Folate deficiency modifies the risk of CIN3+ associated with DNA methylation levels: a nested case-control study from the ASCUS-COL trial

ABSTRACT: Purpose: To our knowledge, there are very few studies evaluating if the levels of folate modify the risk of cervical intraepithelial neoplasia grade 2 and higher (CIN2+ and CIN3+) associated with the levels of HPV genome methylation, two cofactors related to single carbon metabolism and in...

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Autores:
Agudelo Fernández, María Cecilia
Agudelo Gamboa, Samuel
Ramírez Pineda, Arianis Tatiana
Castañeda Vanegas, Kelly Melisa
Garcés Palacio, Isabel Cristina
Sánchez Vásquez, Gloria
Lorincz, Attila
Zea, Arnold H.
Piyathilake, Chandrika
Tipo de recurso:
Article of investigation
Fecha de publicación:
2024
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/45268
Acceso en línea:
https://hdl.handle.net/10495/45268
Palabra clave:
Atypical Squamous Cells of the Cervix
Células Escamosas Atípicas del Cuello del Útero
Case-Control Studies
Estudios de Casos y Controles
DNA Methylation
Metilación de ADN
Folic Acid
Ácido Fólico
Folic Acid Deficiency
Deficiencia de Ácido Fólico
Uterine Cervical Dysplasia
Displasia del Cuello del Útero
https://id.nlm.nih.gov/mesh/D065309
https://id.nlm.nih.gov/mesh/D016022
https://id.nlm.nih.gov/mesh/D019175
https://id.nlm.nih.gov/mesh/D005492
https://id.nlm.nih.gov/mesh/D005494
https://id.nlm.nih.gov/mesh/D002578
Rights
openAccess
License
https://creativecommons.org/licenses/by/4.0/