Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia
Este estudio tuvo como objetivo detectar la presencia de paramyxovirus en murciélagos del departamento de Córdoba, Colombia. Se analizaron muestras de 100 individuos pertenecientes a 11 especies de la familia Phyllostomidae, recolectadas en zonas urbanas, periurbanas y rurales. Se emplearon técnicas...
- Autores:
-
Gómez Navarro, Nayerlys
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2025
- Institución:
- Universidad de Córdoba
- Repositorio:
- Repositorio Institucional Unicórdoba
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unicordoba.edu.co:ucordoba/9544
- Acceso en línea:
- https://repositorio.unicordoba.edu.co/handle/ucordoba/9544
https://repositorio.unicordoba.edu.co/
- Palabra clave:
- RT-PCR
Zoonosis
Fauna silvestre
Vigilancia epidemiológica
Virus emergentes
RT-PCR
Zoonosis
Wildlife
Epidemiological Surveillance
Emerging viruses
- Rights
- openAccess
- License
- Copyright Universidad de Córdoba, 2025
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Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia |
| title |
Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia |
| spellingShingle |
Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia RT-PCR Zoonosis Fauna silvestre Vigilancia epidemiológica Virus emergentes RT-PCR Zoonosis Wildlife Epidemiological Surveillance Emerging viruses |
| title_short |
Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia |
| title_full |
Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia |
| title_fullStr |
Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia |
| title_full_unstemmed |
Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia |
| title_sort |
Detección de paramyxovirus en murciélagos del departamento de Córdoba, Colombia |
| dc.creator.fl_str_mv |
Gómez Navarro, Nayerlys |
| dc.contributor.advisor.none.fl_str_mv |
Echeverri de la Hoz, Daniel Mauricio Martínez Bravo, Caty Milena |
| dc.contributor.author.none.fl_str_mv |
Gómez Navarro, Nayerlys |
| dc.contributor.jury.none.fl_str_mv |
Pérez Cogollo, Luis Carlos Calderón Rangel, Alfonso |
| dc.subject.proposal.spa.fl_str_mv |
RT-PCR Zoonosis Fauna silvestre Vigilancia epidemiológica Virus emergentes |
| topic |
RT-PCR Zoonosis Fauna silvestre Vigilancia epidemiológica Virus emergentes RT-PCR Zoonosis Wildlife Epidemiological Surveillance Emerging viruses |
| dc.subject.keywords.eng.fl_str_mv |
RT-PCR Zoonosis Wildlife Epidemiological Surveillance Emerging viruses |
| description |
Este estudio tuvo como objetivo detectar la presencia de paramyxovirus en murciélagos del departamento de Córdoba, Colombia. Se analizaron muestras de 100 individuos pertenecientes a 11 especies de la familia Phyllostomidae, recolectadas en zonas urbanas, periurbanas y rurales. Se emplearon técnicas de biología molecular, utilizando RT-PCR semianidada dirigida al gen L del virus. La detección se confirmó por electroforesis en gel de agarosa. Se identificó un caso positivo en una hembra adulta de Phyllostomus discolor capturada en una zona rural del municipio de Chimá. Esta especie, de hábitos omnívoros y amplia capacidad de movimiento, podría haber facilitado su exposición al virus en distintos entornos. A pesar de la baja frecuencia, este hallazgo representa el primer reporte de paramyxovirus en murciélagos en Colombia. Los resultados destacan la necesidad de fortalecer la vigilancia epidemiológica de virus emergentes en fauna silvestre, ampliar el esfuerzo de muestreo y aplicar herramientas moleculares más sensibles. Además, se sugiere explorar el rol ecológico de los murciélagos en la diseminación viral, especialmente en ecosistemas compartidos con otras especies como las aves migratorias. |
