Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement

Biomaterials have become a fundamental tool in tissue engineering and regenerative medicine because of their capacity to mimic the original tissue. Currently, bone cements are being studied as bone substitute biomaterials in different pathologies, also compounds with materials such as hydroxyapatite...

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Autores:
Tipo de recurso:
Fecha de publicación:
2022
Institución:
Universidad Pedagógica y Tecnológica de Colombia
Repositorio:
RiUPTC: Repositorio Institucional UPTC
Idioma:
spa
OAI Identifier:
oai:repositorio.uptc.edu.co:001/15341
Acceso en línea:
https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018
https://repositorio.uptc.edu.co/handle/001/15341
Palabra clave:
Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad.
Hydroxyapatite, Biomaterial, Eggshell, Bioactivity.
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License
http://purl.org/coar/access_right/c_abf2
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oai_identifier_str oai:repositorio.uptc.edu.co:001/15341
network_acronym_str REPOUPTC2
network_name_str RiUPTC: Repositorio Institucional UPTC
repository_id_str
dc.title.en-US.fl_str_mv Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
dc.title.es-ES.fl_str_mv Bioactividad de hidroxiapatita obtenida a partir de cáscara de huevo para uso potencial como cemento óseo
title Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
spellingShingle Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad.
Hydroxyapatite, Biomaterial, Eggshell, Bioactivity.
title_short Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
title_full Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
title_fullStr Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
title_full_unstemmed Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
title_sort Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
dc.subject.es-ES.fl_str_mv Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad.
topic Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad.
Hydroxyapatite, Biomaterial, Eggshell, Bioactivity.
dc.subject.en-US.fl_str_mv Hydroxyapatite, Biomaterial, Eggshell, Bioactivity.
description Biomaterials have become a fundamental tool in tissue engineering and regenerative medicine because of their capacity to mimic the original tissue. Currently, bone cements are being studied as bone substitute biomaterials in different pathologies, also compounds with materials such as hydroxyapatite are analyzed to provide them bioactivity. In the present study, the main goal was to evaluate the bioactive nature of hydroxyapatite samples obtained from eggshells. Hydroxyapatite synthesis was performed by a wet chemical method, in which calcium oxide from eggshells and phosphoric acid were used as sources of calcium and phosphorus, respectively. The chemical characterization carried out by Raman spectroscopy and EDS showed that it was possible to obtain hydroxyapatite from this residue with a Ca/P ratio of 2,187. For the bioactivity study, the powder samples were immersed in simulated body fluid for 14 and 28 days.  Before and after the treatment the samples were characterized to determine their Ca/P ratio and behavior over time by Raman spectroscopy, and SEM-EDS microscopy. The characterization techniques allowed us to know that hydroxyapatite synthesized from eggshells had bioactive properties.  It is stable material in contact with the simulated body fluid, which suggests it is a great candidate to be used as an addition to conventional bone cement.
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2024-07-08T14:24:05Z
dc.date.available.none.fl_str_mv 2024-07-08T14:24:05Z
dc.date.none.fl_str_mv 2022-01-29
dc.type.none.fl_str_mv info:eu-repo/semantics/article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.none.fl_str_mv https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018
10.19053/01217488.v13.n1.2022.14018
dc.identifier.uri.none.fl_str_mv https://repositorio.uptc.edu.co/handle/001/15341
url https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018
https://repositorio.uptc.edu.co/handle/001/15341
identifier_str_mv 10.19053/01217488.v13.n1.2022.14018
dc.language.none.fl_str_mv spa
dc.language.iso.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018/12526
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.none.fl_str_mv application/pdf
dc.publisher.es-ES.fl_str_mv Universidad Pedagógica y Tecnológica de Colombia
dc.source.en-US.fl_str_mv Ciencia En Desarrollo; Vol. 13 No. 1 (2022): Vol. 13 Núm. 1 (2022): Vol 13, Núm.1 (2022): Enero-Junio; 103-114
