Risk factors for oronasal fistula in primary palatoplasty : a case-control study from a reference center in Medellín, Colombia

ABSTRACT: Background: Oronasal fistula is one of the most critical complications in primary palatoplasty, with a reported incidence between 5% and 46% with multiple associated risk factors described previously. Additionally, in more than half of the patients, it implies additional surgeries, increasing risks for the patient and health care costs. In this case-control study, we aim to determine the specific risk factors for oronasal fistula after primary palatoplasty in the study population. Methods: A retrospective review was undertaken to identify all patients undergoing primary palatoplasty between 2017 and 2019. Patients who developed oronasal fistula were included (cases) and compared with patients from the same cohort without fistula (controls). Demographic, clinical, and perioperative variables and their association with postoperative fistula presentation were explored through crude and adjusted analysis. Results: 139 patients with a median age of 6 years (5-6) who underwent primary palatoplasty were found. Forty-five presented oronasal fistula, corresponding to 32% of the population, and 64% required subsequent repair of an oronasal fistula. In the crude analysis, the surgeon's experience (OR 0.44) was associated significantly with the outcome. Adjusted analysis showed an association between surgical site infection and syndromic presentation. Conclusions: The experience of the surgeon is a protective factor for the oronasal fistula presentation; in addition, the presentation of infection of the operative site, the syndromic presentation, and the clinical follow-up at one year were also relevant; the latter, possibly due to the social context of our patients.

• Autores: Correa Acebedo, Esteban; Vásquez Sañudo, Vanesa; Vélez Toro, Juan Sebastián
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2023
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/39927
• Acceso en línea: https://hdl.handle.net/10495/39927
• Palabra clave: Cleft palate; Fisura del paladar; Palate - Surgery; Hueso paladar - Cirugía; Risk factors; Factores de riesgo; Postoperative complications; Complicaciones posoperatorias; Oronasal fistula; https://id.nlm.nih.gov/mesh/D002972; https://id.nlm.nih.gov/mesh/D010159; https://id.nlm.nih.gov/mesh/D012307; https://id.nlm.nih.gov/mesh/D011183
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc-sa/2.5/co/