Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare
62 Páginas.
- Autores:
-
Ramírez Rodríguez, Laura Cristina
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2017
- Institución:
- Universidad de la Sabana
- Repositorio:
- Repositorio Universidad de la Sabana
- Idioma:
- spa
- OAI Identifier:
- oai:intellectum.unisabana.edu.co:10818/30085
- Acceso en línea:
- https://hdl.handle.net/10818/30085
- Palabra clave:
- Bacterias
Agentes antibacteriales
Extracción (Química)
Compuestos bioactivos
Química farmacéutica
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International
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Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare |
| title |
Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare |
| spellingShingle |
Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare Bacterias Agentes antibacteriales Extracción (Química) Compuestos bioactivos Química farmacéutica |
| title_short |
Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare |
| title_full |
Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare |
| title_fullStr |
Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare |
| title_full_unstemmed |
Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare |
| title_sort |
Obtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río Guaviare |
| dc.creator.fl_str_mv |
Ramírez Rodríguez, Laura Cristina |
| dc.contributor.advisor.none.fl_str_mv |
Díaz Barrera, Luis Eduardo |
| dc.contributor.author.none.fl_str_mv |
Ramírez Rodríguez, Laura Cristina |
| dc.subject.none.fl_str_mv |
Bacterias Agentes antibacteriales Extracción (Química) Compuestos bioactivos Química farmacéutica |
| topic |
Bacterias Agentes antibacteriales Extracción (Química) Compuestos bioactivos Química farmacéutica |
| description |
62 Páginas. |
| publishDate |
2017 |
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2017-04-04T23:10:23Z |
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2017-04-04T23:10:23Z |
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2017 |
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2017-04-04 |
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Tesis/Trabajo de grado - Pregrado |
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Abd-Elnaby, Hanan M., Gehan M. Abo-Elala, Usama M. Abdel-Raouf, and Moaz M. Hamed. 2016. ¿Antibacterial and Anticancer Activity of Extracellular Synthesized Silver Nanoparticles from Marine Streptomyces Rochei MHM13.¿ The Egyptian Journal of Aquatic Research 42(3): 301¿12. Alapati, Kavitha, and Muvva Vijayalakshmi. 2013. ¿Evaluation of Bioactive Compounds Produced by Nocardia Levis MK-VL_113 & Streptomyces Tendae TK-VL_333 for Cytotoxic Activity.¿ The Indian Journal of Medical Research 137 (2)(February): 391¿93. Almagro, M C, and D Vucic. 2012. ¿The Inhibitor of Apoptosis (Iap) Proteins Are Critical Regulators of Signaling Pathways and Targets for Anti-Cancer Therapy.¿ Experimental Oncology 34: 200¿211. Astudillo, M et al. 2011. ¿Percepciones Sobre El Cáncer de Próstata En Población Masculina Mayor de 45 Años. Santa Rosa de Cabal.