Synthetic Peptide ∆M4-Induced Cell Death Associated with Cytoplasmic Membrane Disruption, Mitochondrial Dysfunction and Cell Cycle Arrest in Human Melanoma Cells
ABSTRACT: Melanoma is the most dangerous and lethal form of skin cancer, due to its ability to spread to different organs if it is not treated at an early stage. Conventional chemotherapeutics are failing as a result of drug resistance and weak tumor selectivity. Therefore, efforts to evaluate novel...
- Autores:
-
Patiño González, Edwin Bairon
Santa González, Gloria Angélica
Manrique Moreno, Marcela María
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/35178
- Acceso en línea:
- https://hdl.handle.net/10495/35178
- Palabra clave:
- Melanoma
Puntos de control del ciclo celular
Cell Cycle Checkpoints
Péptidos Antimicrobianos
Antimicrobial Peptides
Neoplasias Cutáneas
Skin Neoplasms
Muerte Celular
Cell Death
Membrana Celular
Cell Membrane
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/