recent introduction during the European colonizations and the transatlantic slave trade. Other evidence—archeological and genetic—suggests a much older origin. We collected and analyzed P. falciparum isolates from different regions of the world, encompassing the distribution range of the parasite, including populations from sub-Saharan Africa, the Middle East, Southeast Asia, and South America. Analyses of microsatellite and SNP polymorphisms show that the populations of P. falciparum in South America are subdivided in two main genetic clusters (northern and southern). Phylogenetic analyses, as well as Approximate Bayesian Computation methods suggest independent introductions of the two clusters from African sources. Our estimates of divergence time between the South American populations and their likely sources favor a likely introduction from Africa during the transatlantic slave trade.COL00474496application/pdfengNational Academy of SciencesWashington, Estados Unidossin facultad - programahttps://creativecommons.org/licenses/by-nc-nd/4.0/http://creativecommons.org/licenses/by-nc-nd/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Multiple Independent Introductions of Plasmodium Falciparum in South AmericaArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionHuman MigrationMigración HumanaGenetic VariationVariación GenéticaMalaria, FalciparumMalaria FalciparumPlasmodium FalciparumProc. Natl. Acad. Sci. U. S. 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