¿ Hacia la Promoción de la Salud 16(2): 147¿61. Balachandran, C et al. 2014. ¿A Flavonoid Isolated from Streptomyces Sp. (ERINLG- 4) Induces Apoptosis in Human Lung Cancer A549 Cells through p53 and Cytochrome c Release Caspase Dependant Pathway.¿ Chemico-Biological Interactions 224: 24¿35. http://dx.doi.org/10.1016/j.cbi.2014.09.019. Balachandran, C. et al. 2016. ¿Isolation and Characterization of 2-Hydroxy-9,10- Anthraquinone from Streptomyces Olivochromogenes (ERINLG-261) with Antimicrobial and Antiproliferative Properties.¿ Revista Brasileira de Farmacognosia 26(3): 1¿11. http://linkinghub.elsevier.com/retrieve/pii/S0102695X16000028. Balachandran, C., V Duraipandiyan, and S Ignacimuthu. 2012. ¿Purification and Characterization of Protease Enzyme from Actinomycetes and Its Cytotoxic Effect on Cancer Cell Line (A549).¿ Asian Pacific Journal of Tropical Biomedicine 2(2 SUPPL.): 392¿400. Barnard, Romain L, Catherine A Osborne, and Mary K Firestone. 2013. ¿Responses of Soil Bacterial and Fungal Communities to Extreme Desiccation and Rewetting.¿ The ISME Journal 7(11): 2229¿41. http://www.nature.com/doifinder/10.1038/ismej.2013.104 (October 3, 2016). Castillo, Epifanio et al. 2001. ¿Efectividad de Actinomicetos Aislados de La Rizosfera de Papa Sobre Rhizoctonia Solani Khun in Vitro.¿ Revista Mexicana de Fitopatologia 22: 203¿7. Chauhan, Ranchan et al. 2017. ¿Experimental Investigation and Optimization of Impinging Jet Solar Thermal Collector by Taguchi Method.¿ Applied Thermal Engineering 116: 100¿109. http://linkinghub.elsevier.com/retrieve/pii/S1359431117301540 (March 17, Dzeng, Richard K et al. 2015. ¿Small Molecule Growth Inhibitors of Human Oncogenic Gammaherpesvirus Infected B-Cells.¿ Molecular Oncology 9(2): 365¿ 76. http://doi.wiley.com/10.1016/j.molonc.2014.09.006 (March 16, 2017). Fitzmaurice, Christina, Daniel Dicker, Amanda Pain, and Hannah Hamavid. 2015. ¿The Global Burden of Cancer 2013.¿ JAMA Oncology 1(4): 505. http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jamaoncol.2015.073 5 (August 25, 2016). Forner, David et al. 2013. ¿Chemical Dereplication of Marine Actinomycetes by Liquid Chromatography¿high Resolution Mass Spectrometry Profiling and Statistical Analysis.¿ Analytica Chimica Acta 805: 70¿79. http://www.ncbi.nlm.nih.gov/pubmed/24296145 (March 17, 2017). Francois, Denizot, and Rita Lang. 1986. ¿Rapid Colorimetric Assay for Cell Growth and Survival.¿ Journal of lmmunological Methods 89: 271¿77. Gaviria, Ana Milena, Stefano Vinaccia, María Fernanda Riveros, and Japcy Margarita Quiceno. 2007. ¿Calidad de Vida Relacionada Con La Salud , Afrontamiento Del Estrés Y Emociones Negativas En Pacientes Con Cáncer En Tratamiento Quimioterapéutico.¿ Psicologia desde el Caribe 20: 50¿75 Gomathi, Ajitha, and K Gothandam. 2016. ¿Ocean Dwelling Actinobacteria as Source of Antitumor Compounds.¿ 59(December): 1¿21. Gorajana, Adinarayana et al. 2007. ¿Resistoflavine, Cytotoxic Compound from a Marine Actinomycete, Streptomyces Chibaensis AUBN1/7.¿ Microbiological Research 162(4): 322¿27. http://linkinghub.elsevier.com/retrieve/pii/S0944501306000140 Han, Ying et al. 2016. ¿Halichoblelide D, a New Elaiophylin Derivative with Potent Cytotoxic Activity from Mangrove-Derived Streptomyces Sp. 219807.