In silico MLST for Aspergillus species identification and CYP51 gene characterization

ABSTRACT: Aspergillus spp. is an environmental fungi that can causes from localized infectious and allergic forms, to severe invasive disseases1; these clinical entities are a major health problem, with a rapidly evolving epidemiology and new groups of patients at risk2. A. fumigatus is the major et...

Full description

Autores:
Zuleta González, María Camila
Torres Morales, Susana
López García, Ángela María
Gómez Guzmán, Oscar Mauricio
Misas Rivas, Elizabeth
Rúa Giraldo, Alvaro León
Hernández Ruiz, Orville
Tipo de recurso:
http://purl.org/coar/resource_type/c_6670
Fecha de publicación:
2022
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/29940
Acceso en línea:
https://hdl.handle.net/10495/29940
Palabra clave:
Aspergillus
Familia 51 del Citocromo P450
Cytochrome P450 Family 51 F
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-sa/4.0/
id UDEA2_390539c244f0bfe3fee2f6558c6948b9
oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/29940
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv In silico MLST for Aspergillus species identification and CYP51 gene characterization
title In silico MLST for Aspergillus species identification and CYP51 gene characterization
spellingShingle In silico MLST for Aspergillus species identification and CYP51 gene characterization
Aspergillus
Familia 51 del Citocromo P450
Cytochrome P450 Family 51 F
title_short In silico MLST for Aspergillus species identification and CYP51 gene characterization
title_full In silico MLST for Aspergillus species identification and CYP51 gene characterization
title_fullStr In silico MLST for Aspergillus species identification and CYP51 gene characterization
title_full_unstemmed In silico MLST for Aspergillus species identification and CYP51 gene characterization
title_sort In silico MLST for Aspergillus species identification and CYP51 gene characterization
dc.creator.fl_str_mv Zuleta González, María Camila
Torres Morales, Susana
López García, Ángela María
Gómez Guzmán, Oscar Mauricio
Misas Rivas, Elizabeth
Rúa Giraldo, Alvaro León
Hernández Ruiz, Orville
dc.contributor.author.none.fl_str_mv Zuleta González, María Camila
Torres Morales, Susana
López García, Ángela María
Gómez Guzmán, Oscar Mauricio
Misas Rivas, Elizabeth
Rúa Giraldo, Alvaro León
Hernández Ruiz, Orville
dc.contributor.researchgroup.spa.fl_str_mv Biología Celular y Molecular CIB U. de A. U. del Rosario
Grupo de Investigación en Microbiología Básica y Aplicada-Microba
dc.subject.decs.none.fl_str_mv Aspergillus
Familia 51 del Citocromo P450
Cytochrome P450 Family 51 F
topic Aspergillus
Familia 51 del Citocromo P450
Cytochrome P450 Family 51 F
description ABSTRACT: Aspergillus spp. is an environmental fungi that can causes from localized infectious and allergic forms, to severe invasive disseases1; these clinical entities are a major health problem, with a rapidly evolving epidemiology and new groups of patients at risk2. A. fumigatus is the major etiologic agent of aspergillosis, but a few other Aspergillus species such as A. niger, A. flavus and A. terreus can also cause infections3. While most of these pathogens are phenotypically distinguished to section level, there is not enough resolution power to identify the species between the same section as they share near identical morphological characteristics4. For that reason, genomic identification of Aspergillus species is an alternative with better resolution power; and it provides additional information about biological, virulence and drugs resistance characteristics. The objective was to identify Aspergillus species through MLST and characterize the CYP51 gene
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2022-08-03T18:12:32Z
dc.date.available.none.fl_str_mv 2022-08-03T18:12:32Z
dc.date.issued.none.fl_str_mv 2022
dc.type.spa.fl_str_mv Póster de conferencia
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_c94f
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6670
dc.type.redcol.spa.fl_str_mv https://purl.org/redcol/resource_type/EC
dc.type.coarversion.spa.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/conferenceObject
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
format http://purl.org/coar/resource_type/c_6670
status_str publishedVersion
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10495/29940
url https://hdl.handle.net/10495/29940
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.conferencedate.spa.fl_str_mv 2022-06-09/2022-06-13
dc.relation.conferenceplace.spa.fl_str_mv Washington, Estados Unidos
dc.relation.ispartofjournal.spa.fl_str_mv ASM Microbe 2022
