Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica

Introducción En condiciones normales, nuestro cerebro es capaz de actualizar sus representaciones almacenadas en fuerza o contenido por el proceso de reconsolidación. De esta forma, una memoria consolidada es reactivada y entra en un periodo transitorio de inestabilidad seguido por una fase de reest...

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Autores:
Fernández, Rodrigo S
Allegri, Ricardo
Tipo de recurso:
Article of journal
Fecha de publicación:
2019
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
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spa
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oai:repositorio.cuc.edu.co:11323/7454
Acceso en línea:
https://hdl.handle.net/11323/7454
https://doi.org/10.1016/j.neuarg.2019.06.002
https://repositorio.cuc.edu.co/
Palabra clave:
Memoria
Reconsolidación
Consolidación
Error de predicción
Traslacional
Neuropsiquiatría
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openAccess
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Attribution-NonCommercial-NoDerivatives 4.0 International
id RCUC2_8bbee975cee5debbeaef4292145e7b5f
oai_identifier_str oai:repositorio.cuc.edu.co:11323/7454
network_acronym_str RCUC2
network_name_str REDICUC - Repositorio CUC
repository_id_str
dc.title.spa.fl_str_mv Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
dc.title.translated.spa.fl_str_mv On the instability of memories and its transformation by the reconsolidation process: Contributions for its clinical consideration
title Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
spellingShingle Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
Memoria
Reconsolidación
Consolidación
Error de predicción
Traslacional
Neuropsiquiatría
title_short Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
title_full Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
title_fullStr Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
title_full_unstemmed Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
title_sort Acerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínica
dc.creator.fl_str_mv Fernández, Rodrigo S
Allegri, Ricardo
dc.contributor.author.spa.fl_str_mv Fernández, Rodrigo S
Allegri, Ricardo
dc.subject.spa.fl_str_mv Memoria
Reconsolidación
Consolidación
Error de predicción
Traslacional
Neuropsiquiatría
topic Memoria
Reconsolidación
Consolidación
Error de predicción
Traslacional
Neuropsiquiatría
description Introducción En condiciones normales, nuestro cerebro es capaz de actualizar sus representaciones almacenadas en fuerza o contenido por el proceso de reconsolidación. De esta forma, una memoria consolidada es reactivada y entra en un periodo transitorio de inestabilidad seguido por una fase de reestabilización para persistir. El inicio del proceso de reconsolidación depende de la detección de una incongruencia entre la predicción realizada y lo ocurrido (error de predicción), en el que la predicción inicial se ajusta acorde al error generado. Desarrollo La neurociencia, la psicología y otras ciencias básicas han aportado perspectivas novedosas en la investigación y abordaje de diversos trastornos psiquiátricos. En este sentido, establecieron una relación íntima entre la memoria y las enfermedades mentales. El paradigma de la reconsolidación de la memoria ha sido propuesto no solo como el mecanismo responsable del mantenimiento de algunas psicopatologías sino también como una oportunidad de establecer nuevos tratamientos. En la presente revisión se desarrollará el concepto de reconsolidación, ampliamente estudiado en animales y humanos en los últimos 20 años, y se destacarán sus potenciales aplicaciones traslacionales a la clínica neuropsiquiátrica. Conclusiones Existen evidencias de que el proceso de reconsolidación tendría utilidad terapéutica en la clínica neuropsiquiátrica. Sin embargo, aún se requieren estudios mayores y más complejos.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2020-11-24T16:24:48Z
dc.date.available.none.fl_str_mv 2020-11-24T16:24:48Z
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/article
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/ART
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
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dc.identifier.uri.spa.fl_str_mv https://hdl.handle.net/11323/7454
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.neuarg.2019.06.002
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
url https://hdl.handle.net/11323/7454
https://doi.org/10.1016/j.neuarg.2019.06.002
https://repositorio.cuc.edu.co/
identifier_str_mv Corporación Universidad de la Costa
REDICUC - Repositorio CUC
dc.language.iso.none.fl_str_mv spa
language spa
dc.relation.references.spa.fl_str_mv Bubic, A., Yves von Cramon, D., Schubotz, R.I. Prediction, cognition and the brain (2010) Frontiers in Human Neuroscience, 4, . Cited 321 times. DOI: 10.3389/fnhum.2010.00025
Buzsáki, G., Peyrache, A., Kubie, J. Emergence of cognition from action (2014) Cold Spring Harbor Symposia on Quantitative Biology, 79, pp. 41-50. Cited 33 times. DOI: 10.1101/sqb.2014.79.024679
Dudai, Y. (2002) Memory from A to Z. Keywords, Concepts and Beyond. Cited 133 times.