¿ Molecules 21(8). Harzevili, Farshad Darvishi, and Hongzhang Chen. 2014. Microbial Biotechnology¿: Progress and Trends. Heald, S C, P F Brandão, R Hardicre, and A T Bull. 2001. ¿Physiology, Biochemistry and Taxonomy of Deep-Sea Nitrile Metabolising Rhodococcus Strains.¿ Antonie van Leeuwenhoek 80(2): 169¿83. http://www.ncbi.nlm.nih.gov/pubmed/11759050 (October 3, 2016). Hooi Leng, Ser et al. 2015. ¿Evaluation of Antioxidative and Cytotoxic Activities of Streptomyces Pluripotens MUSC 137 Isolated from Mangrove Soil in Malaysia.¿ Frontiers in Microbiology 6(DEC): 1¿11. Hopwood, DA et al. 1986. Genetic Manipulation of Streptomyces. Jemimah, Naine S, Devi C Subathra, V. Mohanasrinivasan, and B. Vaishnavi. 2015. ¿Antimicrobial, Antioxidant and Cytotoxic Activity of Marine Streptomyces Parvulus VITJS11 Crude Extract.¿ Brazilian Archives of Biology and Technology 58(2): 198¿207. Jiao, Wence et al. 2013. ¿A Novel Alkaloid from Marine-Derived Actinomycete Streptomyces Xinghaiensis with Broad-Spectrum Antibacterial and Cytotoxic Activities.¿ PLoS ONE 8(10): 230¿38. Jung, Da Un et al. 2014. ¿Optimization of Medium Composition for Enhanced Cellulase Production by Mutant Penicillium Brasilianum KUEB15 Using Statistical Method.¿ Journal of Industrial and Engineering Chemistry 25: Pages 145¿150 Karuppiah, Valliappan, Chandramohan Aarthi, Kannan Sivakumar, and Lakshmanan Kannan. 2013. ¿Statistical Optimization and Anticancer Activity of a Red Pigment Isolated from Streptomyces Sp. PM4.¿ Asian Pacific Journal of Tropical Biomedicine 3(8): 650¿56. Kizhakkedathu, Niladevi, Jacob Nicemol, and Prema Parukuttyamma. 2008. ¿Evidence for a Halotolerant-Alkaline Laccase in Streptomyces Psammoticus: Purification and Characterization.¿ Process Biochemistry 43(6): 654¿60. Korzybski, Tadeusz, Zuzanna Kowszyk-Gindifer, W¿odzimierz Kury¿owicz, and Edwin Paryski. 1967. Antibiotics. Volume 1¿: Origin, Nature and Properties. Lara, Rodrigo. 2015. ¿Cáncer de Próstata Continúa En Aumento En Colombia.¿ El Espectador: 1. http://www.elespectador.com/noticias/salud/cancer-de-prostatacontinua-aumento-colombia-articulo-593026. |
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Abd-Elnaby, Hanan M., Gehan M. Abo-Elala, Usama M. Abdel-Raouf, and Moaz M. Hamed. 2016. ¿Antibacterial and Anticancer Activity of Extracellular Synthesized Silver Nanoparticles from Marine Streptomyces Rochei MHM13.¿ The Egyptian Journal of Aquatic Research 42(3): 301¿12. Alapati, Kavitha, and Muvva Vijayalakshmi. 2013. ¿Evaluation of Bioactive Compounds Produced by Nocardia Levis MK-VL_113 & Streptomyces Tendae TK-VL_333 for Cytotoxic Activity.¿ The Indian Journal of Medical Research 137 (2)(February): 391¿93. Almagro, M C, and D Vucic. 2012. ¿The Inhibitor of Apoptosis (Iap) Proteins Are Critical Regulators of Signaling Pathways and Targets for Anti-Cancer Therapy.¿ Experimental Oncology 34: 200¿211. Astudillo, M et al. 2011. ¿Percepciones Sobre El Cáncer de Próstata En Población Masculina Mayor de 45 Años. Santa Rosa de Cabal.