Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia

Autores:: López Muñoz, Luis Gilberto

Tipo de recurso:: Article of journal

Fecha de publicación:: 2026

Institución:: Universidad Pedagógica y Tecnológica de Colombia

Repositorio:: RiUPTC: Repositorio Institucional UPTC

Idioma:: spa

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dc.title.es-ES.fl_str_mv	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia
title	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia
spellingShingle	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia Antimicrobiana bioactivos cosmético propóleo fisicoquímica resina inhibición Antimicrobial bioactives cosmetic propolis physicochemical resin inhibition
title_short	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia
title_full	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia
title_fullStr	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia
title_full_unstemmed	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia
title_sort	Caracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-Colombia
dc.creator.fl_str_mv	López Muñoz, Luis Gilberto
dc.contributor.author.spa.fl_str_mv	López Muñoz, Luis Gilberto
dc.subject.none.fl_str_mv	Antimicrobiana bioactivos cosmético propóleo fisicoquímica resina inhibición Antimicrobial bioactives cosmetic propolis physicochemical resin inhibition
topic	Antimicrobiana bioactivos cosmético propóleo fisicoquímica resina inhibición Antimicrobial bioactives cosmetic propolis physicochemical resin inhibition
publishDate	2026
dc.date.accessioned.none.fl_str_mv	2026-10-17 23:11:30
dc.date.available.none.fl_str_mv	2026-10-17 23:11:30
dc.date.issued.none.fl_str_mv	2026-10-17
dc.type.spa.fl_str_mv	Artículo de revista
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dc.type.local.eng.fl_str_mv	Journal article
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dc.language.iso.spa.fl_str_mv	spa
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dc.relation.references.spa.fl_str_mv	G. Nates, E. Palacios, y A. Parra, “Efecto del cambio del paisaje en la estructura de la comunidad de abejas sin aguijón (Hymenoptera: Apidae) en Meta, Colombia,” Rev. Biol. Trop., vol. 56, no. 3, pp. 1295–1308, 2008. [2] D. P. P. Mora, K. B. Santiago, B. J. Conti, E. de Oliveira, F. L. Conte, L. P. Oliveira, and J. M. Sforcin, "The chemical composition and events related to the cytotoxic effects of propolis on osteosarcoma cells: A comparative assessment of Colombian samples," Phytother. Res., vol. 33, no. 3, pp. 591–601, 2019. doi: 10.1002/ptr.6246. [3] G. Nates, Abejas Corbiculadas de Colombia: Hymenoptera: Apidae, Bogotá, Colombia: CO-BAC, 2006, p. 156. [4] G. Nates, Iniciativa Colombiana de Polinizadores - Abejas – ICPA, Bogotá, D. C.: Universidad Nacional de Colombia, Departamento de Biología, 2016, p. 364. [5] J. Medina, R. Ospina, and G. Nates, "Efectos de la variación altitudinal sobre la polinización en cultivos de gulupa (Passiflora edulis F. edulis)," Acta Biol. Colomb., vol. 17, no. 2, pp. 379–393, 2012. [6] P. A. Sepúlveda, A. H. Smith, y R. A. Hoyos, “Efecto del arreglo espacial del agroecosistema sobre la diversidad de abejas (Hymenoptera: Apoidea) en cultivos de papa (Solanum tuberosum) en Antioquia, Colombia,” Rev. Colomb. Entomol., vol. 43, no. 1, pp. 55–63, 2017. [7] V. Plaza, Y. M. Velasco, y M. C. Gallego, “Oferta polínica para abejas en sistemas cafeteros en el municipio de Popayán, Cauca,” BMEUV, vol. 17, no. 2, p. S15, 2017. [8] G. Nates and J. M. Rosso, “Diversidad de abejas sin aguijón (Hymenoptera:Meliponini) utilizadas en meliponicultura en Colombia,” Acta Biol. Colomb., vol. 