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2025 |
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2025-09-03T16:31:21Z |
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2025-09-03T16:31:21Z |
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2025-09-02 |
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Trabajo de grado - Pregrado |
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info:eu-repo/semantics/bachelorThesis |
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http://purl.org/coar/resource_type/c_7a1f |
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Universidad de Córdoba |
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Repositorio Universidad de Córdoba |
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Almida, F. T., Veloz, N. S., & Puig, I. D. C. R. (2022). Estudio sobre convivencia entre población humana y murciélagos en la Universidad de Granma (Original). Redel. Revista Granmense de Desarrollo Local, 6(4), 383-405. Amarasinghe, G. K., Bào, Y., Basler, C. F., Bavari, S., Beer, M., Bejerman, N., Blasdell, K. R., Bochnowski, A., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Collins, P. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., … Kuhn, J. H. (2017). Taxonomy of the order Mononegavirales: update 2017. Archives of Virology, 162(8). https://doi.org/10.1007/s00705-017-3311-7 Anderson, S. C., & Ruxton, G. D. (2020). The evolution of flight in bats: a novel hypothesis. In Mammal Review (Vol. 50, Issue 4). https://doi.org/10.1111/mam.12211 Ayolabi, C. I., Olusola, B. A., Lawal, A. A., Chibuike, A. D., & Nzekwue, B. N. (2022). Detection of novel paramyxoviruses in Chaerephon bat species in Nigeria and phylogenetics of paramyxoviruses co-evolution with bats in Africa. Zoonoses and Public Health, 69(2). https://doi.org/10.1111/zph.12900 Beena, V., & Saikumar, G. (2019). Emerging horizon for bat borne viral zoonoses. In VirusDisease (Vol. 30, Issue 3). https://doi.org/10.1007/s13337-019-00548-z Calisher, C. H., Childs, J. E., Field, H. E., Holmes, K. V., & Schountz, T. (2006). Bats: Important reservoir hosts of emerging viruses. In Clinical Microbiology Reviews (Vol. 19, Issue 3). https://doi.org/10.1128/CMR.00017-06 Chan, J. F. W., To, K. K. W., Tse, H., Jin, D. Y., & Yuen, K. Y. (2013). Interspecies transmission and emergence of novel viruses: Lessons from bats and birds. In Trends in Microbiology (Vol. 21, Issue 10). https://doi.org/10.1016/j.tim.2013.05.005 Chang, A., & Dutch, R. E. (2012). Paramyxovirus fusion and entry: Multiple Paths to a common end. In Viruses (Vol. 4, Issue 4). https://doi.org/10.3390/v4040613 Cox, R., & Plemper, R. K. (2015). The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics. In Frontiers in Microbiology (Vol. 6, Issue MAY). https://doi.org/10.3389/fmicb.2015.00459 Darcissac, E., Donato, D., de Thoisy, B., Lacoste, V., & Lavergne, A. (2021). Paramyxovirus circulation in bat species from French Guiana. Infection, Genetics and Evolution, 90. https://doi.org/10.1016/j.meegid.2021.104769 de Souza, W. M., Fumagalli, M. J., Carrera, J. P., de Araujo, J., Cardoso, J. F., de Carvalho, C., Durigon, E. L., Queiroz, L. H., Faria, N. R., Murcia, P. R., & Figueiredo, L. T. M. (2021). Paramyxoviruses from neotropical bats suggest a novel genus and nephrotropism. Infection, Genetics and Evolution, 95, 