Nuevos hallazgos en cuatro células subvaloradas del sistema inmune

El conocimiento sobre las células de la inmunidad innata ha tenido en los últimos años una transformación increíble; estas han pasado de ser simples efectores a verdaderos reguladores de la respuesta inmune. El neutrófilo tiene dentro de sus funciones actuales la presentación de antígeno, la probabl...

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2012
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Universidad de Caldas
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Repositorio Institucional U. Caldas
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spa
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https://repositorio.ucaldas.edu.co/handle/ucaldas/23790
https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/5850
Palabra clave:
Neutrófilos
eosinófilos
mastocitos
basófilos
inmunidad innata
avances recientes
neutrophils
eosinophils
mast cells
innate immunity
new findings
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openAccess
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Revista Biosalud - 2007
id REPOUCALDA_ba40804b2da7e2416ca759e271ac0b74
oai_identifier_str oai:repositorio.ucaldas.edu.co:ucaldas/23790
network_acronym_str REPOUCALDA
network_name_str Repositorio Institucional U. Caldas
repository_id_str
dc.title.none.fl_str_mv Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
New findings in four undervalued cells of the Immune system
title Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
spellingShingle Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
Neutrófilos
eosinófilos
mastocitos
basófilos
inmunidad innata
avances recientes
neutrophils
eosinophils
mast cells
innate immunity
new findings
title_short Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
title_full Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
title_fullStr Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
title_full_unstemmed Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
title_sort Nuevos hallazgos en cuatro células subvaloradas del sistema inmune
dc.subject.none.fl_str_mv Neutrófilos
eosinófilos
mastocitos
basófilos
inmunidad innata
avances recientes
neutrophils
eosinophils
mast cells
innate immunity
new findings
topic Neutrófilos
eosinófilos
mastocitos
basófilos
inmunidad innata
avances recientes
neutrophils
eosinophils
mast cells
innate immunity
new findings
description El conocimiento sobre las células de la inmunidad innata ha tenido en los últimos años una transformación increíble; estas han pasado de ser simples efectores a verdaderos reguladores de la respuesta inmune. El neutrófilo tiene dentro de sus funciones actuales la presentación de antígeno, la probable capacidad de estimular linfocitos T, la síntesis de diferentes citocinas con capacidad de alterar la respuesta inmune y la habilidad de regresar a la circulación luego de haber participado en el proceso inflamatorio tisular. La función de los eosinófilos en los fenómenos alérgicos está actualmente más clara que en épocas anteriores. Los eosinófilos igualmente poseen la capacidad de presentar antígenos y de estimular los linfocitos T; de igual manera, la generación de estos a partir de precursores de médula ósea está hoy en día mejor comprendida. Por su parte, los mastocitos y basófilos, células tan relacionadas anteriormente una con otra, tienen un proceso de formación más claro, sus funciones individuales están cada vez mejor documentadas, y abarcan desde la defensa contra enfermedades parasitarias, bacterianas, virales, hasta su papel en alergias. El estudio de estas células con una función aparentemente sencilla ha revolucionado enormemente el conocimiento acerca del sistema inmunológico.
publishDate 2012
dc.date.none.fl_str_mv 2012-07-21T00:00:00Z
2012-07-21T00:00:00Z
2012-07-21
2025-10-08T21:17:02Z
2025-10-08T21:17:02Z
dc.type.none.fl_str_mv Artículo de revista
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http://purl.org/coar/resource_type/c_dcae04bc
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https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/5850
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dc.relation.none.fl_str_mv 147
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Biosalud
Ashtekar A, Saha B. Poly’s plea: membership to the club of APCs. Trends Immunol 2003; 24:485-90.
Oehler L, Majdic O, Pickl W, Stöckl J, Riedl E, Drach J, et al. Neutrophil granulocyte–committed cells can be driven to acquire dendritic cell Characteristics. J. Exp. Med. 1998; 187:1019–28.
Ellis T, Beaman B. Interferon-γ activation of polymorphonuclear neutrophil function. Immunology 2004; 112:2-12.
Theilgaard K, Porse B, Borregaard N. Systems biology of neutrophil differentiation and immune response. Curr Opin Immunol 2006; 18:54-60.