Squire, L.R., Genzel, L., Wixted, J.T., Morris, R.G. Memory consolidation (2015) Cold Spring Harbor Perspectives in Biology, 7 (8), 21 p. Cited 150 times. DOI: 10.1101/cshperspect.a021766
Kandel, E.R. The molecular biology of memory storage: A dialog between genes and synapses (2001) Bioscience Reports, 21 (5), pp. 565-611. Cited 239 times. DOI: 10.1023/A
McGaugh, J.L. Memory - A century of consolidation (2000) Science, 287 (5451), pp. 248-251. Cited 2890 times. DOI: 10.1126/science.287.5451.248
Abel, T., Lattal, K.M. Molecular mechanisms of memory acquisition, consolidation and retrieval (2001) Current Opinion in Neurobiology, 11 (2), pp. 180-187. Cited 500 times. DOI: 10.1016/S0959-4388(00)00194-X
Kitamura, T., Ogawa, S.K., Roy, D.S., Okuyama, T., Morrissey, M.D., Smith, L.M., Redondo, R.L., Tonegawa, S. Engrams and circuits crucial for systems consolidation of a memory (2017) Science, 356 (6333), pp. 73-78. Cited 256 times. DOI: 10.1126/science.aam6808
Gilboa, A., Marlatte, H. Neurobiology of Schemas and Schema-Mediated Memory (2017) Trends in Cognitive Sciences, 21 (8), pp. 618-631. Cited 129 times. DOI: 10.1016/j.tics.2017.04.013
Dudai, Y. Predicting not to predict too much: How the cellular machinery of memory anticipates the uncertain future (2009) Philosophical Transactions of the Royal Society B: Biological Sciences, 364 (1521), pp. 1255-1262. Cited 59 times. DOI: 10.1098/rstb.2008.0320
Niv, Y Reinforcement learning in the brain (2009) Journal of Mathematical Psychology, 53 (3), pp. 139-154. Cited 237 times. DOI: 10.1016/j.jmp.2008.12.005
Nader, K. Reconsolidation and the dynamic nature of memory (2015) Cold Spring Harbor Perspectives in Biology, 7 (10), art. no. a021782, 17 p. Cited 69 times. DOI: 10.1101/cshperspect.a021782
Den Ouden, H.E.M., Friston, K.J., Daw, N.D., McIntosh, A.R., Stephan, K.E. A dual role for prediction error in associative learning (2009) Cerebral Cortex, 19 (5), pp. 1175-1185. Cited 193 times. DOI: 10.1093/cercor/bhn161
Fernández, R.S., Pedreira, M.E., Boccia, M.M. Does reconsolidation occur in natural settings? Memory reconsolidation and anxiety disorders (2017) Clinical Psychology Review, 57, pp. 45-58. Cited 9 times. DOI: 10.1016/j.cpr.2017.08.004
Gershman, S.J., Monfils, M.-H., Norman, K.A., Niv, Y. The computational nature of memory modification (2017) eLife, 6, art. no. e23763, . Cited 41 times. DOI: 10.7554/eLife.23763
Bouton, M.E. Context, time, and memory retrieval in the interference paradigms of pavlovian learning (1993) Psychological Bulletin, 114 (1), pp. 80-99. Cited 1342 times. DOI: 10.1037/0033-2909.114.1.80
Gordon, W.C. Mechanisms of cue-induced retention enhancement (1981) Information Processing in Animals: Memory Mechanisms, pp. 319-339. Cited 78 times.
Fernández, R.S., Boccia, M.M., Pedreira, M.E. The fate of memory: Reconsolidation and the case of Prediction Error (2016) Neuroscience and Biobehavioral Reviews, 68, pp. 423-441. Cited 59 times. DOI: 10.1016/j.neubiorev.2016.06.004
Forcato, C., Fernandez, R.S., Pedreira, M.E. Strengthening a consolidated memory: The key role of the reconsolidation process (2014) Journal of Physiology Paris, 108 (4-6), pp. 323-333. Cited 38 times. DOI: 10.1016/j.jphysparis.2014.09.001
Dudai, Y. The restless engram: Consolidations never end (2012) Annual Review of Neuroscience, 35, pp. 227-247. Cited 329 times. DOI: 10.1146/annurev-neuro-062111-150500
Fernández, R.S., Bavassi, L., Kaczer, L., Forcato, C., Pedreira, M.E. Interference conditions of the reconsolidation process in humans: The role of valence and different memory systems (2016) Frontiers in Human Neuroscience, 10 (DEC2016), art. no. 641, . Cited 7 times. DOI: 10.3389/fnhum.2016.00641
Hassabis, D., Maguire, E.A. Deconstructing episodic memory with construction (2007) Trends in Cognitive Sciences, 11 (7), pp. 299-306. Cited 663 times. DOI: 10.1016/j.tics.2007.05.001
Lewis, D.J. Psychobiology of active and inactive memory (1979) Psychological Bulletin, 86 (5), pp. 1054-1083. Cited 354 times. DOI: 10.1037/0033-2909.86.5.1054
Misanin, J.R., Miller, R.R., Lewis, D.J. Retrograde amnesia produced by electroconvulsive shock after reactivation of a consolidated memory trace (1968) Science, 160 (3827), pp. 554-555. Cited 591 times. DOI: 10.1126/science.160.3827.554
Spear, N.E. Retrieval of memory in animals (1973) Psychological Review, 80 (3), pp. 163-194. Cited 384 times. DOI: 10.1037/h0034326
Przybyslawski, J., Sara, S.J. Reconsolidation of memory after its reactivation (1997) Behavioural Brain Research, 84 (1-2), pp. 241-246. Cited 355 times. DOI: 10.1016/S0166-4328(96)00153-2
Nader, K., Schafe, G.E., Le Doux, J.E. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval (2000) Nature, 406 (6797), pp. 722-726. Cited 1710 times. DOI: 10.1038/35021052
Alberini, C. Memory Reconsolidation (2013) Memory Reconsolidation, 320 p. Cited 13 times. DOI: 10.1016/C2010-0-67992-2
Boccia, M.M., Blake, M.G., Krawczyk, M.C., Baratti, C.M. Hippocampal alpha7 nicotinic receptors modulate memory reconsolidation of an inhibitory avoidance task in mice (2010) Neuroscience, 171 (2), pp. 531-543. Cited 37 times. DOI: 10.1016/j.neuroscience.2010.08.027
Krawczyk, M.C., Fernández, R.S., Pedreira, M.E., Boccia, M.M. Toward a better understanding on the role of prediction error on memory processes: From bench to clinic (2017) Neurobiology of Learning and Memory, 142, pp. 13-20. Cited 15 times. DOI: 10.1016/j.nlm.2016.12.011
Lee, J.L.C. Memory reconsolidation mediates the updating of hippocampal memory content (2010) Frontiers in Behavioral Neuroscience, 4 (NOV), art. no. 168, . Cited 116 times. DOI: 10.3389/fnbeh.2010.00168
Pedreira, M.E., Pérez-Cuesta, L.M., Maldonado, H. Mismatch between what is expected and what actually occurs triggers memory reconsolidation or extinction (2004) Learning and Memory, 11 (5), pp. 579-585. Cited 250 times. DOI: 10.1101/lm.76904
Schiller, D., Monfils, M.-H., Raio, C.M., Johnson, D.C., Ledoux, J.E., Phelps, E.A. Preventing the return of fear in humans using reconsolidation update mechanisms (2010) Nature, 463 (7277), pp. 49-53. Cited 752 times. DOI: 10.1038/nature08637
