Antiphospholipid Antibodies From Women With Pregnancy Morbidity and Vascular Thrombosis Induce Endothelial Mitochondrial Dysfunction, mTOR Activation, and Autophagy

ABSTRACT: Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombosis and pregnancy morbidity (PM) obstetric events together with persistent high titers of circulating antiphospholipid antibodies (aPL). Several mechanisms that explain the development of thrombosis and PM in...

Full description

Autores:

Cadavid Jaramillo, Angela Patricia
Álvarez Gómez, Angela María
Rua Molina, Diana Carolina
Rodríguez Colorado, Carlos Mario
Velásquez Berrío, Manuela
Abrahams, Vikki M.
Viana, Marta

Tipo de recurso:

Article of investigation

Fecha de publicación:

2021

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43624

Acceso en línea:

https://hdl.handle.net/10495/43624
http://www.frontiersin.org/physiology/archive

Palabra clave:

Anticuerpos Antifosfolípidos
Antibodies, Antiphospholipid
Células Endoteliales
Endothelial Cells
Autofagia
Autophagy
Síndrome Antifosfolípido
Antiphospholipid syndrome
Enfermedades Autoinmunes
Autoimmune Diseases
Complicaciones del Embarazo
Pregnancy Complications
https://id.nlm.nih.gov/mesh/D017152
https://id.nlm.nih.gov/mesh/D042783
https://id.nlm.nih.gov/mesh/D001343
https://id.nlm.nih.gov/mesh/D016736
https://id.nlm.nih.gov/mesh/D001327
https://id.nlm.nih.gov/mesh/D011248

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/