18, no. 3, pp. 415–426, 2013. [9] C. Medina, L. M. Carvajal, and A. López, "Propolis from native Stingless Bees: ultrasound-assisted extraction," Vitae, vol. 29, no. 2, 2022. doi: 10.17533/udea.vitae.v29n2a347446. [10] M. C. Ospina Ladino, D. Barrios Arenas, J. D. Aguilar Ortiz, D. Quintero Salazar, y L. G. López Muñoz, “Extracto acuoso de hojas de Gliricidia sepium: Un insecticida biológico efectivo contra Sitophilus oryzae,” Rev. Fac. Agron., vol. 123, 2024, doi: 10.24215/16699513e145. [11] G. Jorquera B, A. Valenzuela, J. Mayorga Mejía, G. Núñez, M. Gómez, G. Montenegro, V. Quezada, J. Echeverría, A. Costa de Camargo, G. Lino von Poser, and R. Bridi, "Exudate and Propolis from Escallonia pulverulenta: Phytochemical Characterization and Antibacterial Activity," Plants (Basel), vol. 13, no. 14, p. 1971, 2024. doi: 10.3390/plants13141971. [12] D. M. Buitrago, S. J. Perdomo, F. A. Silva, W. Cely, and G. I. Lafaurie, "Physicochemical Characterization, Antioxidant, and Proliferative Activity of Colombian Propolis Extracts: A Comparative Study," Molecules, vol. 29, no. 7, p. 1643, 2024. doi: 10.3390/molecules29071643. [13] D. N. Baptista, S. de Souza, E. de Menezes Oliveira, and S. de Almeida, "Extraction Kinetics of Brazilian Green Propolis and Chemical Characterization of its Volatiles," Chem. Biodivers., vol. 2024, no. 8, p. e202400610, 2024. doi: 10.1002/cbdv.202400610. [14] R. A. Mountford, M. Robertson, M. Taylor, and A. Clavijo, "Characterisation of New Zealand Propolis from Different Regions Based on Its Volatile Organic Compounds," Molecules, vol. 29, no. 13, p. 3143, 2024. doi: 10.3390/molecules29133143. [15] J. M. Feizy, M. Soleimanifard, and F. Maestrelli, "Casein-based nanocarriers for encapsulation of propolis extract: Design, fabrication, and characterization," JSFA Rep., vol. 4, no. 6, pp. 258–268, 2024. doi: 10.1002/jsf2.205. [16] B. Quintanilla-Casas et al., “The Volatile Metabolome — Gas Chromatography–Mass Spectrometry Approaches in the Context of Food Fraud,” Curr. Opin. Food Sci., vol. 61, p. 101235, 2025, doi: 10.1016/j.cofs.2024.101235. [17] M. Silva, A. Torres, y W. Hoffmann, “Determinación de propiedades fisicoquímicas de propóleos provenientes de cinco especies de abejas sin aguijón de Norte de Santander-Colombia,” Bistua Rev. Fac. Cienc. Básicas, vol. 14, no. 1, p. 03, 2016, doi: 10.24054/01204211.v1.n1.2016.192. [18] N. Thiex, L. Novotny, y A. Crawford, “Determination of ash in animal feed: AOAC Official Method 942.05 revisited,” J. AOAC Int., 2012, doi: 10.5740/jaoacint.12-129. [19] A. Kunaedi, I. Indawati, N. Karlina, Z. Fadhillah, C. D. Cantika, and A. A. Khulfiah, "Study on the optimization of mulberry leaf extract by macerating ethanol and microwave assisted extraction method (mae) with natural deep eutectic solvents (nades)," J. Farmasi Sains Dan Praktis, vol. 9, no. 1, pp. 11–19, 2023. doi: 10.31603/pharmacy.v9i1.7915. [20] D. Evitasari and E. Susanti, "Total Polyphenol Content in Green Tea (Camellia Sinensis) Using Maceration Extraction with Comparison of Ethanol – Water Solvent," Pharmademica J. Kefarmasian Dan Gizi, vol. 1, no. 1, pp. 16–23, 2021. doi: 10.54445/pharmademica.v1i1.5. [21] R. Pirow et al., “Mineral oil in food, cosmetic products, and in products regulated by other legislations,” Crit. Rev. Toxicol., 2019, doi: 10.1080/10408444.2019.1694862. [22] J. Gomes, J. Barbosa, and P. Teixeira, "The Inhibitory Concentration of Natural Food Preservatives May Be Biased by the Determination Methods," Foods, vol. 10, no. 5, p. 1009, 2021. doi: 10.3390/FOODS10051009. [23] D. Yin et al., “A modified Kirby-Bauer disc diffusion (mKB) method