Alberini, C.M. Mechanisms of memory stabilization: Are consolidation and reconsolidation similar or distinct processes? (2005) Trends in Neurosciences, 28 (1), pp. 51-56. Cited 450 times. DOI: 10.1016/j.tins.2004.11.001
Finnie, P.S.B., Nader, K. The role of metaplasticity mechanisms in regulating memory destabilization and reconsolidation (2012) Neuroscience and Biobehavioral Reviews, 36 (7), pp. 1667-1707. Cited 116 times. DOI: 10.1016/j.neubiorev.2012.03.008
Flavell, C.R., Lambert, E.A., Winters, B.D., Bredy, T.W. Mechanisms governing the reactivation-dependent destabilization of memories and their role in extinction (2013) Frontiers in Behavioral Neuroscience, 7 (DEC), . Cited 28 times. DOI: 10.3389/fnbeh.2013.00214
Alberini, C.M., Ledoux, J.E. Memory reconsolidation (2013) Current Biology, 23 (17), pp. R746-R750. Cited 123 times. DOI: 10.1016/j.cub.2013.06.046
Tronson, N.C., Taylor, J.R. Molecular mechanisms of memory reconsolidation (2007) Nature Reviews Neuroscience, 8 (4), pp. 262-275. Cited 556 times. DOI: 10.1038/nrn2090
Exton-McGuinness, M.T.J., Patton, R.C., Sacco, L.B., Lee, J.L.C. Reconsolidation of a well-learned instrumental memory (2014) Learning and Memory, 21 (9), pp. 468-477. Cited 35 times. DOI: 10.1101/lm.035543.114
Pedreira, M.E., Maldonado, H. Protein synthesis subserves reconsolidation or extinction depending on reminder duration (2003) Neuron, 38 (6), pp. 863-869. Cited 321 times. DOI: 10.1016/S0896-6273(03)00352-0
Rescorla, R.A., Wagner, A.R. A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement (1972) Classical Conditioning II: Current Research and Theory, pp. 64-99. Cited 5698 times
De Oliveira Alvares, L., Crestani, A.P., Cassini, L.F., Haubrich, J., Santana, F., Quillfeldt, J.A. Reactivation enables memory updating, precision-keeping and strengthening: Exploring the possible biological roles of reconsolidation (2013) Neuroscience, 244, pp. 42-48. Cited 66 times. DOI: 10.1016/j.neuroscience.2013.04.005
Forcato, C., Argibay, P.F., Pedreira, M.E., Maldonado, H. Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure (2009) Neurobiology of Learning and Memory, 91 (1), pp. 50-57. Cited 109 times. DOI: 10.1016/j.nlm.2008.09.011
Kindt, M., Soeter, M., Vervliet, B. Beyond extinction: Erasing human fear responses and preventing the return of fear (2009) Nature Neuroscience, 12 (3), pp. 256-258. Cited 523 times. DOI: 10.1038/nn.2271
Alfei, J.M., Monti, R.I.F., Molina, V.A., Bueno, A.M., Urcelay, G.P. Prediction error and trace dominance determine the fate of fear memories after post-training manipulations (2015) Learning and Memory, 22 (8), pp. 385-400. Cited 38 times. DOI: 10.1101/lm.038513.115
Boccia, M.M., Blake, M.G., Acosta, G.B., Baratti, C.M. Memory consolidation and reconsolidation of an inhibitory avoidance task in mice: Effects of a new different learning task (2005) Neuroscience, 135 (1), pp. 19-29. Cited 38 times. DOI: 10.1016/j.neuroscience.2005.04.068
Díaz-Mataix, L., Ruiz Martinez, R.C., Schafe, G.E., Ledoux, J.E., Doyère, V. Detection of a temporal error triggers reconsolidation of amygdala-dependent memories (2013) Current Biology, 23 (6), pp. 467-472. Cited 96 times. DOI: 10.1016/j.cub.2013.01.053
Liu, J., Zhao, L., Xue, Y., Shi, J., Suo, L., Luo, Y., Chai, B., Yang, C., Fang, Q., Zhang, Y., Bao, Y., Pickens, C.L., Lu, L. An unconditioned stimulus retrieval extinction procedure to prevent the return of fear memory (2014) Biological Psychiatry, 76 (11), pp. 895-901. Cited 57 times. DOI: 10.1016/j.biopsych.2014.03.027
Reichelt, A.C., Exton-McGuinness, M.T., Lee, J.L.C. Ventral tegmental dopamine dysregulation prevents appetitive memory destabilization (2013) Journal of Neuroscience, 33 (35), pp. 14205-14210. Cited 33 times. DOI: 10.1523/JNEUROSCI.1614-13.2013
Winters, B.D., Tucci, M.C., Jacklin, D.L., Reid, J.M., Newsome, J. On the dynamic nature of the engram: Evidence for circuit-level reorganization of object memory traces following reactivation (2011) Journal of Neuroscience, 31 (48), pp. 17719-17728. Cited 44 times. DOI: 10.1523/JNEUROSCI.2968-11.2011
Baratti, C.M., Boccia, M.M., Blake, M.G., Acosta, G.B. Reactivated memory of an inhibitory avoidance response in mice is sensitive to a nitric oxide synthase inhibitor (2008) Neurobiology of Learning and Memory, 89 (4), pp. 426-440. Cited 22 times. DOI: 10.1016/j.nlm.2007.11.001
Eisenberg, M., Dudai, Y. Reconsolidation of fresh, remote, and extinguished fear memory in medaka: Old fears don't die (2004) European Journal of Neuroscience, 20 (12), pp. 3397-3403. Cited 150 times. DOI: 10.1111/j.1460-9568.2004.03818.x
Forcato, C., Fernandez, R.S., Pedreira, M.E. The Role and Dynamic of Strengthening in the Reconsolidation Process in a Human Declarative Memory: What Decides the Fate of Recent and Older Memories? (2013) PLoS ONE, 8 (4), art. no. e61688, . Cited 29 times. DOI: 10.1371/journal.pone.0061688
Wang, S.-H., De Oliveira Alvares, L., Nader, K. Cellular and systems mechanisms of memory strength as a constraint on auditory fear reconsolidation (2009) Nature Neuroscience, 12 (7), pp. 905-912. Cited 199 times. DOI: 10.1038/nn.2350
Suzuki, A., Josselyn, S.A., Frankland, P.W., Masushige, S., Silva, A.J., Kida, S. Memory reconsolidation and extinction have distinct temporal and biochemical signatures (2004) Journal of Neuroscience, 24 (20), pp. 4787-4795. Cited 812 times. DOI: 10.1523/JNEUROSCI.5491-03.2004
Milekic, M.H., Alberini, C.M. Temporally graded requirement for protein synthesis following memory reactivation (2002) Neuron, 36 (3), pp. 521-525. Cited 355 times. DOI: 10.1016/S0896-6273(02)00976-5
Inda, M.C., Muravieva, E.V., Alberini, C.M. Memory retrieval and the passage of time: From reconsolidation and strengthening to extinction (2011) Journal of Neuroscience, 31 (5), pp. 1635-1643. Cited 191 times. DOI: 10.1523/JNEUROSCI.4736-10.2011
Pavlov, I.P. (1927) Conditioned Reflexes. Cited 4609 times.
