Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura

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Fecha de publicación:: 2026

Institución:: Universidad de Caldas

Repositorio:: Repositorio Institucional U. Caldas

Idioma:: spa

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network_name_str	Repositorio Institucional U. Caldas
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dc.title.none.fl_str_mv	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura
title	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura
spellingShingle	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura 610 - Medicina y salud::616 - Enfermedades 3. Ciencias Médicas y de la Salud::3B. Medicina Clínica::3B24. Psiquiatría Terapia electroconvulsiva Cognición Trastorno depresivo mayor Trastorno bipolar Psiquiatría Salud mental Tratamiento médico
title_short	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura
title_full	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura
title_fullStr	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura
title_full_unstemmed	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura
title_sort	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura
dc.contributor.none.fl_str_mv	Castaño Ramirez, Oscar Mauricio Valderrama Sánchez, Lenis Alexandra Villalba Garzón, Javier Andrés
dc.subject.none.fl_str_mv	610 - Medicina y salud::616 - Enfermedades 3. Ciencias Médicas y de la Salud::3B. Medicina Clínica::3B24. Psiquiatría Terapia electroconvulsiva Cognición Trastorno depresivo mayor Trastorno bipolar Psiquiatría Salud mental Tratamiento médico
topic	610 - Medicina y salud::616 - Enfermedades 3. Ciencias Médicas y de la Salud::3B. Medicina Clínica::3B24. Psiquiatría Terapia electroconvulsiva Cognición Trastorno depresivo mayor Trastorno bipolar Psiquiatría Salud mental Tratamiento médico
description	Tablas, ilustraciones
publishDate	2026
dc.date.none.fl_str_mv	2026-05-22T13:43:51Z 2026-05-22T13:43:51Z 2026-05-20 2028-05-19
dc.type.none.fl_str_mv	Trabajo de grado - Especialización http://purl.org/coar/resource_type/c_18ws Text info:eu-repo/semantics/report
dc.type.coar.fl_str_mv	http://purl.org/coar/resource_type/c_93fc
dc.identifier.none.fl_str_mv	https://repositorio.ucaldas.edu.co/handle/ucaldas/27014 Universidad de Caldas Repositorio Institucional Universidad de Caldas repositorio.ucaldas.edu.co
url	https://repositorio.ucaldas.edu.co/handle/ucaldas/27014
identifier_str_mv	Universidad de Caldas Repositorio Institucional Universidad de Caldas repositorio.ucaldas.edu.co
dc.language.none.fl_str_mv	spa
language	spa
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A novel strategy for continuation ECT in geriatric depression: Phase 2 of the PRIDE study. American Journal of Psychiatry. 2016 Nov 1;173(11):1110–8. doi:10.1176/appi.ajp.2016.16010118 PubMed PMID: 27418381. Nordenskjold A, Von Knorring L, Ljung T, Carlborg A, Brus O, Engstrom I. Continuation electroconvulsive therapy with pharmacotherapy versus pharmacotherapy alone for prevention of relapse of depression: A randomized controlled trial. Journal of ECT. 2013 Jun;29(2):86–92. doi:10.1097/YCT.0b013e318276591f PubMed PMID: 23303421. Smith GE, Rasmussen KG, Cullum CM, Felmlee-Devine MD, Petrides G, Rummans TA, et al. A randomized controlled trial comparing the memory effects of continuation electroconvulsive therapy versus continuation pharmacotherapy: Results from the Consortium for Research in ECT (CORE) study. Journal of Clinical Psychiatry. 2010 Feb;71(2):185–93. doi:10.4088/JCP.08m04797gre PubMed PMID: 20193646. 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dc.publisher.none.fl_str_mv	Universidad de Caldas Facultad de Ciencias para la Salud Manizales, Caldas Especialización en Psiquiatría
publisher.none.fl_str_mv	Universidad de Caldas Facultad de Ciencias para la Salud Manizales, Caldas Especialización en Psiquiatría
institution	Universidad de Caldas
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spelling	Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura610 - Medicina y salud::616 - Enfermedades3. Ciencias Médicas y de la Salud::3B. Medicina Clínica::3B24. PsiquiatríaTerapia electroconvulsivaCogniciónTrastorno depresivo mayorTrastorno bipolarPsiquiatríaSalud mentalTratamiento médicoTablas, ilustracionesObjetivo: sintetizar y analizar la evidencia sobre el impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno depresivo mayor y trastorno bipolar. Metodología: revisión sistemática realizada según la guía PRISMA 2020. Se incluyeron ensayos clínicos aleatorizados y estudios observacionales que evaluaran la cognición mediante instrumentos neuropsicológicos validados. La búsqueda se realizó en múltiples bases de datos hasta julio de 