105041. https://doi.org/10.1016/J.MEEGID.2021.105041 Dutheil, F., Clinchamps, M., & Bouillon-Minois, J. B. (2021). Bats, pathogens, and species richness. Pathogens, 10(2). https://doi.org/10.3390/pathogens10020098 Esquivel, D. A., Aya-Cuero, C. A., Peña, S., Velásquez-Guarín, D., & Ramírez-Chaves, H. E. (2020). Bats (Chiroptera) in the department of Tolima, Colombia: diversity in a humid tropical forest and updated species list for Department. Boletin Cientifico Del Centro de Museos, 24(2). https://doi.org/10.17151/bccm.2020.24.2.6 Glinski, Z., & Ciolek, J. (2020). Bats as reservoir and vector of viruses pathogenic for humans and animals. Zycie Weterynaryjne, 95(1). Gorbunova, V., Seluanov, A., & Kennedy, B. K. (2020). The World Goes Bats: Living Longer and Tolerating Viruses. In Cell Metabolism (Vol. 32, Issue 1). https://doi.org/10.1016/j.cmet.2020.06.013 Gupta, P., Singh, M. P., Goyal, K., Tripti, P., Ansari, M. I., Obli Rajendran, V., Dhama, K., & Malik, Y. S. (2021). Bats and viruses: a death-defying friendship. In VirusDisease (Vol. 32, Issue 3). https://doi.org/10.1007/s13337-021-00716-0 Hernández, E. Y. M., & López, Z. I. V. (2019). La otra cara de los murciélagos. Revista Mesoamericana de Biodiversidad y Cambio Climático, 3(6), 46-49. Han, H. J., Wen, H. ling, Zhou, C. M., Chen, F. F., Luo, L. M., Liu, J. wei, & Yu, X. J. (2015). Bats as reservoirs of severe emerging infectious diseases. In Virus Research (Vol. 205). https://doi.org/10.1016/j.virusres.2015.05.006 Karen, S. H., Gabriela, S. M., Bruno, M. G., Maria, S., Lenin, M. H., & Daniel, G. B. (2016). Prevalence of paramyxoviruses in bats in six areas of madre de dios and puno, Peru with two levels of anthropogenic disturbance. Revista de Investigaciones Veterinarias Del Peru, 27(2). https://doi.org/10.15381/rivep.v27i2.11640 Kłys, G., Ziembik, Z., & Makuchowska-Fryc, J. (2024). Bat Hibernation: In Groups or Individually? Applied Sciences (Switzerland), 14(5). https://doi.org/10.3390/app14052125 Kummer, S., & Kranz, D. C. (2022). Henipaviruses—A constant threat to livestock and humans. In PLoS Neglected Tropical Diseases (Vol. 16, Issue 2). https://doi.org/10.1371/journal.pntd.0010157 Kuzmin, I. V., Bozick, B., Guagliardo, S. A., Kunkel, R., Shak, J. R., Tong, S., & Rupprecht, C. E. (2011). Bats, emerging infectious diseases, and the rabies paradigm revisited. In Emerging Health Threats Journal (Vol. 4, Issue 1). https://doi.org/10.3402/ehtj.v4i0.7159 Lawson, E. T., Ayivor, J. S., Ohemeng, F., & Ntiamoa-Baidu, Y. (2019). Avoiding bites and scratches? Understanding the public health implication of human–bat interactions in Ghana. Zoonoses and Public Health, 66(1). https://doi.org/10.1111/zph.12540 Letko, M., Seifert, S. N., Olival, K. J., Plowright, R. K., & Munster, V. J. (2020). Bat-borne virus diversity, spillover and emergence. In Nature Reviews Microbiology (Vol. 18, Issue 8, pp. 461–471). Nature Research. https://doi.org/10.1038/s41579-020-0394-z MacLachlan, N. J., & Dubovi, E. J. (2017). Paramyxoviridae and Pneumoviridae. Fenner’s Veterinary Virology, 327–356. https://doi.org/10.1016/B978-0-12-800946-8.00017-9 Malta, L. (2017). Detección molecular de rhabdovirus y pneumovirus en murciélagos del Uruguay. Mendenhall, C. D., Karp, D. S., Meyer, C. F. J., Hadly, E. A., & Daily, G. C. (2014). Predicting biodiversity change and averting collapse in agricultural landscapes. Nature, 509(7499). https://doi.org/10.1038/nature13139 Moratelli, R., & Calisher, C. H. (2015). Bats and zoonotic viruses: Can we confidently link bats with emerging