Bouton, M.E., Mineka, S., Barlow, D.H. A modern learning theory perspective on the etiology of panic disorder (2001) Psychological Review, 108 (1), pp. 4-32. Cited 718 times. DOI: 10.1037/0033-295X.108.1.4
LeDoux, J.E., Pine, D.S. Using neuroscience to help understand fear and anxiety: A two-system framework (2016) American Journal of Psychiatry, 173 (11), pp. 1083-1093. Cited 247 times. DOI: 10.1176/appi.ajp.2016.16030353
Nader, K., Hardt, O., Lanius, R. Memory as a new therapeutic target (2013) Dialogues in Clinical Neuroscience, 15 (4), pp. 475-486. Cited 37 times
Kindt, M. The surprising subtleties of changing fear memory: A challenge for translational science (2018) Philosophical Transactions of the Royal Society B: Biological Sciences, 373 (1742), art. no. 20170033, 8 p. Cited 22 times. DOI: 10.1098/rstb.2017.0033
Lane, R.D., Ryan, L., Nadel, L., Greenberg, L. Memory reconsolidation, emotional arousal, and the process of change in psychotherapy: New insights from brain science (2015) Behavioral and Brain Sciences, 38, art. no. e1, . Cited 170 times. DOI: 10.1017/S0140525X14000041
Soeter, M., Kindt, M. An Abrupt Transformation of Phobic Behavior after a Post-Retrieval Amnesic Agent (2015) Biological Psychiatry, 78 (12), pp. 880-886. Cited 98 times. DOI: 10.1016/j.biopsych.2015.04.006
Monfils, M.H., Holmes, E.A. Memory boundaries: opening a window inspired by reconsolidation to treat anxiety, trauma-related, and addiction disorders (2018) The Lancet Psychiatry, 5 (12), pp. 1032-1042. Cited 28 times. DOI: 10.1016/S2215-0366(18)30270-0
Tollenaar, M.S., Elzinga, B.M., Spinhoven, P., Everaerd, W. Psychophysiological responding to emotional memories in healthy young men after cortisol and propranolol administration (2009) Psychopharmacology, 203 (4), pp. 793-803. Cited 34 times. DOI: 10.1007/s00213-008-1427-x
Saladin, M.E., Gray, K.M., McRae-Clark, A.L., Larowe, S.D., Yeatts, S.D., Baker, N.L., Hartwell, K.J., Brady, K.T. A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans (2013) Psychopharmacology, 226 (4), pp. 721-737. Cited 61 times. DOI: 10.1007/s00213-013-3039-3
Lonergan, M., Saumier, D., Tremblay, J., Kieffer, B., Brown, T.G., Brunet, A. Reactivating addiction-related memories under propranolol to reduce craving: A pilot randomized controlled trial (2016) Journal of Behavior Therapy and Experimental Psychiatry, 50, pp. 245-249. Cited 35 times. DOI: 10.1016/j.jbtep.2015.09.012
Das, R.K., Hindocha, C., Freeman, T.P., Lazzarino, A.I., Curran, H.V., Kamboj, S.K. Assessing the translational feasibility of pharmacological drug memory reconsolidation blockade with memantine in quitting smokers (2015) Psychopharmacology, 232 (18), pp. 3363-3374. Cited 21 times. DOI: 10.1007/s00213-015-3990-2
Germeroth, L.J., Carpenter, M.J., Baker, N.L., Froeliger, B., LaRowe, S.D., Saladin, M.E. Effect of a brief memory updating intervention on smoking behavior: A randomized clinical trial (2017) JAMA Psychiatry, 74 (3), pp. 214-223. Cited 36 times. DOI: 10.1001/jamapsychiatry.2016.3148
Xue, Y.-X., Deng, J.-H., Chen, Y.-Y., Zhang, L.-B., Huang, G.-D., Luo, Y.-X., Bao, Y.-P., Wang, Y.-M., Shaham, Y., Shi, J., Lu, L. Effect of selective inhibition of reactivated nicotine-associated memories with propranolol on nicotine craving (2017) JAMA Psychiatry, 74 (3), pp. 224-232. Cited 35 times. DOI: 10.1001/jamapsychiatry.2016.3907
Xue, Y.-X., Luo, Y.-X., Wu, P., Shi, H.-S., Xue, L.-F., Chen, C., Zhu, W.-L., Ding, Z.-B., Bao, Y.-P., Shi, J., Epstein, D.H., Shaham, Y., Lu, L. A memory retrieval-extinction procedure to prevent drug craving and relapse (2012) Science, 336 (6078), pp. 241-245. Cited 309 times. DOI: 10.1126/science.1215070
Agren, T., Engman, J., Frick, A., Björkstrand, J., Larsson, E.-M., Furmark, T., Fredrikson, M. Disruption of reconsolidation erases a fear memory trace in the human amygdala (2012) Science, 337 (6101), pp. 1550-1552. Cited 198 times. DOI: 10.1126/science.1223006
Das, R.K., Lawn, W., Kamboj, S.K. Rewriting the valuation and salience of alcohol-related stimuli via memory reconsolidation (2015) Translational Psychiatry, 5 (9), art. no. e645, . Cited 50 times. DOI: 10.1038/tp.2015.132
Brunet, A., Thomas, É., Saumier, D., Ashbaugh, A.R., Azzoug, A., Pitman, R.K., Orr, S.P., Tremblay, J. Trauma reactivation plus propranolol is associated with durably low physiological responding during subsequent script-driven traumatic imagery (2014) Canadian Journal of Psychiatry, 59 (4), pp. 228-232. Cited 39 times. DOI: 10.1177/070674371405900408
Tollenaar, M.S., Elzinga, B.M., Spinhoven, P., Everaerd, W. Psychophysiological responding to emotional memories in healthy young men after cortisol and propranolol administration (2009) Psychopharmacology, 203 (4), pp. 793-803. Cited 34 times. DOI: 10.1007/s00213-008-1427-x