Ludwig I, Geijtenbeek B, Van Kooyk I. Two way communication between neutrophils and dendritic cells. Curr Opin Pharmacol 2006; 6:408-13.
Urban C, Lourido S, Zychlinsky A. How do microbes evade neutrophil killing? Cell Microbiol 2006; 8:1696-97.
Fialkow L, Wang Y, Downey G. Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radic Biol Med. 2007; 42:153-64.
Winterbourn C, Hampton M, Livesey J, Kettle A. Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome. J Biol Chem 2006; 281:39860-869.
Buckley C, Ross E, McGettrick H, Osborne C, Haworth O, Schmutz C, et al. Identification of a phenotypically and functionally distinct population of long-lived neutrophils in a model of reverse endothelial migration. J Leukocyte Biol. 2006; 79:303-11.
Peng S. Neutrophil apoptosis in autoimmunity. J Mol Med. 2006; 84:122-25.
Ferrari D, La Sala A, Panther E, Norgauer J, Di Virgilio F, Idzko M. Activation of human eosinophils via P2 receptors: novel findings and future perspectives. J Leukocyte Biol. 2006; 79:7-15.
Mcnagny K, Graf T. Making eosinophils through subtle shifts in transcription factor expression. J. Exp. Med. 2002; 195:F43-F47.
Prussin C, Metcalfe D. IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol 2005; 117:S450-S456.
Shi H. Eosinophils function as antigen-presenting cells. J Leukocyte Biol. 2004; 76:520-27.
Bandeira C, Weller P. Mechanisms of eosinophil cytokine release. Mem. Inst. Oswaldo Cruz 2005; 100:73-81.
Kato M, Kita H, Tachibana A, Hayashi Y, Tsuchida Y, Kimura H. Dual signaling and effector pathways mediate human eosinophil activation by platelet-activating-factor. Intl Arch Allergy Immunol. 2004; 134:37-43.
Yamaguchi T, Suzuki M, Kimura H, Kato M. Role of protein kinase C in eosinophil function. Allergol Int. 2006; 55:245-52.
Wang J, Slungaard A. Role of eosinophil peroxidase in host defense and disease pathology. Arch Biochem Biophy 2006; 445:256-60.
Paoliello A, Oliveira S, Cunha F. Interleukin 4 induces the expression of inducible nitric oxide synthase in eosinophils. Cytokine 2005; 30:116-24.
Morgan D, Cherny V, Murphy R, Katz B, Decoursey T. The pH dependence of NADPH oxidase in uman eosinophils. J Physiol. 2005; 569:419-31.
Levy R. The role of cytosolic phospholipase A2-alfa in regulation of phagocytic functions. Biochim Biophys Acta 2006; 1761:1323-34.
Odemuyiwa S, Ghahary A, Li Y, Puttagunta L, Lee J, Musat S, et al. Cutting edge: human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase. J Immunol. 2004; 173:5909-13.
Adamko D, Odemuyiwa S, Vethanayagam D, Moqbel R. The rise of the phoenix: the expanding role of the eosinophil in health and disease. Allergy 2005; 60:13-22.
Puxeddu I, Ribatti D, Crivellato E, Levi F. Mast cells and eosinophils: a novel link between inflammation and angiogenesis in allergic diseases. J Allergy Clin Immunol. 2005; 116:531-36.
Shakoory B, Fitzgerald S, Lee S, Chi D, Krishnaswamy G. The role of human mast cell-derived cytokines in eosinophil biology. J Interferon Cytokine Res 2004; 24:271-81.
Kay A. The role of eosinophils in the pathogenesis of asthma. Trends Mol Med. 2005; 11:148-52.
Yu M, Tsai M, Tam S, Jones C, Zehnder J, Galli S. Mast cells can promote the development of multiple features of chronic asthma in mice. J. Clin. Invest. 2006; 116:1633-41.
Dawicki W, Marshall J. New and emerging roles for mast cells in host defence. Curr Opin Immunol. 2007; 19:31-38.
Okayama Y, Kawakami T. Development, migration, and survival of mast cells. Immunol Res. 2006; 34:97-115.