deadly viruses? Memorias Do Instituto Oswaldo Cruz, 110(1). https://doi.org/10.1590/0074-02760150048 Murillo-García, O. E., & Bedoya-Durán, M. J. (2014). Distribución y abundancia de murciélagos en bosques con diferente grado de intervención en el Parque Nacional Natural Gorgona (Colombia). Revista de Biología Tropical, 62. https://doi.org/10.15517/rbt.v62i0.16367 Nojiri, T., Wilson, L. A. B., López-Aguirre, C., Tu, V. T., Kuratani, S., Ito, K., Higashiyama, H., Son, N. T., Fukui, D., Sadier, A., Sears, K. E., Endo, H., Kamihori, S., & Koyabu, D. (2021). Embryonic evidence uncovers convergent origins of laryngeal echolocation in bats. Current Biology, 31(7). https://doi.org/10.1016/j.cub.2020.12.043 Peel, A. J., Wells, K., Giles, J., Boyd, V., Burroughs, A., Edson, D., Crameri, G., Baker, M. L., Field, H., Wang, L. F., McCallum, H., Plowright, R. K., & Clark, N. (2019). Synchronous shedding of multiple bat paramyxoviruses coincides with peak periods of Hendra virus spillover. Emerging Microbes and Infections, 8(1). https://doi.org/10.1080/22221751.2019.1661217 Quarleri, J., Galvan, V., & Delpino, M. V. (2022). Henipaviruses: an expanding global public health concern? GeroScience, 44(5). https://doi.org/10.1007/s11357-022-00670-9 Ramírez-Fráncel, L. A., García-Herrera, L. V., Losada-Prado, S., Reinoso-Flórez, G., Sánchez-Hernández, A., Estrada-Villegas, S., Lim, B. K., & Guevara, G. (2022). Bats and their vital ecosystem services: a global review. In Integrative Zoology (Vol. 17, Issue 1, pp. 2–23). John Wiley and Sons Inc. https://doi.org/10.1111/1749-4877.12552 Rima, B., Balkema-Buschmann, A., Dundon, W. G., Duprex, P., Easton, A., Fouchier, R., Kurath, G., Lamb, R., Lee, B., Rota, P., & Wang, L. (2019). ICTV Virus Taxonomy Profile: Paramyxoviridae. Journal of General Virology, 100(12). https://doi.org/10.1099/jgv.0.001328 Rizzo, F., Edenborough, K. M., Toffoli, R., Culasso, P., Zoppi, S., Dondo, A., Robetto, S., Rosati, S., Lander, A., Kurth, A., Orusa, R., Bertolotti, L., & Mandola, M. L. (2017). Coronavirus and paramyxovirus in bats from Northwest Italy. BMC Veterinary Research, 13(1). https://doi.org/10.1186/s12917-017-1307-x Rocha, R., Ovaskainen, O., López-Baucells, A., Farneda, F. Z., Sampaio, E. M., Bobrowiec, P. E. D., Cabeza, M., Palmeirim, J. M., & Meyer, C. F. J. (2018). Secondary forest regeneration benefits old-growth specialist bats in a fragmented tropical landscape. Scientific Reports, 8(1). https://doi.org/10.1038/s41598-018-21999-2 Sasaki, M., Setiyono, A., Handharyani, E., Rahmadani, I., Taha, S., Adiani, S., Subangkit, M., Sawa, H., Nakamura, I., & Kimura, T. (2012). Molecular detection of a novel paramyxovirus in fruit bats from Indonesia. Virology Journal, 9. https://doi.org/10.1186/1743-422X-9-240 Subudhi, S., Rapin, N., & Misra, V. (2019). Immune system modulation and viral persistence in bats: Understanding viral spillover. In Viruses (Vol. 11, Issue 2). https://doi.org/10.3390/v11020192 Tachack, E. B., Oviedo-Socarrás, T., Pastrana, M. O., Pérez-Cogollo, L. C., Benavides, Y. H., Pinto, C. R., & Garay, O. V. (2022). Status of gastrointestinal nematode infections and associated epidemiological factors in sheep from Córdoba, Colombia. Tropical Animal Health and Production, 54(3). https://doi.org/10.1007/s11250-022-03170-2 Tizzano, M. A. CAPÍTULO 5 Paramixovirus. Patogenicidad microbiana en Medicina Veterinaria, 61. Tong, S., Chern, S. W. W., Li, Y., Pallansch, M. A., & Anderson, L. J. (2008). Sensitive and broadly reactive reverse transcription-PCR assays