dc.source.es-ES.fl_str_mv Ciencia en Desarrollo; Vol. 13 Núm. 1 (2022): Vol. 13 Núm. 1 (2022): Vol 13, Núm.1 (2022): Enero-Junio; 103-114
dc.source.none.fl_str_mv 2462-7658
0121-7488
institution Universidad Pedagógica y Tecnológica de Colombia
repository.name.fl_str_mv Repositorio Institucional UPTC
repository.mail.fl_str_mv repositorio.uptc@uptc.edu.co
_version_ 1839633867909103616
spelling 2022-01-292024-07-08T14:24:05Z2024-07-08T14:24:05Zhttps://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/1401810.19053/01217488.v13.n1.2022.14018https://repositorio.uptc.edu.co/handle/001/15341Biomaterials have become a fundamental tool in tissue engineering and regenerative medicine because of their capacity to mimic the original tissue. Currently, bone cements are being studied as bone substitute biomaterials in different pathologies, also compounds with materials such as hydroxyapatite are analyzed to provide them bioactivity. In the present study, the main goal was to evaluate the bioactive nature of hydroxyapatite samples obtained from eggshells. Hydroxyapatite synthesis was performed by a wet chemical method, in which calcium oxide from eggshells and phosphoric acid were used as sources of calcium and phosphorus, respectively. The chemical characterization carried out by Raman spectroscopy and EDS showed that it was possible to obtain hydroxyapatite from this residue with a Ca/P ratio of 2,187. For the bioactivity study, the powder samples were immersed in simulated body fluid for 14 and 28 days.  Before and after the treatment the samples were characterized to determine their Ca/P ratio and behavior over time by Raman spectroscopy, and SEM-EDS microscopy. The characterization techniques allowed us to know that hydroxyapatite synthesized from eggshells had bioactive properties.  It is stable material in contact with the simulated body fluid, which suggests it is a great candidate to be used as an addition to conventional bone cement.Los biomateriales se han constituido como una herramienta fundamental en la ingeniería de tejidos y la medicina regenerativa, debido a que tratan y en algunos casos logran mimetizar el tejido original. Actualmente se estudian los cementos óseos como biomateriales sustitutos de hueso en diferentes patologías, y se analizan diferentes compuestos con contenido de hidroxiapatita para dotarlos de bioactividad. En el presente estudio se tuvo como objetivo evaluar el carácter bioactivo en muestras de hidroxiapatita obtenida a partir de cáscara de huevo para usarse como posible adición a los cementos óseos. La síntesis de la hidroxiapatita se realizó por el método de precipitación, en la que se usó el óxido de calcio proveniente de las cáscaras de huevo y el ácido fosfórico como fuentes de calcio y fósforo, respectivamente. La caracterización química realizada por medio de espectroscopia Raman y EDS, permitió evidenciar que se logró obtener hidroxiapatita a partir de éste residuo con una relación Ca/P de 2,187. Para el estudio de bioactividad, se sumergieron las muestras en polvo en un fluido biológico simulado durante 14 y 28 días, y con espectroscopia Raman y microscopía SEM-EDS, se caracterizaron las muestras tanto antes como después del tratamiento para determinar su relación Ca/P y comportamiento con el tiempo. Las técnicas de caracterización permitieron determinar que la hidroxiapatita de cáscara de huevo presenta propiedades bioactivas y que además es un material estable al estar en contacto con el fluido biológico simulado, una gran candidata para usarse como adición a los cementos óseos convencionales.application/pdfspaspaUniversidad Pedagógica y Tecnológica de Colombiahttps://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018/12526Ciencia En Desarrollo; Vol. 13 No. 1 (2022): Vol. 13 Núm. 1 (2022): Vol 13, Núm.1 (2022): Enero-Junio; 103-114Ciencia en Desarrollo; Vol. 13 Núm. 1 (2022): Vol. 13 Núm. 1 (2022): Vol 13, Núm.1 (2022): Enero-Junio; 103-1142462-76580121-7488Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad.Hydroxyapatite, Biomaterial, Eggshell, Bioactivity.Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cementBioactividad de hidroxiapatita obtenida a partir de cáscara de huevo para uso potencial como cemento óseoinfo:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/access_right/c_abf2Gárcia-Sánchez, KarenQuiñones, Iber J.Gutierrez-M, Jose OscarCamargo-Amado, Rubén Basante-Romo, Mónica J.001/15341oai:repositorio.uptc.edu.co:001/153412025-07-18 10:56:40.326metadata.onlyhttps://repositorio.uptc.edu.coRepositorio Institucional UPTCrepositorio.uptc@uptc.edu.co