2025. Los resultados se sintetizaron de forma narrativa. Resultados: se incluyeron 8 estudios con diferentes diseños metodológicos. En ensayos clínicos y estudios longitudinales no se evidenció deterioro cognitivo global, observándose estabilidad en medidas como el MMSE y el MoCA, incluso tras exposiciones prolongadas. Algunos estudios reportaron mejorías en dominios específicos. Un estudio transversal identificó déficits en funciones ejecutivas y memoria de trabajo, no reproducidos en estudios longitudinales. Conclusiones: la terapia electroconvulsiva de mantenimiento presenta un perfil de seguridad neurocognitiva favorable. La individualización de los protocolos, el uso de parámetros técnicos modernos y el monitoreo cognitivo seriado son claves para optimizar su seguridad y aplicación clínica.Objective: to synthesize and analyze the available evidence on the cognitive impact of continuation and maintenance electroconvulsive therapy in patients with major depressive disorder and bipolar disorder. Methods: systematic review conducted according to PRISMA 2020 guidelines. Randomized controlled trials and observational studies assessing cognition with validated neuropsychological instruments were included. The search was performed across multiple databases up to July 2025. Results were synthesized narratively. Results: eight studies with different methodological designs were included. Randomized trials and longitudinal studies showed no evidence of global cognitive deterioration, with stability observed in measures such as MMSE and MoCA, even after prolonged exposure. Some studies reported improvements in specific domains. A cross-sectional study identified deficits in executive functions and working memory, which were not replicated in longitudinal designs. Conclusions: maintenance electroconvulsive therapy demonstrates a favorable neurocognitive safety profile. Individualized protocols, the use of modern technical parameters, and serial cognitive monitoring are key to optimizing its safety and clinical application.Lista de tablas -- Resumen -- Introducción -- Planteamiento del problema -- Pregunta de investigación -- Justificación -- Marco teórico -- Trastorno depresivo mayor -- Trastorno bipolar -- Terapia electroconvulsiva con anestesia y relajación -- Terapia electroconvulsiva de continuación (TECc) -- Terapia electroconvulsiva de mantenimiento (TECm) -- Aspectos técnicos relevantes -- Mecanismo de acción -- Efectos adversos -- Dominios cognitivos -- Atención y concentración -- Memoria -- Funciones ejecutivas -- Estado del arte -- Objetivos -- Objetivo general -- Objetivos específicos -- Metodología -- Tipo de estudio -- Hipótesis de investigación -- Protocolo para la elaboración del estudio -- Registro del protocolo -- Criterios de inclusión -- Criterios de exclusión -- Fuentes de información -- Estrategia de búsqueda -- Proceso de selección de los estudios -- Proceso de extracción de los datos -- Ítems de datos -- Evaluación del riesgo de sesgos de los estudios incluidos -- Medidas de efecto -- Sesgo de publicación -- Resultados -- Selección de los estudios -- Características de los estudios -- Riesgo de sesgos -- Síntesis de los resultados cognitivos -- Integración de la evidencia y consideraciones metodológicas -- Discusión -- Limitaciones del estudio -- Futuras líneas de investigación -- Conclusiones -- BibliografíaEspecializaciónSe realizó una revisión sistemática de la literatura, orientada a identificar, evaluar y sintetizar de manera estructurada la evidencia científica disponible sobre el impacto de la terapia electroconvulsiva de continuación y mantenimiento en el funcionamiento cognitivo de pacientes con trastorno depresivo mayor y trastorno bipolar.Especialista en PsiquiatríaUniversidad de CaldasFacultad de Ciencias para la SaludManizales, CaldasEspecialización en PsiquiatríaCastaño Ramirez, Oscar MauricioValderrama Sánchez, Lenis AlexandraVillalba Garzón, Javier AndrésJaramillo Jaramillo, Estefania2026-05-22T13:43:51Z2028-05-192026-05-22T13:43:51Z2026-05-20Trabajo de grado - Especializaciónhttp://purl.org/coar/resource_type/c_18wsTextinfo:eu-repo/semantics/reporthttp://purl.org/coar/resource_type/c_93fc72 páginasapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttps://repositorio.ucaldas.edu.co/handle/ucaldas/27014Universidad de CaldasRepositorio Institucional Universidad de Caldasrepositorio.ucaldas.edu.cospaGBD 2019 Mental Disorders Collaborators. 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Impacto cognitivo de la terapia electroconvulsiva de continuación y mantenimiento en pacientes con trastorno bipolar y trastorno depresivo mayor: una revisión sistemática de la literatura

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