Systemic lupus erythematosus in males. A study of 107 Latin American patients

ABSTRACT: Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.

• Autores: Molina Restrepo, José Fernando; Anaya Cabrera, Juan Manuel; Drenkard, Cristina; Molina Lopéz, Javier; Cardiel Ríos, Mario Humberto; Uribe Uribe, Oscar; Gómez Domínguez, Luis; Felipe Díaz, Oscar Jair; Ramírez, Luis A; Alarcon Segovia, Donato
• Tipo de recurso: Article of investigation
• Fecha de publicación: 1996
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/38746
• Acceso en línea: https://hdl.handle.net/10495/38746
• Palabra clave: Causas de Muerte; Cause of Death; Lupus Eritematoso Sistémico; Lupus Erythematosus, Systemic; Índice de Severidad de la Enfermedad; Severity of Illness Index; Caracteres Sexuales; Sex Characteristics; Estudios Transversales; Cross-Sectional Studies; https://id.nlm.nih.gov/mesh/D002423; https://id.nlm.nih.gov/mesh/D008180; https://id.nlm.nih.gov/mesh/D012720; https://id.nlm.nih.gov/mesh/D012727; https://id.nlm.nih.gov/mesh/D003430
• Rights: openAccess
• License: https://creativecommons.org/licenses/by-nc-nd/4.0/