Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review
ABSTRACT: Introduction: Aggressive variants of papillary thyroid cancer (PTC) have been described with increasing frequency. These variants include diffuse sclerosing variant, tall cell variant, columnar cell variant, solid variant, and hobnail variant. Methods: We have performed a review of the mor...
- Autores:
-
Sanabria Quiroga, Álvaro Enrique
Coca Pelaz, Andrés
Shah, Jatin P.
Hernández Prera, Juan C.
Ghossein, Ronald A.
Rodrigo, Juan P.
Hartl, Dana M.
Olsen, Kerry D.
Shaha, Ashok R.
Zafereo, Mark
Suarez, Carlos
Nixon, Iain J.
Randolph, Gregory W.
Mäkitie, Antti A.
Kowalski, Luiz P.
Vander Poorten, Vincent
Guntinas Lichius, Orlando
Simo, Ricard
Zbären, Peter
Angelos, Peter
Khafif, Avi
Rinaldo, Alessandra
Ferlito, Alfio
- Tipo de recurso:
- Review article
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/43072
- Acceso en línea:
- https://hdl.handle.net/10495/43072
- Palabra clave:
- Carcinoma, Papillary
Carcinoma Papilar
Genetic Variation
Variación Genética
Thyroid Cancer, Papillary
Cáncer Papilar Tiroideo
Thyroid Neoplasms
Neoplasias de la Tiroides
https://id.nlm.nih.gov/mesh/D002291
https://id.nlm.nih.gov/mesh/D014644
https://id.nlm.nih.gov/mesh/D000077273
https://id.nlm.nih.gov/mesh/D013964
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc/2.5/co/
| id |
UDEA2_063e9028a6ad65ce40c97fe365401785 |
|---|---|
| oai_identifier_str |
oai:bibliotecadigital.udea.edu.co:10495/43072 |
| network_acronym_str |
UDEA2 |
| network_name_str |
Repositorio UdeA |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review |
| title |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review |
| spellingShingle |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review Carcinoma, Papillary Carcinoma Papilar Genetic Variation Variación Genética Thyroid Cancer, Papillary Cáncer Papilar Tiroideo Thyroid Neoplasms Neoplasias de la Tiroides https://id.nlm.nih.gov/mesh/D002291 https://id.nlm.nih.gov/mesh/D014644 https://id.nlm.nih.gov/mesh/D000077273 https://id.nlm.nih.gov/mesh/D013964 |
| title_short |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review |
| title_full |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review |
| title_fullStr |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review |
| title_full_unstemmed |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review |
| title_sort |
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review |
| dc.creator.fl_str_mv |
Sanabria Quiroga, Álvaro Enrique Coca Pelaz, Andrés Shah, Jatin P. Hernández Prera, Juan C. Ghossein, Ronald A. Rodrigo, Juan P. Hartl, Dana M. Olsen, Kerry D. Shaha, Ashok R. Zafereo, Mark Suarez, Carlos Nixon, Iain J. Randolph, Gregory W. Mäkitie, Antti A. Kowalski, Luiz P. Vander Poorten, Vincent Guntinas Lichius, Orlando Simo, Ricard Zbären, Peter Angelos, Peter Khafif, Avi Rinaldo, Alessandra Ferlito, Alfio |
| dc.contributor.author.none.fl_str_mv |
Sanabria Quiroga, Álvaro Enrique Coca Pelaz, Andrés Shah, Jatin P. Hernández Prera, Juan C. Ghossein, Ronald A. Rodrigo, Juan P. Hartl, Dana M. Olsen, Kerry D. Shaha, Ashok R. Zafereo, Mark Suarez, Carlos Nixon, Iain J. Randolph, Gregory W. Mäkitie, Antti A. Kowalski, Luiz P. Vander Poorten, Vincent Guntinas Lichius, Orlando Simo, Ricard Zbären, Peter Angelos, Peter Khafif, Avi Rinaldo, Alessandra Ferlito, Alfio |
| dc.contributor.researchgroup.spa.fl_str_mv |
Trauma y Cirugía |
| dc.subject.decs.none.fl_str_mv |
Carcinoma, Papillary Carcinoma Papilar Genetic Variation Variación Genética Thyroid Cancer, Papillary Cáncer Papilar Tiroideo Thyroid Neoplasms Neoplasias de la Tiroides |
| topic |
Carcinoma, Papillary Carcinoma Papilar Genetic Variation Variación Genética Thyroid Cancer, Papillary Cáncer Papilar Tiroideo Thyroid Neoplasms Neoplasias de la Tiroides https://id.nlm.nih.gov/mesh/D002291 https://id.nlm.nih.gov/mesh/D014644 https://id.nlm.nih.gov/mesh/D000077273 https://id.nlm.nih.gov/mesh/D013964 |
