Biologics in covid 19 so far ¿scoping review¿

31 páginas

Autores:
Arias González, Milton Eduardo
Tipo de recurso:
Trabajo de grado de pregrado
Fecha de publicación:
2021
Institución:
Universidad de la Sabana
Repositorio:
Repositorio Universidad de la Sabana
Idioma:
spa
OAI Identifier:
oai:intellectum.unisabana.edu.co:10818/50269
Acceso en línea:
https://hdl.handle.net/10818/50269
Palabra clave:
COVID-19
Productos biológicos
Biofarmacéutica
Interferón
Células madre mesenquimales
Rights
License
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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dc.title.es_CO.fl_str_mv Biologics in covid 19 so far ¿scoping review¿
title Biologics in covid 19 so far ¿scoping review¿
spellingShingle Biologics in covid 19 so far ¿scoping review¿
COVID-19
Productos biológicos
Biofarmacéutica
Interferón
Células madre mesenquimales
title_short Biologics in covid 19 so far ¿scoping review¿
title_full Biologics in covid 19 so far ¿scoping review¿
title_fullStr Biologics in covid 19 so far ¿scoping review¿
title_full_unstemmed Biologics in covid 19 so far ¿scoping review¿
title_sort Biologics in covid 19 so far ¿scoping review¿
dc.creator.fl_str_mv Arias González, Milton Eduardo
dc.contributor.advisor.none.fl_str_mv Bustos Cruz, Rosa Helena
Oliveros, Henry
dc.contributor.author.none.fl_str_mv Arias González, Milton Eduardo
dc.subject.armarc.es_CO.fl_str_mv COVID-19
Productos biológicos
Biofarmacéutica
Interferón
Células madre mesenquimales
topic COVID-19
Productos biológicos
Biofarmacéutica
Interferón
Células madre mesenquimales
description 31 páginas
publishDate 2021
dc.date.issued.none.fl_str_mv 2021-11-11
dc.date.accessioned.none.fl_str_mv 2022-04-01T13:45:12Z
dc.date.available.none.fl_str_mv 2022-04-01T13:45:12Z
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dc.publisher.es_CO.fl_str_mv Universidad de La Sabana
dc.source.es_CO.fl_str_mv Universidad de La Sabana
Intellectum Repositorio Universidad de La Sabana
institution Universidad de la Sabana
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spelling Bustos Cruz, Rosa HelenaOliveros, HenryArias González, Milton Eduardo2022-04-01T13:45:12Z2022-04-01T13:45:12Z2021-11-11https://hdl.handle.net/10818/50269284975TE1162510.3390/xxxxx31 páginasThis scoping review aimed to evaluate the available evidence of the use of Biologics as treat-ment candidates for the treatment of severe and advanced COVID¿19 disease; what are the ra-tionale for their use, which are the most studied, and what kind of efficacy measures are de-scribed. A search through Cochrane, Embase, Pubmed, Medline, medrxiv.org and Google schol-ar was performed, on the use of biologic interventions in the COVID¿19/ SARS-COV-2 infection, viral pneumonia, and sepsis, until July 31, 2021. Throughout the research, we identified 4260 records of which 84 were selected for qualitative analysis. Amongst the results, we identified 5 popular targets of use: IL6 and IL1 inhibitors, Janus Kinase inhibitors, interferons, and mesen-chymal stem cells treatment. None of them offered conclusive evidence of their efficacy with consistency and statistical significance; however, Il6 and IL1 inhibitors, as well as interferons show encouraging data in terms of increased survival and favorable clinical course that require further studies with better methodology standardization.application/pdfspaUniversidad de La SabanaAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaBiologics in covid 19 so far ¿scoping review¿Tesis/Trabajo de grado - Especializaciónhttp://purl.org/coar/resource_type/c_7a1fTextoinfo:eu-repo/semantics/otherhttp://purl.org/redcol/resource_type/COtherinfo:eu-repo/semantics/acceptedVersionCOVID-19Productos biológicosBiofarmacéuticaInterferónCélulas madre mesenquimalesFacultad de MedicinaEspecialización en Farmacología ClínicaEspecialista en Farmacología ClínicaPublicationLICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstreams/fbb01ada-d39c-42ed-b2c8-bd0166c1e506/downloadf52a2cfd4df262e08e9b300d62c85cabMD53falseAnonymousREADconsentimiento de biblioteca.pdfconsentimiento de biblioteca.pdfCartaapplication/pdf154536https://intellectum.unisabana.edu.co/bitstreams/2219d1b6-7263-4018-b190-9fa85418731f/downloadfadbf98c31ce7768ef0c55a37c5dc4a8MD54falseAdministratorREADTEXTV3. Biologics in covid 19 so far ¿scoping review¿[16120] (1).pdf.txtV3. Biologics in covid 19 so far ¿scoping review¿[16120] (1).pdf.txtExtracted texttext/plain101389https://intellectum.unisabana.edu.co/bitstreams/007bbf4c-011d-4aac-8d93-50db9f36822f/download39403207b06435d7c421ac4f071d7616MD55falseAnonymousREADORIGINALV3. Biologics in covid 19 so far ¿scoping review¿[16120] (1).pdfV3. Biologics in covid 19 so far ¿scoping review¿[16120] (1).pdfVer documento en PDFapplication/pdf738645https://intellectum.unisabana.edu.co/bitstreams/4db60992-4476-439c-95cc-32556b26283e/download3a66b369c84f6f701239901ca49b8336MD51trueAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstreams/0de814ba-fc0d-4c62-a022-9a8e4440f5fe/download4460e5956bc1d1639be9ae6146a50347MD52falseAnonymousREADTHUMBNAILV3. Biologics in covid 19 so far ¿scoping review¿[16120] (1).pdf.jpgV3. Biologics in covid 19 so far ¿scoping review¿[16120] (1).pdf.jpgGenerated Thumbnailimage/jpeg15155https://intellectum.unisabana.edu.co/bitstreams/b9928291-5f3f-4acd-b17c-14be4b009cd4/downloade93f14622c84f695e9f0c47124c73c14MD56falseAnonymousREAD10818/50269oai:intellectum.unisabana.edu.co:10818/502692025-12-11 13:02:32.618http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internacionalopen.accesshttps://intellectum.unisabana.edu.coIntellectum Repositorio Universidad de La Sabanacontactointellectum@unisabana.edu.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