Kitamura Y, Ito A. Mast cell-committed progenitors. Proc. Natl. Acad. Sci. USA. 2005; 102:11129-130.
Gurish M, Boyce A. Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell. J Allergy Clin. Immunol. 2006; 117:1285-91.
Henz B, Maurer M, Lippert U, Worm M, Babina M. Mast cells as initiators of immunity and host defense. Exp Dermatol. 2001; 10:1-10.
Galli S, Nakae S, Tsai M. Mast cells in the development of adaptive immune responses. Nat Immunol. 2005; 6:135-42.
Féger F, Varadaradjalou S, Gao Z, Abraham S, Arock M. The role of mast cells in host defense and their subversion by bacterial pathogens. Trends Immunol. 2002; 23:151-58.
Theoharides T, Conti P. Mast cells: the JEKILL and HIDE of tumor growth. Trends Immunol. 2004; 25:235-41.
Barrett K. Mechanisms for amplified mediators release from colonic mast cells: implications for intestinal inflammatory diseases. World J Gastroenterol 2004; 10:617-19.
Kawakami T, Kitaura J. Mast cell survival and activatition by IgE in the absence of antigen: a consideration of the biologic mechanisms and relevance. J Immunol. 2005; 175:4167-73.
Yannay N, Razin E. Translation and transcription: the dual functionality of LysRS in mast cells. Mol Cells 2006; 22:127-32.
Li L, Yao Z. Mast cell and inhibitory receptors. Cell Mol Immunol. 2004; 1:408-15.
Poncet P, Arock M, David B. MHC class II-dependent activation of CD4+ T cell hybridomas by human mast cells through superantigen presentation. J Leukocyte Biol. 1999; 66:105-12.
Baram D, Peng Z, Medalia O, Mekori Y, Sagi R. Synaptotagmin II negatively regulates MHC class II presentation by mast cells. Mol Immunol. 2001; 38:1347-52.
Stelekati E, Orinska Z, Bulfone S. Mast cells in allergy: Innate instructors of adaptive responses. Immunobiol. 2007; 212:505-19.
Metz M, Maurer M. Mast cells―key effector cells in immune responses. Trends Immunol. 2007; 28:234-41.
Rodella L, Rezzani R, Buffoli B, Bonomini F, Tengattini S, Laffranchi L, et al. Role of mast cells in wound healing process after glass-fiber composite implant in rats. J. Cell. Mol. Med. 2006; 10:946-54.
Özdemir Ö. Immunosurveillance function of human mast cells? World J Gastroenterol 2005; 11:7054-56.
Ch’ng S, Wallis R, Yuan L, Davis P, Tan S. Mast cells and cutaneous malignancies. Mod. Pathol. 2006; 19:149-59.
Ito A, Oonuma J. Direct interaction between nerves and mast cells mediated by the SgIGSF/SynCAM adhesion molecule. J Pharmacol Sci. 2006; 102:1-5.
Triggiani M, Marone G. Basophil’s secrets revealed by flow cytometry. Allergy 2006; 61:1025-27.
Falcone F, Zillikens D, Gibbs B. The 21st century renaissance of the basophil? Current insights into its role in allergic responses and innate immunity. Exp Dermatol. 2006; 15:855-64.
Gibbs B. Human basophils as effectors and immunomodulators of allergic inflammation and innate immunity. Clin. Exp. Med. 2005; 5:43-49.
Arock M, Schneider E, Boissan M, Tricottet V, Dy M. Differentiation of human basophils: an overview of recent advances and pending questions. J Leukocyte Biol. 2002; 71:557-64.
Min B, Le Gros G, Paul W. Basophils: a potential liaison between innate and adaptive immunity. Allergol Int. 2006; 55:99-104.
Yoshimoto T, Nakanishi K. Roles of IL-18 in basophils and mast cells. Allergol Int. 2006; 55:105-13.
Dvorak A. Ultrastructural studies of human basophils and mast cells. J Histochem Cytochem 2005; 53:1043-70.
Falcone F, Pritchard D, Gibbs B. Do basophils play a role in immunity against parasites? Trends Parasitol. 2001; 17:126-29.
Shreffler W. Evaluation of basophil activation in food allergy: present and future applications. Curr. Opin Allergy Clin. Immunol. 2006; 6:226-33.
