Analisis De Longitud Telomérica En Pacientes Con Demencia Tipo Alzheimer En Colombia

Alzheimer's disease, a neurodegenerative disorder that mainly affects older people, has been linked to alterations in telomeric length, a structure that protects chromosomes. However, in Colombia, studies on telomeric length in the context of this disease are limited, since most research focuse...

Full description

Autores:
Arias Ovalle, Juan Andrés
Tipo de recurso:
Tesis
Fecha de publicación:
2024
Institución:
Universidad Antonio Nariño
Repositorio:
Repositorio UAN
Idioma:
spa
OAI Identifier:
oai:repositorio.uan.edu.co:123456789/12198
Acceso en línea:
https://repositorio.uan.edu.co/handle/123456789/12198
Palabra clave:
Longitud telomérica
Enfermedad de Alzheimer
Telómeros
Pacientes
Colombia
Telomere length
Alzheimer's disease
Telomeres
Patients
Colombia
MMQPCR
Rights
restrictedAccess
License
http://purl.org/coar/access_right/c_16ec
Description
Summary:Alzheimer's disease, a neurodegenerative disorder that mainly affects older people, has been linked to alterations in telomeric length, a structure that protects chromosomes. However, in Colombia, studies on telomeric length in the context of this disease are limited, since most research focuses on specific mutations. This work aimed to analyze the relationship between telomeric length and Alzheimer's disease in a sample of Colombian patients. We collected 39 peripheral blood samples from patients diagnosed with Alzheimer's disease and a control group, also evaluating factors such as age and gender of the participants. T