Demonstration of Therapeutic Equivalence of Fluconazole Generic Products in the Neutropenic Mouse Model of Disseminated Candidiasi

ABSTRACT: Some generics of antibacterials fail therapeutic equivalence despite being pharmaceutical equivalents of their innovators, but data are scarce with antifungals. We used the neutropenic mice model of disseminated candidiasis to challenge the therapeutic equivalence of three generic products...

Full description

Autores:

González Pérez, Javier Mauricio
Rodríguez Jaramillo, Carlos Andrés
Zuluaga Salazar, Andrés Felipe
Agudelo Pérez, María
Vesga Meneses, Omar

Tipo de recurso:

Article of investigation

Fecha de publicación:

2015

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39094

Acceso en línea:

https://hdl.handle.net/10495/39094

Palabra clave:

Antifúngicos
Antifungal Agents
Área Bajo la Curva
Area Under Curve
Candida albicans
Candidiasis
Cromatografía Líquida de Alta Presión
Chromatography, High Pressure Liquid
Modelos Animales de Enfermedad
Disease Models, Animal
Medicamentos Genéricos
Drugs, Generic
Fluconazol
Fluconazole
Equivalencia Terapéutica
Therapeutic Equivalency
https://id.nlm.nih.gov/mesh/D000935
https://id.nlm.nih.gov/mesh/D019540
https://id.nlm.nih.gov/mesh/D002176
https://id.nlm.nih.gov/mesh/D002177
https://id.nlm.nih.gov/mesh/D002851
https://id.nlm.nih.gov/mesh/D004195
https://id.nlm.nih.gov/mesh/D016568
https://id.nlm.nih.gov/mesh/D015725
https://id.nlm.nih.gov/mesh/D013810

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/