¿ Hacia la Promoción de la Salud 16(2): 147¿61. Balachandran, C et al. 2014. ¿A Flavonoid Isolated from Streptomyces Sp. (ERINLG- 4) Induces Apoptosis in Human Lung Cancer A549 Cells through p53 and Cytochrome c Release Caspase Dependant Pathway.¿ Chemico-Biological Interactions 224: 24¿35. http://dx.doi.org/10.1016/j.cbi.2014.09.019. Balachandran, C. et al. 2016. ¿Isolation and Characterization of 2-Hydroxy-9,10- Anthraquinone from Streptomyces Olivochromogenes (ERINLG-261) with Antimicrobial and Antiproliferative Properties.¿ Revista Brasileira de Farmacognosia 26(3): 1¿11. http://linkinghub.elsevier.com/retrieve/pii/S0102695X16000028. Balachandran, C., V Duraipandiyan, and S Ignacimuthu. 2012. ¿Purification and Characterization of Protease Enzyme from Actinomycetes and Its Cytotoxic Effect on Cancer Cell Line (A549).¿ Asian Pacific Journal of Tropical Biomedicine 2(2 SUPPL.): 392¿400. Barnard, Romain L, Catherine A Osborne, and Mary K Firestone. 2013. ¿Responses of Soil Bacterial and Fungal Communities to Extreme Desiccation and Rewetting.¿ The ISME Journal 7(11): 2229¿41. http://www.nature.com/doifinder/10.1038/ismej.2013.104 (October 3, 2016). Castillo, Epifanio et al. 2001. ¿Efectividad de Actinomicetos Aislados de La Rizosfera de Papa Sobre Rhizoctonia Solani Khun in Vitro.¿ Revista Mexicana de Fitopatologia 22: 203¿7. Chauhan, Ranchan et al. 2017. ¿Experimental Investigation and Optimization of Impinging Jet Solar Thermal Collector by Taguchi Method.¿ Applied Thermal Engineering 116: 100¿109. http://linkinghub.elsevier.com/retrieve/pii/S1359431117301540 (March 17, Dzeng, Richard K et al. 2015. ¿Small Molecule Growth Inhibitors of Human Oncogenic Gammaherpesvirus Infected B-Cells.¿ Molecular Oncology 9(2): 365¿ 76. http://doi.wiley.com/10.1016/j.molonc.2014.09.006 (March 16, 2017). Fitzmaurice, Christina, Daniel Dicker, Amanda Pain, and Hannah Hamavid. 2015. ¿The Global Burden of Cancer 2013.¿ JAMA Oncology 1(4): 505. http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jamaoncol.2015.073 5 (August 25, 2016). Forner, David et al. 2013. ¿Chemical Dereplication of Marine Actinomycetes by Liquid Chromatography¿high Resolution Mass Spectrometry Profiling and Statistical Analysis.¿ Analytica Chimica Acta 805: 70¿79. http://www.ncbi.nlm.nih.gov/pubmed/24296145 (March 17, 2017). Francois, Denizot, and Rita Lang. 1986. ¿Rapid Colorimetric Assay for Cell Growth and Survival.¿ Journal of lmmunological Methods 89: 271¿77. Gaviria, Ana Milena, Stefano Vinaccia, María Fernanda Riveros, and Japcy Margarita Quiceno. 2007. ¿Calidad de Vida Relacionada Con La Salud , Afrontamiento Del Estrés Y Emociones Negativas En Pacientes Con Cáncer En Tratamiento Quimioterapéutico.¿ Psicologia desde el Caribe 20: 50¿75 Gomathi, Ajitha, and K Gothandam. 2016. ¿Ocean Dwelling Actinobacteria as Source of Antitumor Compounds.¿ 59(December): 1¿21. Gorajana, Adinarayana et al. 2007. ¿Resistoflavine, Cytotoxic Compound from a Marine Actinomycete, Streptomyces Chibaensis AUBN1/7.¿ Microbiological Research 162(4): 322¿27. http://linkinghub.elsevier.com/retrieve/pii/S0944501306000140 Han, Ying et al. 2016. ¿Halichoblelide D, a New Elaiophylin Derivative with Potent Cytotoxic Activity from Mangrove-Derived Streptomyces Sp. 219807.