to detect novel paramyxoviruses. Journal of Clinical Microbiology, 46(8). https://doi.org/10.1128/JCM.00192-08 Wang, L. F., & Anderson, D. E. (2019). Viruses in bats and potential spillover to animals and humans. In Current Opinion in Virology (Vol. 34). https://doi.org/10.1016/j.coviro.2018.12.007 Weatherman, S., Feldmann, H., & de Wit, E. (2018). Transmission of henipaviruses. In Current Opinion in Virology (Vol. 28). https://doi.org/10.1016/j.coviro.2017.09.004 Wells, H. (2016). Whole-Genome Sequencing And Phylogenetic Analysis Of Novel Paramyxoviruses Discovered In Bats From Brazil. Public Health Theses. https://elischolar.library.yale.edu/ysphtdl/1318 Wild, T. F. (2009). Henipaviruses: A new family of emerging Paramyxoviruses. In Pathologie Biologie (Vol. 57, Issue 2). https://doi.org/10.1016/j.patbio.2008.04.006 |
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Echeverri de la Hoz, Daniel MauricioMartínez Bravo, Caty MilenaGómez Navarro, NayerlysPérez Cogollo, Luis CarlosCalderón Rangel, Alfonso2025-09-03T16:31:21Z2025-09-03T16:31:21Z2025-09-02https://repositorio.unicordoba.edu.co/handle/ucordoba/9544Universidad de CórdobaRepositorio Universidad de Córdobahttps://repositorio.unicordoba.edu.co/Este estudio tuvo como objetivo detectar la presencia de paramyxovirus en murciélagos del departamento de Córdoba, Colombia. Se analizaron muestras de 100 individuos pertenecientes a 11 especies de la familia Phyllostomidae, recolectadas en zonas urbanas, periurbanas y rurales. Se emplearon técnicas de biología molecular, utilizando RT-PCR semianidada dirigida al gen L del virus. La detección se confirmó por electroforesis en gel de agarosa. Se identificó un caso positivo en una hembra adulta de Phyllostomus discolor capturada en una zona rural del municipio de Chimá. Esta especie, de hábitos omnívoros y amplia capacidad de movimiento, podría haber facilitado su exposición al virus en distintos entornos. A pesar de la baja frecuencia, este hallazgo representa el primer reporte de paramyxovirus en murciélagos en Colombia. Los resultados destacan la necesidad de fortalecer la vigilancia epidemiológica de virus emergentes en fauna silvestre, ampliar el esfuerzo de muestreo y aplicar herramientas moleculares más sensibles. Además, se sugiere explorar el rol ecológico de los murciélagos en la diseminación viral, especialmente en ecosistemas compartidos con otras especies como las aves migratorias.This study aimed to detect the presence of paramyxovirus in bats from the department of Córdoba, Colombia. Samples from 100 individuals belonging to 11 species of the Phyllostomidae family were analyzed, collected in urban, peri-urban, and rural areas. Molecular biology techniques were used, employing semi-nested RT-PCR targeting the L gene of the virus. Detection was confirmed by agarose gel electrophoresis. One positive case was identified in an adult female Phyllostomus discolor captured in a rural area of the municipality of Chimá. This species, with omnivorous habits and high mobility, could have facilitated its exposure to the virus in different environments. Despite the low frequency, this finding represents the first report of paramyxovirus in bats in Colombia. The results highlight the need to strengthen the epidemiological surveillance of emerging viruses in wildlife, expand sampling efforts, and apply more sensitive molecular tools. In addition, it is suggested to explore the ecological role of bats in viral dissemination, especially in ecosystems shared with other species such as