Maples-Keller, J.L., Price, M., Jovanovic, T., Norrholm, S.D., Odenat, L., Post, L., Zwiebach, L., Breazeale, K., Gross, R., Kim, S.-J., Rothbaum, B.O. Targeting memory reconsolidation to prevent the return of fear in patients with fear of flying (2017) Depression and Anxiety, 34 (7), pp. 610-620. Cited 21 times. DOI: 10.1002/da.22626
Telch, M.J., York, J., Lancaster, C.L., Monfils, M.H. Use of a Brief Fear Memory Reactivation Procedure for Enhancing Exposure Therapy (2017) Clinical Psychological Science, 5 (2), pp. 367-378. Cited 20 times. DOI: 10.1177/2167702617690151
Fernández, R.S., Bavassi, L., Forcato, C., Pedreira, M.E. The dynamic nature of the reconsolidation process and its boundary conditions: Evidence based on human tests (2016) Neurobiology of Learning and Memory, 130, pp. 202-212. Cited 13 times. DOI: 10.1016/j.nlm.2016.03.001
Wymbs, N.F., Bastian, A.J., Celnik, P.A. Motor skills are strengthened through reconsolidation (2016) Current Biology, 26 (3), pp. 338-343. Cited 31 times. DOI: 10.1016/j.cub.2015.11.066
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spelling Fernández, Rodrigo SAllegri, Ricardo2020-11-24T16:24:48Z2020-11-24T16:24:48Z2019https://hdl.handle.net/11323/7454https://doi.org/10.1016/j.neuarg.2019.06.002Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Introducción En condiciones normales, nuestro cerebro es capaz de actualizar sus representaciones almacenadas en fuerza o contenido por el proceso de reconsolidación. De esta forma, una memoria consolidada es reactivada y entra en un periodo transitorio de inestabilidad seguido por una fase de reestabilización para persistir. El inicio del proceso de reconsolidación depende de la detección de una incongruencia entre la predicción realizada y lo ocurrido (error de predicción), en el que la predicción inicial se ajusta acorde al error generado. Desarrollo La neurociencia, la psicología y otras ciencias básicas han aportado perspectivas novedosas en la investigación y abordaje de diversos trastornos psiquiátricos. En este sentido, establecieron una relación íntima entre la memoria y las enfermedades mentales. El paradigma de la reconsolidación de la memoria ha sido propuesto no solo como el mecanismo responsable del mantenimiento de algunas psicopatologías sino también como una oportunidad de establecer nuevos tratamientos. En la presente revisión se desarrollará el concepto de reconsolidación, ampliamente estudiado en animales y humanos en los últimos 20 años, y se destacarán sus potenciales aplicaciones traslacionales a la clínica neuropsiquiátrica. Conclusiones Existen evidencias de que el proceso de reconsolidación tendría utilidad terapéutica en la clínica neuropsiquiátrica. Sin embargo, aún se requieren estudios mayores y más complejos.Fernández, Rodrigo S-will be generated-orcid-0000-0002-0213-9108-600Allegri, Ricardoapplication/pdfspaCorporación Universidad de la CostaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Neurología Argentinahttps://www.sciencedirect.com/science/article/abs/pii/S1853002819300473?via%3DihubMemoriaReconsolidaciónConsolidaciónError de predicciónTraslacionalNeuropsiquiatríaAcerca de la inestabilidad de las memorias y su transformación por el proceso de reconsolidación: aportes para su consideración clínicaOn the instability of memories and its transformation by the reconsolidation process: Contributions for its clinical considerationArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionBubic, A., Yves von Cramon, D., Schubotz, R.I. Prediction, cognition and the brain (2010) Frontiers in Human Neuroscience, 4, . Cited 321 times. DOI: 10.3389/fnhum.2010.00025Buzsáki, G., Peyrache, A., Kubie, J. Emergence of cognition from action (2014) Cold Spring Harbor Symposia on Quantitative Biology, 79, pp. 41-50. Cited 33 times. DOI: 10.1101/sqb.2014.79.024679Dudai, Y. (2002) Memory from A to Z. Keywords, Concepts and Beyond. Cited 133 times.Squire, L.R., Genzel, L., Wixted, J.T., Morris, R.G. Memory consolidation (2015) Cold Spring Harbor Perspectives in Biology, 7 (8), 21 p. Cited 150 times. DOI: 10.1101/cshperspect.a021766Kandel, E.R. The molecular biology of memory storage: A dialog between genes and synapses (2001) Bioscience Reports, 21 (5), pp. 565-611. Cited 239 times. DOI: 10.1023/AMcGaugh, J.L. Memory - A century of consolidation (2000) Science, 287 (5451), pp. 248-251. Cited 2890 times. DOI: 10.1126/science.287.5451.248Abel, T., Lattal, K.M. Molecular mechanisms of memory acquisition, consolidation and retrieval (2001) Current Opinion in Neurobiology, 11 (2), pp. 180-187. Cited 500 times. DOI: 10.1016/S0959-4388(00)00194-XKitamura, T., Ogawa, S.K., Roy, D.S., Okuyama, T., Morrissey, M.D., Smith, L.M., Redondo, R.L., Tonegawa, S. Engrams and circuits crucial for systems consolidation of a memory (2017) Science, 356 (6333), pp. 73-78. Cited 256 times. DOI: 10.1126/science.aam6808Gilboa, A., Marlatte, H. Neurobiology of Schemas and Schema-Mediated Memory (2017) Trends in Cognitive Sciences, 21 (8), pp. 618-631. Cited 