Monoamine and Iron-related Toxicity : From Serotonin-binding Proteins to Lipid Peroxidation and Apoptosis in PC12 Cells
ABSTRACT: 1. Monoamines do not form coordination bonds with a preformed iron–serotonin-binding protein (SBP) complex, as initially believed. Instead, metals oxidize the monoamines either directly (manganese, copper) or by oxygen free radical formation (iron), the oxidation products bind covalently t...
- Autores:
-
Vélez Pardo, Carlos Alberto
Jiménez del Río, Marlene
Ebinger, Guy
Vauquelin, Georges
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 1998
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/34000
- Acceso en línea:
- https://hdl.handle.net/10495/34000
https://www.sciencedirect.com/science/article/pii/S0306362397004400?via%3Dihub
- Palabra clave:
- Lipid Peroxidation
Peroxidación de Lípido
Apoptosis
Apoptosis
Monoamine Oxidase
Monoaminooxidasa
Iron
Hierro
PC12 Cells
Células PC12
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/