| dc.subject.meshuri.none.fl_str_mv |
https://id.nlm.nih.gov/mesh/D002291 https://id.nlm.nih.gov/mesh/D014644 https://id.nlm.nih.gov/mesh/D000077273 https://id.nlm.nih.gov/mesh/D013964 |
| description |
ABSTRACT: Introduction: Aggressive variants of papillary thyroid cancer (PTC) have been described with increasing frequency. These variants include diffuse sclerosing variant, tall cell variant, columnar cell variant, solid variant, and hobnail variant. Methods: We have performed a review of the more aggressive variants of PTC with respect to main characteristics, histological and molecular features, and the consequences that the knowledge of these variants should have in the treatment of the patients. Results: At the present time, we do not know the prognostic value of these aggressive PTC variants. The extent of the surgical treatment and adjuvant therapy necessary should be decided on the basis of the extent of the tumor at presentation and the opinion of experienced clinicians. Conclusion: These aggressive variants should be known by clinicians, to avoid underdiagnosis, and treated according to the latest recommendations in the literature. Keywords: Aggressive variants papillary thyroid cancer; Columnar cell variant; Diffuse sclerosis variant; Hobnail variant; Solid variant; Tall cell variant. |
| publishDate |
2020 |
| dc.date.issued.none.fl_str_mv |
2020 |
| dc.date.accessioned.none.fl_str_mv |
2024-11-03T03:54:52Z |
| dc.date.available.none.fl_str_mv |
2024-11-03T03:54:52Z |
| dc.type.spa.fl_str_mv |
Artículo de revisión |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_dcae04bc |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ARTREV |
| dc.type.coarversion.spa.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
http://purl.org/coar/resource_type/c_dcae04bc |
| status_str |
publishedVersion |
| dc.identifier.citation.spa.fl_str_mv |
Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A. Papillary Thyroid Cancer-Aggressive Variants and Impact on Management: A Narrative Review. Adv Ther. 2020 Jul;37(7):3112-3128. doi: 10.1007/s12325-020-01391-1. |
| dc.identifier.issn.none.fl_str_mv |
0741-238X |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/43072 |
| dc.identifier.doi.none.fl_str_mv |
10.1007/s12325-020-01391-1 |
| dc.identifier.eissn.none.fl_str_mv |
1865-8652 |
| identifier_str_mv |
Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A. Papillary Thyroid Cancer-Aggressive Variants and Impact on Management: A Narrative Review. Adv Ther. 2020 Jul;37(7):3112-3128. doi: 10.1007/s12325-020-01391-1. 0741-238X 10.1007/s12325-020-01391-1 1865-8652 |
| url |
https://hdl.handle.net/10495/43072 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Adv. Ther. |
| dc.relation.citationendpage.spa.fl_str_mv |
3128 |
| dc.relation.citationissue.spa.fl_str_mv |
7 |
| dc.relation.citationstartpage.spa.fl_str_mv |
3112 |
| dc.relation.citationvolume.spa.fl_str_mv |
37 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Advances in Therapy |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ |
| dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ |
| dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.extent.spa.fl_str_mv |
17 páginas |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.spa.fl_str_mv |
Springer |
| dc.publisher.place.spa.fl_str_mv |
Nueva York, Estados Unidos |
| institution |
Universidad de Antioquia |
| bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstreams/b0f6d169-6c11-436a-94ae-7abf8c259ff3/download https://bibliotecadigital.udea.edu.co/bitstreams/c103fed7-c5dd-47af-b57f-86d5f2721793/download https://bibliotecadigital.udea.edu.co/bitstreams/b868a1c2-1ad5-4120-9901-1af2c880412d/download https://bibliotecadigital.udea.edu.co/bitstreams/2844a90b-1050-4b0c-a67a-8c49efecfd08/download |
| bitstream.checksum.fl_str_mv |
25d54fa0403f7e5fc0bddf7b5b01dc4e 8a4605be74aa9ea9d79846c1fba20a33 c7bf3b23f7400ac8bbc1290336e0516e 9abd046579131f9591bf45870ba61f8c |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional de la Universidad de Antioquia |