dc.rights.uri.spa.fl_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-sa/2.5/co/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
http://creativecommons.org/licenses/by-nc-sa/2.5/co/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.extent.spa.fl_str_mv 1
dc.format.mimetype.spa.fl_str_mv application/pdf
institution Universidad de Antioquia
bitstream.url.fl_str_mv https://bibliotecadigital.udea.edu.co/bitstreams/bf6ea2d9-d304-490f-85ac-f7ea2c3013a8/download
https://bibliotecadigital.udea.edu.co/bitstreams/c591b502-797c-48b3-8942-f0f8d2bc0b62/download
https://bibliotecadigital.udea.edu.co/bitstreams/aa31af7b-f294-4261-b1d7-dbffbf8bf4a8/download
https://bibliotecadigital.udea.edu.co/bitstreams/9b52be04-e321-4360-a031-958948802f57/download
https://bibliotecadigital.udea.edu.co/bitstreams/bd860b25-2a04-4e89-8cda-1ed13b169255/download
bitstream.checksum.fl_str_mv e2060682c9c70d4d30c83c51448f4eed
8a4605be74aa9ea9d79846c1fba20a33
594b8bc06a0eb1c114f4b6abedd8fd16
ba8f69418a81e2f26741f2a4a026e283
15af04c5f1af756abbdf0c929fd8ed10
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Institucional de la Universidad de Antioquia
repository.mail.fl_str_mv aplicacionbibliotecadigitalbiblioteca@udea.edu.co
_version_ 1851052580842504192
spelling Zuleta González, María CamilaTorres Morales, SusanaLópez García, Ángela MaríaGómez Guzmán, Oscar MauricioMisas Rivas, ElizabethRúa Giraldo, Alvaro LeónHernández Ruiz, OrvilleBiología Celular y Molecular CIB U. de A. U. del RosarioGrupo de Investigación en Microbiología Básica y Aplicada-Microba2022-08-03T18:12:32Z2022-08-03T18:12:32Z2022https://hdl.handle.net/10495/29940ABSTRACT: Aspergillus spp. is an environmental fungi that can causes from localized infectious and allergic forms, to severe invasive disseases1; these clinical entities are a major health problem, with a rapidly evolving epidemiology and new groups of patients at risk2. A. fumigatus is the major etiologic agent of aspergillosis, but a few other Aspergillus species such as A. niger, A. flavus and A. terreus can also cause infections3. While most of these pathogens are phenotypically distinguished to section level, there is not enough resolution power to identify the species between the same section as they share near identical morphological characteristics4. For that reason, genomic identification of Aspergillus species is an alternative with better resolution power; and it provides additional information about biological, virulence and drugs resistance characteristics. The objective was to identify Aspergillus species through MLST and characterize the CYP51 geneCOL0000962COL01261311application/pdfenghttps://creativecommons.org/licenses/by-nc-sa/4.0/http://creativecommons.org/licenses/by-nc-sa/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2In silico MLST for Aspergillus species identification and CYP51 gene characterizationPóster de conferenciahttp://purl.org/coar/resource_type/c_6670http://purl.org/coar/resource_type/c_c94fhttps://purl.org/redcol/resource_type/EChttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/publishedVersionAspergillusFamilia 51 del Citocromo P450Cytochrome P450 Family 51 F2022-06-09/2022-06-13Washington, Estados UnidosASM Microbe 2022PublicationCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81051https://bibliotecadigital.udea.edu.co/bitstreams/bf6ea2d9-d304-490f-85ac-f7ea2c3013a8/downloade2060682c9c70d4d30c83c51448f4eedMD52falseAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/c591b502-797c-48b3-8942-f0f8d2bc0b62/download8a4605be74aa9ea9d79846c1fba20a33MD53falseAnonymousREADORIGINALZuletaMaria_2022_AspergillusSpeciesIdentification.pdfZuletaMaria_2022_AspergillusSpeciesIdentification.pdfPósterapplication/pdf1509290https://bibliotecadigital.udea.edu.co/bitstreams/aa31af7b-f294-4261-b1d7-dbffbf8bf4a8/download594b8bc06a0eb1c114f4b6abedd8fd16MD51trueAnonymousREADTEXTZuletaMaria_2022_AspergillusSpeciesIdentification.pdf.txtZuletaMaria_2022_AspergillusSpeciesIdentification.pdf.txtExtracted texttext/plain14494https://bibliotecadigital.udea.edu.co/bitstreams/9b52be04-e321-4360-a031-958948802f57/downloadba8f69418a81e2f26741f2a4a026e283MD54falseAnonymousREADTHUMBNAILZuletaMaria_2022_AspergillusSpeciesIdentification.pdf.jpgZuletaMaria_2022_AspergillusSpeciesIdentification.pdf.jpgGenerated Thumbnailimage/jpeg11273https://bibliotecadigital.udea.edu.co/bitstreams/bd860b25-2a04-4e89-8cda-1ed13b169255/download15af04c5f1af756abbdf0c929fd8ed10MD55falseAnonymousREAD10495/29940oai:bibliotecadigital.udea.edu.co:10495/299402025-03-27 00:36:25.064https://creativecommons.org/licenses/by-nc-sa/4.0/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.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