50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens

ABSTRACT: New species of Emmonsia-like fungi, with phylogenetic and clinical similarities to Blastomyces and Histoplasma, have emerged as causes of systemic human mycoses worldwide. They differ from classical Emmonsia species by producing a thermally-dependent, yeast-like phase rather than adiaspore...

Full description

Autores:
Muñoz Gómez, José Fernando
Schwartz, Ilan S.
Kenyon, Chris
Feng, Peiying
Govender, Nelesh P.
Dukik, Karolina
Sigler, Lynne
Jiang, Yanping
Stielow, J. Benjamin
Cuomo, Christina A.
Botha, Alfred
Stchigel, Alberto M.
de Hoog, G. Sybren
Tipo de recurso:
Article of investigation
Fecha de publicación:
2015
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/43976
Acceso en línea:
https://hdl.handle.net/10495/43976
Palabra clave:
Chrysosporium
Hongos
Fungi
Variación Genética
Genetic Variation
Micosis
Mycoses
Esporas Fúngicas
Spores, Fungal
Mortalidad
Mortality
Huésped Inmunocomprometido
Immunocompromised Host
https://id.nlm.nih.gov/mesh/D002912
https://id.nlm.nih.gov/mesh/D005658
https://id.nlm.nih.gov/mesh/D014644
https://id.nlm.nih.gov/mesh/D009181
https://id.nlm.nih.gov/mesh/D013172
https://id.nlm.nih.gov/mesh/D009026
https://id.nlm.nih.gov/mesh/D016867
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/
Description
Summary:ABSTRACT: New species of Emmonsia-like fungi, with phylogenetic and clinical similarities to Blastomyces and Histoplasma, have emerged as causes of systemic human mycoses worldwide. They differ from classical Emmonsia species by producing a thermally-dependent, yeast-like phase rather than adiaspores, and by causing disseminated infections, predominantly in immunocompromised patients and often with high case-fatality rates. Such differences will be important for clinicians to consider in diagnosis and patient management, and for microbiologists who may encounter these fungi with increasing frequency. (Tomado de la introducción del artículo)