Rhodnius prolixus Life History Outcomes Differ when Infected with Different Trypanosoma cruzi I Strains

The effect of a parasite on the life history of its vector is important for understanding and predicting disease transmission. Chagas disease agent Trypanosoma cruzi is a generalist parasite that is diverse across scales from its genetic diversity to the 100s of mammal and vector species it infects. Its vertebrate hosts show quite variable responses to infec tion, however, to date there are no studies looking at how T. cruzi variability might result in variable outcomes in its invertebrate host. Therefore, we investigated the effect of different T. cruzi IstrainsonRhodnius prolixus survival and development. We found significant variation between insects infected with different strains, with some strains having no effect, as compared with uninfected insects, and others with significantly lower survival and development. We also found that different variables had varying importance between strains, with the effect of time postinfection and the blood:weight ratio of the infective meal significantly affecting the survival of insects infected with some strains, but not others. Our results suggest that T. cruzi can be pathogenic not only to its vertebrate hosts but also to its invertebrate hosts.

• Autores: Peterson, Jennifer K.; Graham, Andrea L.; Dobson, Andrew P.; Triana Chávez, Omar
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2015
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/48246
• Acceso en línea: https://hdl.handle.net/10495/48246
• Palabra clave: 610 - Medicina y salud::616 - Enfermedades; Enfermedad de Chagas; Chagas Disease; Insectos Vectores; Insect Vectors; Análisis de Supervivencia; Survival Analysis; Trypanosoma cruzi; Medicina Tropical; Tropical Medicine; Estadios del Ciclo de Vida; Life Cycle Stages; Ninfa; Nymph; Rhodnius prolixus; http://aims.fao.org/aos/agrovoc/c_30704; http://id.loc.gov/authorities/subjects/sh90003967; https://id.nlm.nih.gov/mesh/D014355; https://id.nlm.nih.gov/mesh/D007303; https://id.nlm.nih.gov/mesh/D016019; https://id.nlm.nih.gov/mesh/D014349; http://id.nlm.nih.gov/mesh/D014330; https://id.nlm.nih.gov/mesh/D008018; https://id.nlm.nih.gov/mesh/D009758; ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades
• Rights: openAccess
• License: http://creativecommons.org/licenses/by/4.0/