, Año 2007 : Enero - Diciembre
https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/download/5850/5289
dc.rights.none.fl_str_mv Revista Biosalud - 2007
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info:eu-repo/semantics/openAccess
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rights_invalid_str_mv Revista Biosalud - 2007
https://creativecommons.org/licenses/by-nc-sa/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad de Caldas
publisher.none.fl_str_mv Universidad de Caldas
dc.source.none.fl_str_mv https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/5850
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spelling Nuevos hallazgos en cuatro células subvaloradas del sistema inmuneNew findings in four undervalued cells of the Immune systemNeutrófiloseosinófilosmastocitosbasófilosinmunidad innataavances recientesneutrophilseosinophilsmast cellsinnate immunitynew findingsEl conocimiento sobre las células de la inmunidad innata ha tenido en los últimos años una transformación increíble; estas han pasado de ser simples efectores a verdaderos reguladores de la respuesta inmune. El neutrófilo tiene dentro de sus funciones actuales la presentación de antígeno, la probable capacidad de estimular linfocitos T, la síntesis de diferentes citocinas con capacidad de alterar la respuesta inmune y la habilidad de regresar a la circulación luego de haber participado en el proceso inflamatorio tisular. La función de los eosinófilos en los fenómenos alérgicos está actualmente más clara que en épocas anteriores. Los eosinófilos igualmente poseen la capacidad de presentar antígenos y de estimular los linfocitos T; de igual manera, la generación de estos a partir de precursores de médula ósea está hoy en día mejor comprendida. Por su parte, los mastocitos y basófilos, células tan relacionadas anteriormente una con otra, tienen un proceso de formación más claro, sus funciones individuales están cada vez mejor documentadas, y abarcan desde la defensa contra enfermedades parasitarias, bacterianas, virales, hasta su papel en alergias. El estudio de estas células con una función aparentemente sencilla ha revolucionado enormemente el conocimiento acerca del sistema inmunológico.The knowledge about cells associated with the innate immunity has had an incredible transformation in the last years; they have changed from simple effectors to true regulators of the immune response. Within their current functions, the neutrophils control antigen presentation, the probable lymphocyte stimulation ability, the synthesis of different cytokines with the capacity to alter the immune response, and the ability to return to circulation after participating in the tissue inflammatory process. The eosinophil function in the allergic phenomena is currently clearer than in past years. Likewise, the eosinophils have the antigen presentation and T lymphocyte stimulation ability, as well as the eosinophil generation from bone marrow precursors is nowadays better understood. On the other hand, mast cells and basophils, cells previously related one to the other, have a clearer formation process, their individual functions are everyday better documented, and include defense against parasitic, bacterial, viral diseases to their function in allergies. The study of these cells with apparently simple functions has greatly revolutionized the knowledge on the immune system.Universidad de Caldas2012-07-21T00:00:00Z2025-10-08T21:17:02Z2012-07-21T00:00:00Z2025-10-08T21:17:02Z2012-07-21Artículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_dcae04bcTextinfo:eu-repo/semantics/articleJournal articlehttp://purl.org/redcol/resource_type/ARTREVinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1application/pdf1657-9550https://repositorio.ucaldas.edu.co/handle/ucaldas/237902462-960Xhttps://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/5850https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/5850spa1471316BiosaludAshtekar