129 times. DOI: 10.1016/j.tics.2017.04.013Dudai, Y. Predicting not to predict too much: How the cellular machinery of memory anticipates the uncertain future (2009) Philosophical Transactions of the Royal Society B: Biological Sciences, 364 (1521), pp. 1255-1262. Cited 59 times. DOI: 10.1098/rstb.2008.0320Niv, Y Reinforcement learning in the brain (2009) Journal of Mathematical Psychology, 53 (3), pp. 139-154. Cited 237 times. DOI: 10.1016/j.jmp.2008.12.005Nader, K. Reconsolidation and the dynamic nature of memory (2015) Cold Spring Harbor Perspectives in Biology, 7 (10), art. no. a021782, 17 p. Cited 69 times. DOI: 10.1101/cshperspect.a021782Den Ouden, H.E.M., Friston, K.J., Daw, N.D., McIntosh, A.R., Stephan, K.E. A dual role for prediction error in associative learning (2009) Cerebral Cortex, 19 (5), pp. 1175-1185. Cited 193 times. DOI: 10.1093/cercor/bhn161Fernández, R.S., Pedreira, M.E., Boccia, M.M. Does reconsolidation occur in natural settings? Memory reconsolidation and anxiety disorders (2017) Clinical Psychology Review, 57, pp. 45-58. Cited 9 times. DOI: 10.1016/j.cpr.2017.08.004Gershman, S.J., Monfils, M.-H., Norman, K.A., Niv, Y. The computational nature of memory modification (2017) eLife, 6, art. no. e23763, . Cited 41 times. DOI: 10.7554/eLife.23763Bouton, M.E. Context, time, and memory retrieval in the interference paradigms of pavlovian learning (1993) Psychological Bulletin, 114 (1), pp. 80-99. Cited 1342 times. DOI: 10.1037/0033-2909.114.1.80Gordon, W.C. Mechanisms of cue-induced retention enhancement (1981) Information Processing in Animals: Memory Mechanisms, pp. 319-339. Cited 78 times.Fernández, R.S., Boccia, M.M., Pedreira, M.E. The fate of memory: Reconsolidation and the case of Prediction Error (2016) Neuroscience and Biobehavioral Reviews, 68, pp. 423-441. Cited 59 times. DOI: 10.1016/j.neubiorev.2016.06.004Forcato, C., Fernandez, R.S., Pedreira, M.E. Strengthening a consolidated memory: The key role of the reconsolidation process (2014) Journal of Physiology Paris, 108 (4-6), pp. 323-333. Cited 38 times. DOI: 10.1016/j.jphysparis.2014.09.001Dudai, Y. The restless engram: Consolidations never end (2012) Annual Review of Neuroscience, 35, pp. 227-247. Cited 329 times. DOI: 10.1146/annurev-neuro-062111-150500Fernández, R.S., Bavassi, L., Kaczer, L., Forcato, C., Pedreira, M.E. Interference conditions of the reconsolidation process in humans: The role of valence and different memory systems (2016) Frontiers in Human Neuroscience, 10 (DEC2016), art. no. 641, . Cited 7 times. DOI: 10.3389/fnhum.2016.00641Hassabis, D., Maguire, E.A. Deconstructing episodic memory with construction (2007) Trends in Cognitive Sciences, 11 (7), pp. 299-306. Cited 663 times. DOI: 10.1016/j.tics.2007.05.001Lewis, D.J. Psychobiology of active and inactive memory (1979) Psychological Bulletin, 86 (5), pp. 1054-1083. Cited 354 times. DOI: 10.1037/0033-2909.86.5.1054Misanin, J.R., Miller, R.R., Lewis, D.J. Retrograde amnesia produced by electroconvulsive shock after reactivation of a consolidated memory trace (1968) Science, 160 (3827), pp. 554-555. Cited 591 times. DOI: 10.1126/science.160.3827.554Spear, N.E. Retrieval of memory in animals (1973) Psychological Review, 80 (3), pp. 163-194. Cited 384 times. DOI: 10.1037/h0034326Przybyslawski, J., Sara, S.J. Reconsolidation of memory after its reactivation (1997) Behavioural Brain Research, 84 (1-2), pp. 241-246. Cited 355 times. DOI: 10.1016/S0166-4328(96)00153-2Nader, K., Schafe, G.E., Le Doux, J.E. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval (2000) Nature, 406 (6797), pp. 722-726. Cited 1710 times. DOI: 10.1038/35021052Alberini, C. Memory Reconsolidation (2013) Memory Reconsolidation, 320 p. Cited 13 times. DOI: 10.1016/C2010-0-67992-2Boccia, M.M., Blake, M.G., Krawczyk, M.C., Baratti, C.M. Hippocampal alpha7 nicotinic receptors modulate memory reconsolidation of an inhibitory avoidance task in mice (2010) Neuroscience, 171 (2), pp. 531-543. Cited 37 times. DOI: 10.1016/j.neuroscience.2010.08.027Krawczyk, M.C., Fernández, R.S., Pedreira, M.E., Boccia, M.M. Toward a better understanding on the role of prediction error on memory processes: From bench to clinic (2017) Neurobiology of Learning and Memory, 142, pp. 13-20. Cited 15 times. DOI: 10.1016/j.nlm.2016.12.011Lee, J.L.C. Memory reconsolidation mediates the updating of hippocampal memory content (2010) Frontiers in Behavioral Neuroscience, 4 (NOV), art. no. 168, . Cited 116 times. DOI: 10.3389/fnbeh.2010.00168Pedreira, M.E., Pérez-Cuesta, L.M., Maldonado, H. Mismatch between what is expected and what actually occurs triggers memory reconsolidation or extinction (2004) Learning and Memory, 11 (5), pp. 579-585. Cited 250 times. DOI: 10.1101/lm.76904Schiller, D., Monfils, M.