¿ Molecules 21(8). Harzevili, Farshad Darvishi, and Hongzhang Chen. 2014. Microbial Biotechnology¿: Progress and Trends. Heald, S C, P F Brandão, R Hardicre, and A T Bull. 2001. ¿Physiology, Biochemistry and Taxonomy of Deep-Sea Nitrile Metabolising Rhodococcus Strains.¿ Antonie van Leeuwenhoek 80(2): 169¿83. http://www.ncbi.nlm.nih.gov/pubmed/11759050 (October 3, 2016). Hooi Leng, Ser et al. 2015. ¿Evaluation of Antioxidative and Cytotoxic Activities of Streptomyces Pluripotens MUSC 137 Isolated from Mangrove Soil in Malaysia.¿ Frontiers in Microbiology 6(DEC): 1¿11. Hopwood, DA et al. 1986. Genetic Manipulation of Streptomyces. Jemimah, Naine S, Devi C Subathra, V. Mohanasrinivasan, and B. Vaishnavi. 2015. ¿Antimicrobial, Antioxidant and Cytotoxic Activity of Marine Streptomyces Parvulus VITJS11 Crude Extract.¿ Brazilian Archives of Biology and Technology 58(2): 198¿207. Jiao, Wence et al. 2013. ¿A Novel Alkaloid from Marine-Derived Actinomycete Streptomyces Xinghaiensis with Broad-Spectrum Antibacterial and Cytotoxic Activities.¿ PLoS ONE 8(10): 230¿38. Jung, Da Un et al. 2014. ¿Optimization of Medium Composition for Enhanced Cellulase Production by Mutant Penicillium Brasilianum KUEB15 Using Statistical Method.¿ Journal of Industrial and Engineering Chemistry 25: Pages 145¿150 Karuppiah, Valliappan, Chandramohan Aarthi, Kannan Sivakumar, and Lakshmanan Kannan. 2013. ¿Statistical Optimization and Anticancer Activity of a Red Pigment Isolated from Streptomyces Sp. PM4.¿ Asian Pacific Journal of Tropical Biomedicine 3(8): 650¿56. Kizhakkedathu, Niladevi, Jacob Nicemol, and Prema Parukuttyamma. 2008. ¿Evidence for a Halotolerant-Alkaline Laccase in Streptomyces Psammoticus: Purification and Characterization.¿ Process Biochemistry 43(6): 654¿60. Korzybski, Tadeusz, Zuzanna Kowszyk-Gindifer, W¿odzimierz Kury¿owicz, and Edwin Paryski. 1967. Antibiotics. Volume 1¿: Origin, Nature and Properties. Lara, Rodrigo. 2015. ¿Cáncer de Próstata Continúa En Aumento En Colombia.¿ El Espectador: 1. http://www.elespectador.com/noticias/salud/cancer-de-prostatacontinua-aumento-colombia-articulo-593026. 264049 TE09020 |
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Díaz Barrera, Luis EduardoRamírez Rodríguez, Laura CristinaIngeniero Químico2017-04-04T23:10:23Z2017-04-04T23:10:23Z20172017-04-04Abd-Elnaby, Hanan M., Gehan M. Abo-Elala, Usama M. Abdel-Raouf, and Moaz M. Hamed. 2016. ¿Antibacterial and Anticancer Activity of Extracellular Synthesized Silver Nanoparticles from Marine Streptomyces Rochei MHM13.¿ The Egyptian Journal of Aquatic Research 42(3): 301¿12.Alapati, Kavitha, and Muvva Vijayalakshmi. 2013. ¿Evaluation of Bioactive Compounds Produced by Nocardia Levis MK-VL_113 & Streptomyces Tendae TK-VL_333 for Cytotoxic Activity.¿ The Indian Journal of Medical Research 137 (2)(February): 391¿93.Almagro, M C, and D Vucic. 2012. ¿The Inhibitor of Apoptosis (Iap) Proteins Are Critical Regulators of Signaling Pathways and Targets for Anti-Cancer Therapy.