A, Saha B. Poly’s plea: membership to the club of APCs. Trends Immunol 2003; 24:485-90.Oehler L, Majdic O, Pickl W, Stöckl J, Riedl E, Drach J, et al. Neutrophil granulocyte–committed cells can be driven to acquire dendritic cell Characteristics. J. Exp. Med. 1998; 187:1019–28.Ellis T, Beaman B. Interferon-γ activation of polymorphonuclear neutrophil function. Immunology 2004; 112:2-12.Theilgaard K, Porse B, Borregaard N. Systems biology of neutrophil differentiation and immune response. Curr Opin Immunol 2006; 18:54-60.Ludwig I, Geijtenbeek B, Van Kooyk I. Two way communication between neutrophils and dendritic cells. Curr Opin Pharmacol 2006; 6:408-13.Urban C, Lourido S, Zychlinsky A. How do microbes evade neutrophil killing? Cell Microbiol 2006; 8:1696-97.Fialkow L, Wang Y, Downey G. Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radic Biol Med. 2007; 42:153-64.Winterbourn C, Hampton M, Livesey J, Kettle A. Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome. J Biol Chem 2006; 281:39860-869.Buckley C, Ross E, McGettrick H, Osborne C, Haworth O, Schmutz C, et al. Identification of a phenotypically and functionally distinct population of long-lived neutrophils in a model of reverse endothelial migration. J Leukocyte Biol. 2006; 79:303-11.Peng S. Neutrophil apoptosis in autoimmunity. J Mol Med. 2006; 84:122-25.Ferrari D, La Sala A, Panther E, Norgauer J, Di Virgilio F, Idzko M. Activation of human eosinophils via P2 receptors: novel findings and future perspectives. J Leukocyte Biol. 2006; 79:7-15.Mcnagny K, Graf T. Making eosinophils through subtle shifts in transcription factor expression. J. Exp. Med. 2002; 195:F43-F47.Prussin C, Metcalfe D. IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol 2005; 117:S450-S456.Shi H. Eosinophils function as antigen-presenting cells. J Leukocyte Biol. 2004; 76:520-27.Bandeira C, Weller P. Mechanisms of eosinophil cytokine release. Mem. Inst. Oswaldo Cruz 2005; 100:73-81.Kato M, Kita H, Tachibana A, Hayashi Y, Tsuchida Y, Kimura H. Dual signaling and effector pathways mediate human eosinophil activation by platelet-activating-factor. Intl Arch Allergy Immunol. 2004; 134:37-43.Yamaguchi T, Suzuki M, Kimura H, Kato M. Role of protein kinase C in eosinophil function. Allergol Int. 2006; 55:245-52.Wang J, Slungaard A. Role of eosinophil peroxidase in host defense and disease pathology. Arch Biochem Biophy 2006; 445:256-60.Paoliello A, Oliveira S, Cunha F. Interleukin 4 induces the expression of inducible nitric oxide synthase in eosinophils. Cytokine 2005; 30:116-24.Morgan D, Cherny V, Murphy R, Katz B, Decoursey T. The pH dependence of NADPH oxidase in uman eosinophils. J Physiol. 2005; 569:419-31.Levy R. The role of cytosolic phospholipase A2-alfa in regulation of phagocytic functions. Biochim Biophys Acta 2006; 1761:1323-34.Odemuyiwa S, Ghahary A, Li Y, Puttagunta L, Lee J, Musat S, et al. Cutting edge: human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase. J Immunol. 2004; 173:5909-13.Adamko D, Odemuyiwa S, Vethanayagam D, Moqbel R. The rise of the phoenix: the expanding role of the eosinophil in health and disease. Allergy 2005; 60:13-22.Puxeddu I, Ribatti D, Crivellato E, Levi F. Mast cells and eosinophils: a novel link between inflammation and angiogenesis in allergic diseases. J Allergy Clin Immunol. 2005; 116:531-36.Shakoory B, Fitzgerald S, Lee S, Chi D, Krishnaswamy G. The role of human mast cell-derived cytokines in eosinophil biology. J Interferon Cytokine Res 2004; 24:271-81.Kay A. The role of eosinophils in the pathogenesis of asthma. Trends Mol Med. 2005; 11:148-52.Yu M, Tsai M, Tam S, Jones C, Zehnder J, Galli S. Mast cells can promote the development of multiple features of chronic asthma in mice. J. Clin. Invest. 2006; 116:1633-41.Dawicki W, Marshall J. New and emerging roles for mast cells in host defence. Curr Opin Immunol. 