-H., Raio, C.M., Johnson, D.C., Ledoux, J.E., Phelps, E.A. Preventing the return of fear in humans using reconsolidation update mechanisms (2010) Nature, 463 (7277), pp. 49-53. Cited 752 times. DOI: 10.1038/nature08637Alberini, C.M. Mechanisms of memory stabilization: Are consolidation and reconsolidation similar or distinct processes? (2005) Trends in Neurosciences, 28 (1), pp. 51-56. Cited 450 times. DOI: 10.1016/j.tins.2004.11.001Finnie, P.S.B., Nader, K. The role of metaplasticity mechanisms in regulating memory destabilization and reconsolidation (2012) Neuroscience and Biobehavioral Reviews, 36 (7), pp. 1667-1707. Cited 116 times. DOI: 10.1016/j.neubiorev.2012.03.008Flavell, C.R., Lambert, E.A., Winters, B.D., Bredy, T.W. Mechanisms governing the reactivation-dependent destabilization of memories and their role in extinction (2013) Frontiers in Behavioral Neuroscience, 7 (DEC), . Cited 28 times. DOI: 10.3389/fnbeh.2013.00214Alberini, C.M., Ledoux, J.E. Memory reconsolidation (2013) Current Biology, 23 (17), pp. R746-R750. Cited 123 times. DOI: 10.1016/j.cub.2013.06.046Tronson, N.C., Taylor, J.R. Molecular mechanisms of memory reconsolidation (2007) Nature Reviews Neuroscience, 8 (4), pp. 262-275. Cited 556 times. DOI: 10.1038/nrn2090Exton-McGuinness, M.T.J., Patton, R.C., Sacco, L.B., Lee, J.L.C. Reconsolidation of a well-learned instrumental memory (2014) Learning and Memory, 21 (9), pp. 468-477. Cited 35 times. DOI: 10.1101/lm.035543.114Pedreira, M.E., Maldonado, H. Protein synthesis subserves reconsolidation or extinction depending on reminder duration (2003) Neuron, 38 (6), pp. 863-869. Cited 321 times. DOI: 10.1016/S0896-6273(03)00352-0Rescorla, R.A., Wagner, A.R. A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement (1972) Classical Conditioning II: Current Research and Theory, pp. 64-99. Cited 5698 timesDe Oliveira Alvares, L., Crestani, A.P., Cassini, L.F., Haubrich, J., Santana, F., Quillfeldt, J.A. Reactivation enables memory updating, precision-keeping and strengthening: Exploring the possible biological roles of reconsolidation (2013) Neuroscience, 244, pp. 42-48. Cited 66 times. DOI: 10.1016/j.neuroscience.2013.04.005Forcato, C., Argibay, P.F., Pedreira, M.E., Maldonado, H. Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure (2009) Neurobiology of Learning and Memory, 91 (1), pp. 50-57. Cited 109 times. DOI: 10.1016/j.nlm.2008.09.011Kindt, M., Soeter, M., Vervliet, B. Beyond extinction: Erasing human fear responses and preventing the return of fear (2009) Nature Neuroscience, 12 (3), pp. 256-258. Cited 523 times. DOI: 10.1038/nn.2271Alfei, J.M., Monti, R.I.F., Molina, V.A., Bueno, A.M., Urcelay, G.P. Prediction error and trace dominance determine the fate of fear memories after post-training manipulations (2015) Learning and Memory, 22 (8), pp. 385-400. Cited 38 times. DOI: 10.1101/lm.038513.115Boccia, M.M., Blake, M.G., Acosta, G.B., Baratti, C.M. Memory consolidation and reconsolidation of an inhibitory avoidance task in mice: Effects of a new different learning task (2005) Neuroscience, 135 (1), pp. 19-29. Cited 38 times. DOI: 10.1016/j.neuroscience.2005.04.068Díaz-Mataix, L., Ruiz Martinez, R.C., Schafe, G.E., Ledoux, J.E., Doyère, V. Detection of a temporal error triggers reconsolidation of amygdala-dependent memories (2013) Current Biology, 23 (6), pp. 467-472. Cited 96 times. DOI: 10.1016/j.cub.2013.01.053Liu, J., Zhao, L., Xue, Y., Shi, J., Suo, L., Luo, Y., Chai, B., Yang, C., Fang, Q., Zhang, Y., Bao, Y., Pickens, C.L., Lu, L. An unconditioned stimulus retrieval extinction procedure to prevent the return of fear memory (2014) Biological Psychiatry, 76 (11), pp. 895-901. Cited 57 times. DOI: 10.1016/j.biopsych.2014.03.027Reichelt, A.C., Exton-McGuinness, M.T., Lee, J.L.C. Ventral tegmental dopamine dysregulation prevents appetitive memory destabilization (2013) Journal of Neuroscience, 33 (35), pp. 14205-14210. Cited 33 times. DOI: 10.1523/JNEUROSCI.1614-13.2013Winters, B.D., Tucci, M.C., Jacklin, D.L., Reid, J.M., Newsome, J. On the dynamic nature of the engram: Evidence for circuit-level reorganization of object memory traces following reactivation (2011) Journal of Neuroscience, 31 (48), pp. 17719-17728. Cited 44 times. DOI: 10.1523/JNEUROSCI.2968-11.2011Baratti, C.M., Boccia, M.M., Blake, M.G., Acosta, G.B. Reactivated memory of an inhibitory avoidance response in mice is sensitive to a nitric oxide synthase inhibitor (2008) Neurobiology of Learning and Memory, 89 (4), pp. 426-440. Cited 22 times. DOI: 10.1016/j.nlm.2007.11.001Eisenberg, M., Dudai, Y. Reconsolidation of fresh, remote, and extinguished fear memory in medaka: Old fears don't die (2004) European Journal of Neuroscience, 20 (12), pp. 3397-3403. Cited 150 times. DOI: 10.1111/j.1460-9568.2004.03818.xForcato, C., Fernandez, R.S., Pedreira, M.E. The Role and Dynamic of Strengthening in the Reconsolidation Process in a Human Declarative Memory: What Decides the Fate of Recent and Older Memories? (2013) PLoS ONE, 8 (4), art. no. e61688, . Cited 29 times. DOI: 10.1371/journal.pone.0061688Wang, S.