migratory birds.1. Introducción .................132. Objetivos........................162.1 Objetivo general ...................................162.2 Objetivos específicos ..................................163. Marco Teórico.............................173.1 Murciélagos .....................................173.2 Murciélagos en el mantenimiento de virus .................183.3 Paramixovirus ...................203.3.1 Clasificación y Taxonomía....................203.3.2 Genoma y virión ……………..203.3.3 Sistema inmune del murciélago contra los paramixovirus ..........223.4 Antecedentes .......................223.4.1 Paramixovirus en murciélagos del viejo mundo..................223.4.2 Paramixovirus en murciélagos del nuevo mundo ............234. Metodología................................. 264.1 Localización .........................264.2 Tipo de estudio ...............................264.3 Componentes éticos.....................264.4 Procedimiento para la obtención de muestras..........264.5 Metodología para el cumplimiento del objetivo específico 2.2.1 ..... 274.5.1 Caracterización de la población de estudio ...............274.6 Metodología para el cumplimiento del objetivo específico 2.2.2 .............284.6.1 Extraccion de material genético................284.6.2 Detección molecular...................294.7 Metodología para el cumplimiento del objetivo específico 2.2.3 .....304.7.1 Distribución geográfica de los murciélagos positivos a paramixovirus….305. Resultados.......................315.1 Resultados relacionados con el cumplimiento del objetivo específico número 2.2.1..........................315.1.1 Caracterización de la población de estudio..............315.2 Resultados relacionados con el cumplimiento del objetivo específico número 2.2.2.......................................355.2.1 Extracción de material genético......................355.2.2 Detección molecular.........................355.3 Resultados relacionados con el cumplimiento del objetivo específico número 2.2.3.................................365.3.1 Distribución geográfica del murciélago positivo a paramixovirus......366. Discusión .................................397. Conclusiones ...................438. Recomendaciones..............................439. 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In Pathologie Biologie (Vol. 57, Issue 2). https://doi.org/10.1016/j.patbio.2008.04.006RT-PCRZoonosisFauna silvestreVigilancia epidemiológicaVirus emergentesRT-PCRZoonosisWildlifeEpidemiological SurveillanceEmerging virusesPublicationLICENSElicense.txtlicense.txttext/plain; charset=utf-815543https://dspace8-unicordoba.metabuscador.org/bitstreams/8c61d697-271c-47d7-88cd-f6feb8304afe/download73a5432e0b76442b22b026844140d683MD51falseAnonymousREADORIGINALGómezNavarroNayerlys.pdfGómezNavarroNayerlys.pdfapplication/pdf1937334https://dspace8-unicordoba.metabuscador.org/bitstreams/51e5c271-f96b-4071-adf5-d2cd21c0505b/download21cc6e5f092bc51add851b112f958cafMD53trueAnonymousREADFormato de autorización.pdfapplication/pdf649490https://dspace8-unicordoba.metabuscador.org/bitstreams/d53b9eb7-9a0d-4ffb-a2a1-4ee449335fcb/download20f244c50683ef6e17b2c3c1c0868414MD54falseTEXTGómezNavarroNayerlys.pdf.txtGómezNavarroNayerlys.pdf.txtExtracted 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03:01:15.788https://creativecommons.org/licenses/by-nc-nd/4.0/Copyright Universidad de Córdoba, 2025open.accesshttps://dspace8-unicordoba.metabuscador.orgRepositorio institucional Universidad de 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