for accurately testing tigecycline susceptibility: a nation-wide multicenter comparative study,” J. Med. Microbiol., vol. 72, no. 8, 2023, doi: 10.1099/jmm.0.001671. [24] R. M. Zohdi et al., “Comparative study of different Malaysian Stingless bee propolis: Physicochemical characterization, Phytochemical contents and Antibacterial activity,” Res. J. Pharm. Technol., vol. 17, no. 3, pp. 1021–1028, 2024, doi: 10.52711/0974-360X.2024.00158. [25] E. Rendueles et al., “Biochemical Profile and Antioxidant Properties of Propolis from Northern Spain,” Foods, vol. 12, no. 23, 2023, doi: 10.3390/foods12234337. [26] J. Capellades, A. Junza, S. Samino, J. S. Brunner, G. Schabbauer, M. Vinaixa, and O. Yanes, "Exploring the use of gas chromatography coupled to chemical ionization mass spectrometry (GC-CI-MS) for stable isotope labeling in metabolomics," Anal. Chem., vol. 93, no. 3, pp. 1242–1248, 2021. doi: 10.1021/acs.analchem.0c02998. [27] V. A. Isidorov, J. Maslowiecka, L. Szoka, N. Pellizzer, D. Miranda, E. Olchowik, M. Zambrzycka, and I. Swiecicka, "Chemical Composition and Biological Activity of Argentinian Propolis of Four Species of Stingless Bees," Molecules, vol. 27, no. 22, p. 7686, 2022. doi: 10.3390/molecules27227686. [28] M. S. Oliveira et al., “Chemical Composition of Volatile Compounds in Apis mellifera Propolis from the Northeast Region of Pará State, Brazil,” Molecules, vol. 26, no. 11, p. 3462, 2021, doi: 10.3390/molecules26113462. [29] E. Souza et al., “Molecular network-guided chemical profile and mass spectrometry, volatile compounds, and antimicrobial activity of Scaptotrigona depilis propolis,” Rapid Commun. Mass Spectrom., vol. 36, no. 19, p. e9348, 2022, doi: 10.1002/rcm.9348. [30] A. Barbarić et al., “Characterization and Differentiation of Beech and Chestnut Honeydew Honeys: A Comparative Study,” Food Chem., vol. 477, p. 143446, 2025, doi: 10.1016/j.foodchem.2025.143446. [31] A. Çali y C. Çelik, “Determination of in Vitro Synergy and Antibiofilm Activities of Antimicrobials and Essential Oil Components,” Biofouling, vol. 40, no. 8, pp. 483–498, 2024, doi: 10.1080/08927014.2024.2381587. [32] X.-L. Hu, Z. Xu, M.-L. Liu, L.-S. Feng, y G.-D. Zhang, “Recent Developments of Coumarin Hybrids as Anti-Fungal Agents,” Curr. Top. Med. Chem., vol. 17, no. 29, pp. 3219–3231, 2017, doi: 10.2174/1568026618666171215100326. [33] G. B. Abza, J. H. Ahmed, G. Paulos, and K. N. Seshathri, "In vitro Analysis of the Antimicrobial Properties of Propolis Collected from Jimma, Ethiopia," J. Nat. Remedies, vol. 22, no. 2, p. 233, 2022. doi: 10.18311/jnr/2022/26587. [34] P. A. Gómez, L. Y. Jon, D. M. Torres, R. E. Amaranto, I. E. Díaz, and C. A. Medina, "Antibacterial, antibiofilm, and cytotoxic activities and chemical compositions of Peruvian propolis in an in vitro oral biofilm," F1000Research, vol. 10, p. 1093, 2021. doi: 10.12688/F1000RESEARCH.73602.1. [35] M. A. Özüsağlam, S. Tacer, S. Boulechfar, y A. Zellagui, “An Investigation of the Bactericidal and Fungicidal Effects of Algerian Propolis Extracts and Essential Oils,” Cumhuriyet Sci. J., vol. 43, no. 1, pp. 14–19, 2022, doi: 10.17776/csj.936040. [36] M. Yilmaz, Y. S. Gültekin, y P. Gültekin, “Evaluation of Honey Bees within the Scope of Sustainable Development Goals and Ecosystem Services,” Düzce Univ. J. Sci. Technol., vol. 11, no. 5, pp. 2397–2408, 2023, doi: 10.29130/dubited.1383016. [37] T. Karuncharoenpanich et al., “In Vitro Assessment of Antimicrobial Activity and Synergistic Effects of Ethanolic Extracts from Six Medicinal Plants,” J. Curr. Sci. Technol., vol. 15, no. 1, p. 85, 2024, doi: 10.59796/jcst. V15N1.2025.85.