2007; 19:31-38.Okayama Y, Kawakami T. Development, migration, and survival of mast cells. Immunol Res. 2006; 34:97-115.Kitamura Y, Ito A. Mast cell-committed progenitors. Proc. Natl. Acad. Sci. USA. 2005; 102:11129-130.Gurish M, Boyce A. Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell. J Allergy Clin. Immunol. 2006; 117:1285-91.Henz B, Maurer M, Lippert U, Worm M, Babina M. Mast cells as initiators of immunity and host defense. Exp Dermatol. 2001; 10:1-10.Galli S, Nakae S, Tsai M. Mast cells in the development of adaptive immune responses. Nat Immunol. 2005; 6:135-42.Féger F, Varadaradjalou S, Gao Z, Abraham S, Arock M. The role of mast cells in host defense and their subversion by bacterial pathogens. Trends Immunol. 2002; 23:151-58.Theoharides T, Conti P. Mast cells: the JEKILL and HIDE of tumor growth. Trends Immunol. 2004; 25:235-41.Barrett K. Mechanisms for amplified mediators release from colonic mast cells: implications for intestinal inflammatory diseases. World J Gastroenterol 2004; 10:617-19.Kawakami T, Kitaura J. Mast cell survival and activatition by IgE in the absence of antigen: a consideration of the biologic mechanisms and relevance. J Immunol. 2005; 175:4167-73.Yannay N, Razin E. Translation and transcription: the dual functionality of LysRS in mast cells. Mol Cells 2006; 22:127-32.Li L, Yao Z. Mast cell and inhibitory receptors. Cell Mol Immunol. 2004; 1:408-15.Poncet P, Arock M, David B. MHC class II-dependent activation of CD4+ T cell hybridomas by human mast cells through superantigen presentation. J Leukocyte Biol. 1999; 66:105-12.Baram D, Peng Z, Medalia O, Mekori Y, Sagi R. Synaptotagmin II negatively regulates MHC class II presentation by mast cells. Mol Immunol. 2001; 38:1347-52.Stelekati E, Orinska Z, Bulfone S. Mast cells in allergy: Innate instructors of adaptive responses. Immunobiol. 2007; 212:505-19.Metz M, Maurer M. Mast cells―key effector cells in immune responses. Trends Immunol. 2007; 28:234-41.Rodella L, Rezzani R, Buffoli B, Bonomini F, Tengattini S, Laffranchi L, et al. Role of mast cells in wound healing process after glass-fiber composite implant in rats. J. Cell. Mol. Med. 2006; 10:946-54.Özdemir Ö. Immunosurveillance function of human mast cells? World J Gastroenterol 2005; 11:7054-56.Ch’ng S, Wallis R, Yuan L, Davis P, Tan S. Mast cells and cutaneous malignancies. Mod. Pathol. 2006; 19:149-59.Ito A, Oonuma J. Direct interaction between nerves and mast cells mediated by the SgIGSF/SynCAM adhesion molecule. J Pharmacol Sci. 2006; 102:1-5.Triggiani M, Marone G. Basophil’s secrets revealed by flow cytometry. Allergy 2006; 61:1025-27.Falcone F, Zillikens D, Gibbs B. The 21st century renaissance of the basophil? Current insights into its role in allergic responses and innate immunity. Exp Dermatol. 2006; 15:855-64.Gibbs B. Human basophils as effectors and immunomodulators of allergic inflammation and innate immunity. Clin. Exp. Med. 2005; 5:43-49.Arock M, Schneider E, Boissan M, Tricottet V, Dy M. Differentiation of human basophils: an overview of recent advances and pending questions. J Leukocyte Biol. 2002; 71:557-64.Min B, Le Gros G, Paul W. Basophils: a potential liaison between innate and adaptive immunity. Allergol Int. 2006; 55:99-104.Yoshimoto T, Nakanishi K. Roles of IL-18 in basophils and mast cells. Allergol Int. 2006; 55:105-13.Dvorak A. Ultrastructural studies of human basophils and mast cells. J Histochem Cytochem 2005; 53:1043-70.Falcone F, Pritchard D, Gibbs B. Do basophils play a role in immunity against parasites? Trends Parasitol. 2001; 17:126-29.Shreffler W. Evaluation of basophil activation in food allergy: present and future applications. Curr. Opin Allergy Clin. Immunol. 2006; 6:226-33., Año 2007 : Enero - Diciembrehttps://revistasojs.ucaldas.edu.co/index.php/biosalud/article/download/5850/5289Revista Biosalud - 2007https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2López Zapata, Diego Fernandooai:repositorio.ucaldas.edu.co:ucaldas/237902025-10-08T21:17:02Z