Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium

ABSTRACT: Hispanic/Latinos have been underrepresented in genome-wide association studies (GWAS) for anthropometric traits despite their notable anthropometric variability, ancestry proportions, and high burden of growth stunting and overweight/obesity. To address this knowledge gap, we analyzed dens...

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Autores:

Bedoya Berrío, Gabriel de Jesús
Ruíz Linares, Andrés
Graff, Mariaelisa
Buchanan, Victoria L.
Justice, Anne E.
Highland, Heather M.
Guo, Xiuqing
Zhu, Wanying
Chen, Hung-Hsin
Young, Kristin L.
Adhikari, Kaustubh
Cole, Shelley A.
Comuzzie, Anthony G.
Voruganti, V Saroja
Rohde, Rebecca
Wang, Yujie
Sofer, Tamar
Ziv, Elad
Grant, Struan F. A.
Fernández Rhodes, Lindsay
Rotter, Jerome I.
Palmer, Nicholette D.
Haiman, Christopher A.
Parra, Esteban J.
Cruz, Miguel
Loos, Ruth J. F.
North, Kari E.
Below, Jennifer E.
Bradfield, Jonathan
Pereira, Alexandre C.
Glover, LáShauntá
Kim, Daeeun
Lilly, Adam G.
Shrestha, Poojan
Thomas, Alvin G.
Zhang, Xinruo
Chen, Minhui
Chiang, Charleston W. K.
Pulit, Sara
Horimoto, Andrea
Krieger, Jose E
Guindo Martínez, Marta
Preuss, Michael
Schumann, Claudia
Smit, Roelof A. J.
Torres Mejía, Gabriela
Acuña Alonzo, Victor
Bortolini, Maria Cátira
Canizales Quinteros, Samuel
Gallo, Carla
González José, Rolando
Poletti, Giovanni
Rothhammer, Francisco
Hakonarson, Hakon
Igo, Robert
Adler, Sharon G.
Iyengar, Sudha K
Nicholas, Susanne B.
Gogarten, Stephanie M.
Isasi, Carmen R.
Papnicolaou, George
Stilp, Adrienne M.
Qi, Qibin
Kho, Minjung
Smith, Jennifer A.
Langefeld, Carl D.
Wagenknecht, Lynne
Mckean Cowdin, Roberta
Gao Xiaoyi, Raymond
Nousome, Darryl
Conti, David V.
Feng, Ye
Allison, Matthew A
Arzumanyan, Zorayr
Chen, Yii-Der Ida
Genter, Pauline M.
Goodarzi, Mark O.
Hai, Yang
Hsueh, Willa
Ipp, Eli
Kandeel, Fouad R.
Lam, Kelvin
Li, Xiaohui
Nadler, Jerry L.
Raffel, Leslie J.
Roll, Kathryn
Sandow, Kevin
Tan, Jingyi
Taylor, Kent D.
Xiang, Anny H.
Yao, Jie
Audirac-Chalifour, Astride
Peralta Romero, José de Jesús
Hartwig, Fernando
Horta, Bernando
Blangero, John
Curran, Joanne E.
Duggirala, Ravindranath
Lehman, Donna E.
Puppala, Sobha
Fejerman, Laura
John, Esther M.
Aguilar Salinas, Carlos
Burtt, Noël P.
Florez, Jose C.
García Ortíz, Humberto
González Villalpando, Clicerio
Mercader, Josep
Orozco, Lorena
Tusié Luna, Teresa
Blanco, Estela
Gahagan, Sheila
Cox, Nancy J.
Hanis, Craig
Butte, Nancy F.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/41086

Acceso en línea:

https://hdl.handle.net/10495/41086
https://www.sciencedirect.com/journal/human-genetics-and-genomics-advances

Palabra clave:

Hispánicos o Latinos
Hispanic or Latino
Variación Genética
Genetic Variation
Mapeo Cromosómico
Chromosome Mapping
Obesidad
Obesity
Antropometría
Anthropometry
https://id.nlm.nih.gov/mesh/D006630
https://id.nlm.nih.gov/mesh/D014644
https://id.nlm.nih.gov/mesh/D002874
https://id.nlm.nih.gov/mesh/D009765

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/