Outbreak report of SARS-CoV-2 infection by airborne transmission: Epidemiologic and molecular evidence

ABSTRACT: Introduction: It has been shown that the transmission of SARS-CoV-2 occurs mainly by air, and the risk of infection is greater in closed spaces. Objective: To describe the epidemiology, virology and molecular characterization of a COVID-19 outbreak at a closed vaccination point during the third wave of SARS-CoV-2 in Colombia. Materials and methods: Diagnostic tests, interviews, sampling, cell cultures and viral sequencing were carried out, the latter being molecular characterization and lineage identification. Results: Seven workers were positive for SARS-CoV-2; among these, 3 samples were analyzed, plus an additional sample belonging to the mother of the presumed index case; all samples were identified with lineage B.1.625, with a maximum of 2 nucleotides difference between them. Conclusions: Variant B.1.625 was identified as the cause of the COVID-19 outbreak, and a co-worker was also identified as the index case. Unexpectedly, attending a vaccination day became a risk factor for acquiring the infection.

• Autores: Rugeles Lopez, María Teresa; Navas Navas, María Cristina; Cerón Chavez, Juan David; AguilarJiménez, Wbeimar; Díaz Castrillón, Francisco Javier
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2023
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/35329
• Acceso en línea: https://hdl.handle.net/10495/35329
• Palabra clave: SARS-CoV-2; Síndrome Respiratorio Agudo Grave; Severe Acute Respiratory Syndrome; Brotes de Enfermedades; Disease Outbreaks; Enfermedades Transmisibles; Communicable Diseases; Vacunación; Vaccination; SARS-CoV-2 - Colombia
• Rights: openAccess
• License: https://creativecommons.org/licenses/by/4.0/