¿ Experimental Oncology 34: 200¿211.Astudillo, M et al. 2011. ¿Percepciones Sobre El Cáncer de Próstata En Población Masculina Mayor de 45 Años. Santa Rosa de Cabal.¿ Hacia la Promoción de la Salud 16(2): 147¿61.Balachandran, C et al. 2014. ¿A Flavonoid Isolated from Streptomyces Sp. (ERINLG- 4) Induces Apoptosis in Human Lung Cancer A549 Cells through p53 and Cytochrome c Release Caspase Dependant Pathway.¿ Chemico-Biological Interactions 224: 24¿35. http://dx.doi.org/10.1016/j.cbi.2014.09.019.Balachandran, C. et al. 2016. ¿Isolation and Characterization of 2-Hydroxy-9,10- Anthraquinone from Streptomyces Olivochromogenes (ERINLG-261) with Antimicrobial and Antiproliferative Properties.¿ Revista Brasileira de Farmacognosia 26(3): 1¿11. http://linkinghub.elsevier.com/retrieve/pii/S0102695X16000028.Balachandran, C., V Duraipandiyan, and S Ignacimuthu. 2012. ¿Purification and Characterization of Protease Enzyme from Actinomycetes and Its Cytotoxic Effect on Cancer Cell Line (A549).¿ Asian Pacific Journal of Tropical Biomedicine 2(2 SUPPL.): 392¿400.Barnard, Romain L, Catherine A Osborne, and Mary K Firestone. 2013. ¿Responses of Soil Bacterial and Fungal Communities to Extreme Desiccation and Rewetting.¿ The ISME Journal 7(11): 2229¿41. http://www.nature.com/doifinder/10.1038/ismej.2013.104 (October 3, 2016).Castillo, Epifanio et al. 2001. ¿Efectividad de Actinomicetos Aislados de La Rizosfera de Papa Sobre Rhizoctonia Solani Khun in Vitro.¿ Revista Mexicana de Fitopatologia 22: 203¿7.Chauhan, Ranchan et al. 2017. ¿Experimental Investigation and Optimization of Impinging Jet Solar Thermal Collector by Taguchi Method.¿ Applied Thermal Engineering 116: 100¿109. http://linkinghub.elsevier.com/retrieve/pii/S1359431117301540 (March 17,Dzeng, Richard K et al. 2015. ¿Small Molecule Growth Inhibitors of Human Oncogenic Gammaherpesvirus Infected B-Cells.¿ Molecular Oncology 9(2): 365¿ 76. http://doi.wiley.com/10.1016/j.molonc.2014.09.006 (March 16, 2017).Fitzmaurice, Christina, Daniel Dicker, Amanda Pain, and Hannah Hamavid. 2015. ¿The Global Burden of Cancer 2013.¿ JAMA Oncology 1(4): 505. http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jamaoncol.2015.073 5 (August 25, 2016).Forner, David et al. 2013. ¿Chemical Dereplication of Marine Actinomycetes by Liquid Chromatography¿high Resolution Mass Spectrometry Profiling and Statistical Analysis.¿ Analytica Chimica Acta 805: 70¿79. http://www.ncbi.nlm.nih.gov/pubmed/24296145 (March 17, 2017).Francois, Denizot, and Rita Lang. 1986. ¿Rapid Colorimetric Assay for Cell Growth and Survival.¿ Journal of lmmunological Methods 89: 271¿77.Gaviria, Ana Milena, Stefano Vinaccia, María Fernanda Riveros, and Japcy Margarita Quiceno. 2007. ¿Calidad de Vida Relacionada Con La Salud , Afrontamiento Del Estrés Y Emociones Negativas En Pacientes Con Cáncer En Tratamiento Quimioterapéutico.¿ Psicologia desde el Caribe 20: 50¿75Gomathi, Ajitha, and K Gothandam. 2016. ¿Ocean Dwelling Actinobacteria as Source of Antitumor Compounds.¿ 59(December): 1¿21.Gorajana, Adinarayana et al. 2007. ¿Resistoflavine, Cytotoxic Compound from a Marine Actinomycete, Streptomyces Chibaensis AUBN1/7.