Cytotoxic activity of Amaryllidaceae plants against cancer cells: biotechnological, in vitro, and in silico approaches

ABSTRACT: Cancer is a major cause of death and an impediment to increasing life expectancy worldwide. With the aim of finding new molecules for chemotherapeutic treatment of epidemiological relevance, ten alkaloid fractions from Amaryllidaceae species were tested against six cancer cell lines (AGS,...

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Autores:

Trujillo Chacón, Lina Marcela
Bedoya Bedoya, Janeth Eliana
Gallego Gómez, Juan Carlos
Osorio Durango, Edison
Cortés Rendón, Natalie Charlotte
Leiva Cuenca, Yesin Hawer
Osorio López, Edison Humberto
Castro Restrepo, Dagoberto

Tipo de recurso:

Article of investigation

Fecha de publicación:

2023

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/42245

Acceso en línea:

https://hdl.handle.net/10495/42245

Palabra clave:

Alcaloides - química
Alkaloids - chemistry
Alcaloides de Amaryllidaceae - farmacología
Amaryllidaceae Alkaloids - pharmacology
Amaryllidaceae - química
Amaryllidaceae - chemistry
Antineoplásicos
Antineoplastic Agents
Simulación del Acoplamiento Molecular
Molecular Docking Simulation
Neoplasias
Neoplasms
Extractos Vegetales - farmacología
Plant Extracts - pharmacology
https://id.nlm.nih.gov/mesh/D000470
https://id.nlm.nih.gov/mesh/D047151
https://id.nlm.nih.gov/mesh/D000070378
https://id.nlm.nih.gov/mesh/D000970
https://id.nlm.nih.gov/mesh/D062105
https://id.nlm.nih.gov/mesh/D009369
https://id.nlm.nih.gov/mesh/D010936

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/