Frequency of CYP3A5 Genetic Polymorphisms and Tacrolimus Pharmacokinetics in Pediatric Liver Transplantation

ABSTRACT: The evidence available in the pediatric population is limited for making clinical decisions regarding the optimization of tacrolimus (TAC) in pharmacotherapy. The objective of this study was to estimate the frequency of CYP3A5 genetic polymorphisms and their relationship with tacrolimus re...

Full description

Autores:

Buendía Rodríguez, Jefferson Antonio
Halac, Esteban
Bosaleh, Andrea
García de Dávila, María Teresa
Imvertasa, Óscar César
Bramuglia, Guillermo Federico

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/44827

Acceso en línea:

https://hdl.handle.net/10495/44827

Palabra clave:

Tacrolimus
Trasplante de Hígado
Liver Transplantation
Farmacocinética
Pharmacokinetics
Polimorfismo Genético
Polymorphism, Genetic
Citocromo P-450 CYP3A
Cytochrome P-450 CYP3A
https://id.nlm.nih.gov/mesh/D016559
https://id.nlm.nih.gov/mesh/D016031
https://id.nlm.nih.gov/mesh/D010599
https://id.nlm.nih.gov/mesh/D011110
https://id.nlm.nih.gov/mesh/D051544

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/