¿ Microbiological Research 162(4): 322¿27. http://linkinghub.elsevier.com/retrieve/pii/S0944501306000140Han, Ying et al. 2016. ¿Halichoblelide D, a New Elaiophylin Derivative with Potent Cytotoxic Activity from Mangrove-Derived Streptomyces Sp. 219807.¿ Molecules 21(8).Harzevili, Farshad Darvishi, and Hongzhang Chen. 2014. Microbial Biotechnology¿: Progress and Trends.Heald, S C, P F Brandão, R Hardicre, and A T Bull. 2001. ¿Physiology, Biochemistry and Taxonomy of Deep-Sea Nitrile Metabolising Rhodococcus Strains.¿ Antonie van Leeuwenhoek 80(2): 169¿83. http://www.ncbi.nlm.nih.gov/pubmed/11759050 (October 3, 2016).Hooi Leng, Ser et al. 2015. ¿Evaluation of Antioxidative and Cytotoxic Activities of Streptomyces Pluripotens MUSC 137 Isolated from Mangrove Soil in Malaysia.¿ Frontiers in Microbiology 6(DEC): 1¿11.Hopwood, DA et al. 1986. Genetic Manipulation of Streptomyces.Jemimah, Naine S, Devi C Subathra, V. Mohanasrinivasan, and B. Vaishnavi. 2015. ¿Antimicrobial, Antioxidant and Cytotoxic Activity of Marine Streptomyces Parvulus VITJS11 Crude Extract.¿ Brazilian Archives of Biology and Technology 58(2): 198¿207.Jiao, Wence et al. 2013. ¿A Novel Alkaloid from Marine-Derived Actinomycete Streptomyces Xinghaiensis with Broad-Spectrum Antibacterial and Cytotoxic Activities.¿ PLoS ONE 8(10): 230¿38.Jung, Da Un et al. 2014. ¿Optimization of Medium Composition for Enhanced Cellulase Production by Mutant Penicillium Brasilianum KUEB15 Using Statistical Method.¿ Journal of Industrial and Engineering Chemistry 25: Pages 145¿150Karuppiah, Valliappan, Chandramohan Aarthi, Kannan Sivakumar, and Lakshmanan Kannan. 2013. ¿Statistical Optimization and Anticancer Activity of a Red Pigment Isolated from Streptomyces Sp. PM4.¿ Asian Pacific Journal of Tropical Biomedicine 3(8): 650¿56.Kizhakkedathu, Niladevi, Jacob Nicemol, and Prema Parukuttyamma. 2008. ¿Evidence for a Halotolerant-Alkaline Laccase in Streptomyces Psammoticus: Purification and Characterization.¿ Process Biochemistry 43(6): 654¿60.Korzybski, Tadeusz, Zuzanna Kowszyk-Gindifer, W¿odzimierz Kury¿owicz, and Edwin Paryski. 1967. Antibiotics. Volume 1¿: Origin, Nature and Properties.Lara, Rodrigo. 2015. ¿Cáncer de Próstata Continúa En Aumento En Colombia.¿ El Espectador: 1. http://www.elespectador.com/noticias/salud/cancer-de-prostatacontinua-aumento-colombia-articulo-593026.https://hdl.handle.net/10818/30085264049TE0902062 Páginas.¿Las Actinobacterias son bacterias Gram positivas, filamentosas, de los 22500 compuestos bioactivos producidos por microbios el 45% son de Actinobacterias. Muchos de estos compuestos se han usado para el tratamiento de algunas enfermedades, como agentes antiinflamatorios, antituberculosos, antioxidantes y antineoplásicos, tales como: daunorrubicina, dactinomicina y mitomicina. El propósito del presente estudio fue evaluar la actividad citotóxica de extractos de Actinobacterias de los sedimentos de la ribera del río Guaviare 2°36'19.2"N 72°42'26.2"W (Colombia), para lo cual se escogieron 25 aislados que presentaron previa actividad antiquórum sensing (C. violaceum ATCC® 31532), antibacterial (E. coli ATCC® 23724, S. aureus ATCC® 