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spelling	López Muñoz, Luis Gilberto2026-10-17 23:11:302026-10-17 23:11:302026-10-170121-748810.19053/uptc.01217488.v17.n1.2026.198452462-7658https://doi.org/10.19053/uptc.01217488.v17.n1.2026.19845application/pdfspaUniversidad Pedagógica y Tecnológica de Colombiahttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.esinfo:eu-repo/semantics/openAccessEsta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.http://purl.org/coar/access_right/c_abf2https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/19845Antimicrobianabioactivoscosmético propóleofisicoquímicaresinainhibiciónAntimicrobialbioactivescosmeticpropolisphysicochemicalresininhibitionCaracterización fisicoquímica, composición química y actividad antimicrobiana de diferentes propóleos en la vereda San Juan, Meta-ColombiaArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleJournal articleinfo:eu-repo/semantics/publishedVersionTexthttp://purl.org/coar/version/c_970fb48d4fbd8a85G. Nates, E. Palacios, y A. Parra, “Efecto del cambio del paisaje en la estructura de la comunidad de abejas sin aguijón (Hymenoptera: Apidae) en Meta, Colombia,” Rev. Biol. Trop., vol. 56, no. 3, pp. 1295–1308, 2008. [2] D. P. P. Mora, K. B. Santiago, B. J. Conti, E. de Oliveira, F. L. Conte, L. P. Oliveira, and J. M. Sforcin, "The chemical composition and events related to the cytotoxic effects of propolis on osteosarcoma cells: A comparative assessment of Colombian samples," Phytother. Res., vol. 33, no. 3, pp. 591–601, 2019. doi: 10.1002/ptr.6246. [3] G. Nates, Abejas Corbiculadas de Colombia: Hymenoptera: Apidae, Bogotá, Colombia: CO-BAC, 2006, p. 156. [4] G. Nates, Iniciativa Colombiana de Polinizadores - Abejas – ICPA, Bogotá, D. C.: Universidad Nacional de Colombia, Departamento de Biología, 2016, p. 364. [5] J. Medina, R. Ospina, and G. Nates, "Efectos de la variación altitudinal sobre la polinización en cultivos de gulupa (Passiflora edulis F. edulis)," Acta Biol. Colomb., vol. 17, no. 2, pp. 379–393, 2012. [6] P. A. Sepúlveda, A. H. Smith, y R. A. Hoyos, “Efecto del arreglo espacial del agroecosistema sobre la diversidad de abejas (Hymenoptera: Apoidea) en cultivos de papa (Solanum tuberosum) en Antioquia, Colombia,” Rev. Colomb. Entomol., vol. 43, no. 1, pp. 55–63, 2017. [7] V. Plaza, Y. M. Velasco, y M. C. Gallego, “Oferta polínica para abejas en sistemas cafeteros en el municipio de Popayán, Cauca,” BMEUV, vol. 17, no. 2, p. S15, 2017. [8] G. Nates and J. M. Rosso, “Diversidad de abejas sin aguijón (Hymenoptera:Meliponini) utilizadas en meliponicultura en Colombia,” Acta Biol. Colomb., vol. 18, no. 3, pp. 415–426, 2013. [9] C. Medina, L. M. Carvajal, and A. López, "Propolis from native Stingless Bees: ultrasound-assisted extraction," Vitae, vol. 29, no. 2, 2022. doi: 10.17533/udea.vitae.v29n2a347446. [10] M. C. Ospina Ladino, D. Barrios Arenas, J. D. Aguilar Ortiz, D. Quintero Salazar, y L. G. López Muñoz, “Extracto acuoso de hojas de Gliricidia sepium: Un insecticida biológico efectivo contra Sitophilus oryzae,” Rev. Fac. Agron., vol. 123, 2024, doi: 10.24215/16699513e145. [11] G. Jorquera B, A. Valenzuela, J. Mayorga Mejía, G. Núñez, M. Gómez, G. Montenegro, V. Quezada, J. Echeverría, A. Costa de Camargo, G. Lino von Poser, and R. Bridi, "Exudate and Propolis from Escallonia pulverulenta: Phytochemical Characterization and Antibacterial Activity," Plants (Basel), vol. 13, no. 14, p. 1971, 2024. doi: 10.3390/plants13141971. [12] D. M. Buitrago, S. J. Perdomo, F. A. Silva, W. Cely, and