Effect of histone demethylation on differentiation of pancreatic beta cells derived from induced pluripotent cells
Diabetes mellitus is one of the most frequent causes of mortality in the world, and its close etiological relationship with obesity makes the increase in prevalence continuously higher, especially in developing countries. Diabetes mellitus consists of two main clinical pictures: type 1 diabetes mell...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2025
- Institución:
- Universidad de la Sabana
- Repositorio:
- Repositorio Universidad de la Sabana
- Idioma:
- eng
- OAI Identifier:
- oai:intellectum.unisabana.edu.co:10818/67059
- Acceso en línea:
- https://hdl.handle.net/10818/67059
- Palabra clave:
- Diabetes mellitus
Obesidad
Mortalidad
Prevalencia
Enfermedades crónicas no transmisibles
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional
| Summary: | Diabetes mellitus is one of the most frequent causes of mortality in the world, and its close etiological relationship with obesity makes the increase in prevalence continuously higher, especially in developing countries. Diabetes mellitus consists of two main clinical pictures: type 1 diabetes mellitus, characterized by the destruction of insulin-producing cells due to an autoimmune attack, and type 2 diabetes mellitus, in which the deterioration of insulin-producing pancreatic beta cells is partial, and insulin activity is impaired by resistance to its action in the tissues. Multiple therapeutic plans exist for chronic diabetes therapy, including subcutaneous insulin administration. However, the presence of cardiovascular complications means that the life expectancy and quality of life of diabetics are significantly impaired. |
|---|