The first chemically-synthesised, highly immunogenic anti-SARS-CoV 2 peptides in DNA genotyped aotus monkeys for human use

ABSTRACT: Thirty-five peptides selected from functionally-relevant SARS-CoV-2 spike (S), membrane (M), and envelope (E) proteins were suitably modified for immunising MHC class II (MHCII) DNA-genotyped Aotus monkeys and matched with HLA-DRb1* molecules for use in humans. This was aimed at producing...

Full description

Autores:

Rugeles López, María Teresa
Aguilar Jiménez, Wbeimar
Flórez Álvarez, Lizdany
Pabón, Laura
Patarroyo, Manuel Elkin
Patarroyo, Manuel Alonso
Alba, Martha P.
Bermúdez, Abriana
Rout, Ashok k.
Griesinger, Cristina
Suarez Martínez, Carlos Fernando
Aza Conde, Jorge
Reyes, Cesar
Avendaño, Catalina
Samacá, Jhoan
Camargo, Anny
Silva, Yolanda
Forero, Martha
González, Edgardo

Tipo de recurso:

Article of investigation

Fecha de publicación:

2021

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/36775

Acceso en línea:

https://hdl.handle.net/10495/36775

Palabra clave:

SARS-CoV-2
Péptidos
Peptides
Anticuerpos ampliamente neutralizantes
Broadly Neutralizing Antibodies
Anticuerpos Virales
Antibodies, Viral
Vacunas contra la COVID-19
COVID-19 Vaccines
Cadenas HLA-DRB1
HLA-DRB1 Chains
Glicoproteína de la Espiga del Coronavirus
Spike Glycoprotein, Coronavirus
Virosis
Virus Diseases

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/