G. I. Lafaurie, "Physicochemical Characterization, Antioxidant, and Proliferative Activity of Colombian Propolis Extracts: A Comparative Study," Molecules, vol. 29, no. 7, p. 1643, 2024. doi: 10.3390/molecules29071643. [13] D. N. Baptista, S. de Souza, E. de Menezes Oliveira, and S. de Almeida, "Extraction Kinetics of Brazilian Green Propolis and Chemical Characterization of its Volatiles," Chem. Biodivers., vol. 2024, no. 8, p. e202400610, 2024. doi: 10.1002/cbdv.202400610. [14] R. A. Mountford, M. Robertson, M. Taylor, and A. Clavijo, "Characterisation of New Zealand Propolis from Different Regions Based on Its Volatile Organic Compounds," Molecules, vol. 29, no. 13, p. 3143, 2024. doi: 10.3390/molecules29133143. [15] J. M. Feizy, M. Soleimanifard, and F. Maestrelli, "Casein-based nanocarriers for encapsulation of propolis extract: Design, fabrication, and characterization," JSFA Rep., vol. 4, no. 6, pp. 258–268, 2024. doi: 10.1002/jsf2.205. [16] B. Quintanilla-Casas et al., “The Volatile Metabolome — Gas Chromatography–Mass Spectrometry Approaches in the Context of Food Fraud,” Curr. Opin. Food Sci., vol. 61, p. 101235, 2025, doi: 10.1016/j.cofs.2024.101235. [17] M. Silva, A. Torres, y W. Hoffmann, “Determinación de propiedades fisicoquímicas de propóleos provenientes de cinco especies de abejas sin aguijón de Norte de Santander-Colombia,” Bistua Rev. Fac. Cienc. Básicas, vol. 14, no. 1, p. 03, 2016, doi: 10.24054/01204211.v1.n1.2016.192. [18] N. Thiex, L. Novotny, y A. Crawford, “Determination of ash in animal feed: AOAC Official Method 942.05 revisited,” J. AOAC Int., 2012, doi: 10.5740/jaoacint.12-129. [19] A. Kunaedi, I. Indawati, N. Karlina, Z. Fadhillah, C. D. Cantika, and A. A. Khulfiah, "Study on the optimization of mulberry leaf extract by macerating ethanol and microwave assisted extraction method (mae) with natural deep eutectic solvents (nades)," J. Farmasi Sains Dan Praktis, vol. 9, no. 1, pp. 11–19, 2023. doi: 10.31603/pharmacy.v9i1.7915. [20] D. Evitasari and E. Susanti, "Total Polyphenol Content in Green Tea (Camellia Sinensis) Using Maceration Extraction with Comparison of Ethanol – Water Solvent," Pharmademica J. Kefarmasian Dan Gizi, vol. 1, no. 1, pp. 16–23, 2021. doi: 10.54445/pharmademica.v1i1.5. [21] R. Pirow et al., “Mineral oil in food, cosmetic products, and in products regulated by other legislations,” Crit. Rev. Toxicol., 2019, doi: 10.1080/10408444.2019.1694862. [22] J. Gomes, J. Barbosa, and P. Teixeira, "The Inhibitory Concentration of Natural Food Preservatives May Be Biased by the Determination Methods," Foods, vol. 10, no. 5, p. 1009, 2021. doi: 10.3390/FOODS10051009. [23] D. Yin et al., “A modified Kirby-Bauer disc diffusion (mKB) method for accurately testing tigecycline susceptibility: a nation-wide multicenter comparative study,” J. Med. Microbiol., vol. 72, no. 8, 2023, doi: 10.1099/jmm.0.001671. [24] R. M. Zohdi et al., “Comparative study of different Malaysian Stingless bee propolis: Physicochemical characterization, Phytochemical contents and Antibacterial activity,” Res. J. Pharm. Technol., vol. 17, no. 3, pp. 1021–1028, 2024, doi: 10.52711/0974-360X.2024.00158. [25] E. Rendueles et al., “Biochemical Profile and Antioxidant Properties of Propolis from Northern Spain,” Foods, vol. 12, no. 23, 2023, doi: 10.3390/foods12234337. [26] J. Capellades, A. Junza, S. Samino, J. S. Brunner, G. Schabbauer, M. Vinaixa, and O. Yanes, "Exploring the use of gas chromatography coupled to chemical ionization mass spectrometry (GC-CI-MS) for stable isotope labeling in metabolomics," Anal. Chem., vol. 93, no. 3, pp. 1242–1248, 2021. doi: 10.1021/acs.analchem.0c02998. [27] V. A. Isidorov, J. Maslowiecka, L. Szoka, N. Pellizzer, D. Miranda, E. Olchowik, M. Zambrzycka, and I. Swiecicka, "Chemical Composition and Biological Activity of Argentinian Propolis of Four Species of Stingless Bees," Molecules, vol. 27, no. 22, p. 7686, 2022. doi: 10.3390/molecules27227686. [28] M. S. Oliveira et al., “Chemical Composition of Volatile Compounds in Apis mellifera Propolis from the Northeast Region of Pará State, Brazil,” Molecules, vol. 26, no. 11, p. 3462, 2021, doi: 10.3390/molecules26113462. [29] E. Souza et al., “Molecular network-guided chemical profile and mass spectrometry, volatile compounds, and antimicrobial activity of Scaptotrigona depilis propolis,” Rapid Commun. Mass Spectrom., vol. 36, no. 19, p. e9348, 2022, doi: 10.1002/rcm.9348. [30] A. Barbarić et al., “Characterization and Differentiation of Beech and Chestnut Honeydew Honeys: A Comparative Study,” Food Chem., vol. 477, p. 143446, 2025, doi: 10.1016/j.foodchem.2025.143446. [31] A. Çali y C. Çelik, “Determination of in Vitro Synergy and Antibiofilm Activities of Antimicrobials and Essential Oil Components,” Biofouling, vol. 40, no. 8, pp. 483–498, 2024, doi: 10.1080/08927014.2024.2381587. [32] X.-L. Hu, Z. Xu, M.-L. Liu, L.-S. Feng, y G.-D. Zhang, “Recent Developments of Coumarin Hybrids as Anti-Fungal Agents,” Curr. Top. Med. Chem., vol. 17, no. 29, pp. 3219–3231, 2017, doi: 10.2174/1568026618666171215100326. [33] G. B. Abza, J. H. Ahmed, G. Paulos, and K. N. Seshathri, "In vitro Analysis of the Antimicrobial Properties of Propolis Collected from Jimma, Ethiopia," J. Nat. Remedies, vol. 22, no. 2, p. 233, 2022. doi: 10.18311/jnr/2022/26587. [34] P. A. Gómez, L. Y. Jon, D. M. Torres, R. E. Amaranto, I. E. Díaz, and C. A. Medina, "Antibacterial, antibiofilm, and cytotoxic activities and chemical compositions of Peruvian propolis in an in vitro oral biofilm," F1000Research, vol. 10, p. 1093, 2021. doi: 10.12688/F1000RESEARCH.73602.1. [35] M. A. Özüsağlam, S. Tacer, S. Boulechfar, y A. Zellagui, “An Investigation of the Bactericidal and Fungicidal Effects of Algerian Propolis Extracts and Essential Oils,” Cumhuriyet Sci. J., vol. 43, no. 1, pp. 14–19, 2022, doi: 10.17776/csj.936040. [36] M. Yilmaz, Y. S. Gültekin, y P. Gültekin, “Evaluation of Honey Bees within the Scope of Sustainable Development Goals and Ecosystem Services,” Düzce Univ. J. Sci. Technol., vol. 11, no. 5, pp. 2397–2408, 2023, doi: 10.29130/dubited.1383016. [37] T. Karuncharoenpanich et al., “In Vitro Assessment of Antimicrobial Activity and Synergistic Effects of Ethanolic Extracts from Six Medicinal Plants,” J. Curr. Sci. Technol., vol. 15, no. 1, p. 85, 2024, doi: 10.59796/jcst. V15N1.2025.85.209120317Ciencia en Desarrollohttps://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/download/19845/17475Núm. 1 , Año 2026 : Vol. 17 Núm. 1 (2026): Vol. 17 Núm. 1 (2026): Vol. 17 Núm. 1 (2026): Vol 17, Núm.1 (2026): Enero - JunioPublicationOREORE.xmltext/xml3037https://repositorio.uptc.edu.co/bitstreams/5bb7fea9-5170-424d-9cea-e56d183148d9/downloadae19dd7488121324c86b009da92ce5b2MD51falseAnonymousREAD001/21884oai:repositorio.uptc.edu.co:001/218842026-10-30 07:03:53.62https://creativecommons.org/licenses/by-nc-nd/4.0/deed.esmetadata.onlyhttps://repositorio.uptc.edu.coRepositorio Institucional UPTCbdigital@metabiblioteca.com

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