| repository.mail.fl_str_mv |
aplicacionbibliotecadigitalbiblioteca@udea.edu.co |
| _version_ |
1851052209626677248 |
| spelling |
Sanabria Quiroga, Álvaro EnriqueCoca Pelaz, AndrésShah, Jatin P.Hernández Prera, Juan C.Ghossein, Ronald A.Rodrigo, Juan P.Hartl, Dana M.Olsen, Kerry D.Shaha, Ashok R.Zafereo, MarkSuarez, CarlosNixon, Iain J.Randolph, Gregory W.Mäkitie, Antti A.Kowalski, Luiz P.Vander Poorten, VincentGuntinas Lichius, OrlandoSimo, RicardZbären, PeterAngelos, PeterKhafif, AviRinaldo, AlessandraFerlito, AlfioTrauma y Cirugía2024-11-03T03:54:52Z2024-11-03T03:54:52Z2020Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A. Papillary Thyroid Cancer-Aggressive Variants and Impact on Management: A Narrative Review. Adv Ther. 2020 Jul;37(7):3112-3128. doi: 10.1007/s12325-020-01391-1.0741-238Xhttps://hdl.handle.net/10495/4307210.1007/s12325-020-01391-11865-8652ABSTRACT: Introduction: Aggressive variants of papillary thyroid cancer (PTC) have been described with increasing frequency. These variants include diffuse sclerosing variant, tall cell variant, columnar cell variant, solid variant, and hobnail variant. Methods: We have performed a review of the more aggressive variants of PTC with respect to main characteristics, histological and molecular features, and the consequences that the knowledge of these variants should have in the treatment of the patients. Results: At the present time, we do not know the prognostic value of these aggressive PTC variants. The extent of the surgical treatment and adjuvant therapy necessary should be decided on the basis of the extent of the tumor at presentation and the opinion of experienced clinicians. Conclusion: These aggressive variants should be known by clinicians, to avoid underdiagnosis, and treated according to the latest recommendations in the literature. Keywords: Aggressive variants papillary thyroid cancer; Columnar cell variant; Diffuse sclerosis variant; Hobnail variant; Solid variant; Tall cell variant.COL001661217 páginasapplication/pdfengSpringerNueva York, Estados Unidoshttp://creativecommons.org/licenses/by-nc/2.5/co/https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative ReviewArtículo de revisiónhttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionCarcinoma, PapillaryCarcinoma PapilarGenetic VariationVariación GenéticaThyroid Cancer, PapillaryCáncer Papilar TiroideoThyroid NeoplasmsNeoplasias de la Tiroideshttps://id.nlm.nih.gov/mesh/D002291https://id.nlm.nih.gov/mesh/D014644https://id.nlm.nih.gov/mesh/D000077273https://id.nlm.nih.gov/mesh/D013964Adv. Ther.31287311237Advances in TherapyPublicationORIGINALSanabriaAlvaro_2020_Papillary_Thyroid_Cancer.pdfSanabriaAlvaro_2020_Papillary_Thyroid_Cancer.pdfArtículo de revisiónapplication/pdf1610715https://bibliotecadigital.udea.edu.co/bitstreams/b0f6d169-6c11-436a-94ae-7abf8c259ff3/download25d54fa0403f7e5fc0bddf7b5b01dc4eMD51trueAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/c103fed7-c5dd-47af-b57f-86d5f2721793/download8a4605be74aa9ea9d79846c1fba20a33MD52falseAnonymousREADTEXTSanabriaAlvaro_2020_Papillary_Thyroid_Cancer.pdf.txtSanabriaAlvaro_2020_Papillary_Thyroid_Cancer.pdf.txtExtracted texttext/plain65646https://bibliotecadigital.udea.edu.co/bitstreams/b868a1c2-1ad5-4120-9901-1af2c880412d/downloadc7bf3b23f7400ac8bbc1290336e0516eMD53falseAnonymousREADTHUMBNAILSanabriaAlvaro_2020_Papillary_Thyroid_Cancer.pdf.jpgSanabriaAlvaro_2020_Papillary_Thyroid_Cancer.pdf.jpgGenerated Thumbnailimage/jpeg13782https://bibliotecadigital.udea.edu.co/bitstreams/2844a90b-1050-4b0c-a67a-8c49efecfd08/download9abd046579131f9591bf45870ba61f8cMD54falseAnonymousREAD10495/43072oai:bibliotecadigital.udea.edu.co:10495/430722025-03-26 18:39:41.538http://creativecommons.org/licenses/by-nc/2.5/co/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.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 |