25923, A. baumannii ATCC® 19606 y B. subtilis ATCC® 21556) y/o antifúngica (T. harzianum ATCC® 52443, Fusarium sp y C. gloeosporioides (aislados de desechos agrícolas). Los aislados fueron cultivados en ISP2 por siete días a 30ºC y 200 rpm y sometidas a procesos de extracción con acetato de etilo. Los extractos fueron preparados en soluciones stock (1mg/mL) disolviéndolos en medio DMEM y posteriormente empleados en ensayos de citotoxicidad mediante la técnica de MTT. Las líneas celulares estudiadas fueron: PC3 ATCC® CRL-7934 (cáncer de próstata), MDA ATCC® HTB-24 (cáncer de seno) y A549 ATCC® CCL-185 (cáncer de pulmón) y como control de línea no transformada se empleó la línea celular L-929 ATCC® CRL-6364 (fibroblastos de ratón).spaUniversidad de La SabanaIngeniería QuímicaFacultad de IngenieríaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_16ecUniversidad de La SabanaIntellectum Repositorio Universidad de La SabanaBacteriasAgentes antibacterialesExtracción (Química)Compuestos bioactivosQuímica farmacéuticaObtención de extractos con actividad citotoxica in vitro a partir de actinobacterias aisladas de sedimentos del río GuaviareTesis/Trabajo de grado - Pregradohttp://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/version/c_970fb48d4fbd8a85Textoinfo:eu-repo/semantics/bachelorThesishttp://purl.org/redcol/resource_type/TPPublicationORIGINALLaura Cristina Ramírez Rodríguez (Tesis).pdfLaura Cristina Ramírez Rodríguez (Tesis).pdfVer documento en PDFapplication/pdf2078902https://intellectum.unisabana.edu.co/bitstreams/7bdf9f62-c581-52b7-e053-7e0910accd73/download1cdb0c731b33e488b8ecf968258a5e51MD51trueCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81223https://intellectum.unisabana.edu.co/bitstreams/7bdf9f62-c753-52b7-e053-7e0910accd73/download7c9ab7f006165862d8ce9ac5eac01552MD52falseAdministratorREADAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstreams/7bdf9f62-c754-52b7-e053-7e0910accd73/downloadf52a2cfd4df262e08e9b300d62c85cabMD53falseAdministratorREADAnonymousREADLaura Cristina Ramírez Rodríguez (Carta).pdfLaura Cristina Ramírez Rodríguez (Carta).pdfapplication/pdf418266https://intellectum.unisabana.edu.co/bitstreams/7bdf9f62-c755-52b7-e053-7e0910accd73/downloaddaa49025f430eb1a73d1a54bf885780aMD54falseTEXTLaura Cristina Ramírez Rodríguez (Tesis).pdf.txtLaura Cristina Ramírez Rodríguez (Tesis).pdf.txtExtracted Texttext/plain132403https://intellectum.unisabana.edu.co/bitstreams/7bdf9f62-c689-52b7-e053-7e0910accd73/downloadb407303269bd4dbbf29eb18b3f570a21MD55falseTHUMBNAILLaura Cristina Ramírez Rodríguez (Tesis).pdf.jpgLaura Cristina Ramírez Rodríguez (Tesis).pdf.jpgGenerated Thumbnailimage/jpeg6327https://intellectum.unisabana.edu.co/bitstreams/8ba647a0-da92-4df1-845c-b9a7eda03abb/downloadc73c797098eb63062073dcee699726dbMD56false10818/30085oai:intellectum.unisabana.edu.co:10818/300852025-12-15 12:36:21.984http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internationalrestrictedhttps://intellectum.unisabana.edu.coIntellectum Repositorio Universidad de La Sabanacontactointellectum@unisabana.edu.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 |
