Production and characterization of chitosan-polyanion nanoparticles by polyelectrolyte complexation assisted by high-intensity sonication for the modified release of methotrexate

ABSTRACT: A promising strategy to improve the effectivity of anticancer treatment and decrease its side effects is to modulate drug release by using nanoparticulates (NPs) as carriers. In this study, methotrexate-loaded chitosan–polyanion nanoparticles were produced by polyelectrolyte complexation a...

Full description

Autores:

Ciro Monsalve, Yhors Alexander
Rojas Camargo, John Jairo
Carabali Balanta, Gustavo Adolfo
Alhajj Agualimpia, María José
Salamanca Mejía, Constain Hugo

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/38229

Acceso en línea:

https://hdl.handle.net/10495/38229

Palabra clave:

Quitosano
Chitosan
Polielectrolitos
Polyelectrolytes
Nanopartículas
Nanoparticles
Metotrexato
Methotrexate
https://id.nlm.nih.gov/mesh/D048271
https://id.nlm.nih.gov/mesh/D000071228
https://id.nlm.nih.gov/mesh/D053758
https://id.nlm.nih.gov/mesh/D008727

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/