-H., De Oliveira Alvares, L., Nader, K. Cellular and systems mechanisms of memory strength as a constraint on auditory fear reconsolidation (2009) Nature Neuroscience, 12 (7), pp. 905-912. Cited 199 times. DOI: 10.1038/nn.2350Suzuki, A., Josselyn, S.A., Frankland, P.W., Masushige, S., Silva, A.J., Kida, S. Memory reconsolidation and extinction have distinct temporal and biochemical signatures (2004) Journal of Neuroscience, 24 (20), pp. 4787-4795. Cited 812 times. DOI: 10.1523/JNEUROSCI.5491-03.2004Milekic, M.H., Alberini, C.M. Temporally graded requirement for protein synthesis following memory reactivation (2002) Neuron, 36 (3), pp. 521-525. Cited 355 times. DOI: 10.1016/S0896-6273(02)00976-5Inda, M.C., Muravieva, E.V., Alberini, C.M. Memory retrieval and the passage of time: From reconsolidation and strengthening to extinction (2011) Journal of Neuroscience, 31 (5), pp. 1635-1643. Cited 191 times. DOI: 10.1523/JNEUROSCI.4736-10.2011Pavlov, I.P. (1927) Conditioned Reflexes. Cited 4609 times.Bouton, M.E., Mineka, S., Barlow, D.H. A modern learning theory perspective on the etiology of panic disorder (2001) Psychological Review, 108 (1), pp. 4-32. Cited 718 times. DOI: 10.1037/0033-295X.108.1.4LeDoux, J.E., Pine, D.S. Using neuroscience to help understand fear and anxiety: A two-system framework (2016) American Journal of Psychiatry, 173 (11), pp. 1083-1093. Cited 247 times. DOI: 10.1176/appi.ajp.2016.16030353Nader, K., Hardt, O., Lanius, R. Memory as a new therapeutic target (2013) Dialogues in Clinical Neuroscience, 15 (4), pp. 475-486. Cited 37 timesKindt, M. The surprising subtleties of changing fear memory: A challenge for translational science (2018) Philosophical Transactions of the Royal Society B: Biological Sciences, 373 (1742), art. no. 20170033, 8 p. Cited 22 times. DOI: 10.1098/rstb.2017.0033Lane, R.D., Ryan, L., Nadel, L., Greenberg, L. Memory reconsolidation, emotional arousal, and the process of change in psychotherapy: New insights from brain science (2015) Behavioral and Brain Sciences, 38, art. no. e1, . Cited 170 times. DOI: 10.1017/S0140525X14000041Soeter, M., Kindt, M. An Abrupt Transformation of Phobic Behavior after a Post-Retrieval Amnesic Agent (2015) Biological Psychiatry, 78 (12), pp. 880-886. Cited 98 times. DOI: 10.1016/j.biopsych.2015.04.006Monfils, M.H., Holmes, E.A. Memory boundaries: opening a window inspired by reconsolidation to treat anxiety, trauma-related, and addiction disorders (2018) The Lancet Psychiatry, 5 (12), pp. 1032-1042. Cited 28 times. DOI: 10.1016/S2215-0366(18)30270-0Tollenaar, M.S., Elzinga, B.M., Spinhoven, P., Everaerd, W. Psychophysiological responding to emotional memories in healthy young men after cortisol and propranolol administration (2009) Psychopharmacology, 203 (4), pp. 793-803. Cited 34 times. DOI: 10.1007/s00213-008-1427-xSaladin, M.E., Gray, K.M., McRae-Clark, A.L., Larowe, S.D., Yeatts, S.D., Baker, N.L., Hartwell, K.J., Brady, K.T. A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans (2013) Psychopharmacology, 226 (4), pp. 721-737. Cited 61 times. DOI: 10.1007/s00213-013-3039-3Lonergan, M., Saumier, D., Tremblay, J., Kieffer, B., Brown, T.G., Brunet, A. Reactivating addiction-related memories under propranolol to reduce craving: A pilot randomized controlled trial (2016) Journal of Behavior Therapy and Experimental Psychiatry, 50, pp. 245-249. Cited 35 times. DOI: 10.1016/j.jbtep.2015.09.012Das, R.K., Hindocha, C., Freeman, T.P., Lazzarino, A.I., Curran, H.V., Kamboj, S.K. Assessing the translational feasibility of pharmacological drug memory reconsolidation blockade with memantine in quitting smokers (2015) Psychopharmacology, 232 (18), pp. 3363-3374. Cited 21 times. DOI: 10.1007/s00213-015-3990-2Germeroth, L.J., Carpenter, M.J., Baker, N.L., Froeliger, B., LaRowe, S.D., Saladin, M.E. Effect of a brief memory updating intervention on smoking behavior: A randomized clinical trial (2017) JAMA Psychiatry, 74 (3), pp. 214-223. Cited 36 times. DOI: 10.1001/jamapsychiatry.2016.3148Xue, Y.-X., Deng, J.-H., Chen, Y.-Y., Zhang, L.-B., Huang, G.-D., Luo, Y.-X., Bao, Y.-P., Wang, Y.-M., Shaham, Y., Shi, J., Lu, L. Effect of selective inhibition of reactivated nicotine-associated memories with propranolol on nicotine craving (2017) JAMA Psychiatry, 74 (3), pp. 224-232. Cited 35 times. DOI: 10.1001/jamapsychiatry.2016.3907Xue, Y.-X., Luo, Y.-X., Wu, P., Shi, H.-S., Xue, L.-F., Chen, C., Zhu, W.-L., Ding, Z.-B., Bao, Y.-P., Shi, J., Epstein, D.H., Shaham, Y., Lu, L. A memory retrieval-extinction procedure to prevent drug craving and relapse (2012) Science, 336 (6078), pp. 241-245. Cited 309 times. DOI: 10.1126/science.1215070Agren, T., Engman, J., Frick, A., Björkstrand, J., Larsson, E.-M., Furmark, T., Fredrikson, M. Disruption of reconsolidation erases a fear memory trace in the human amygdala (2012) Science, 337 (6101), pp. 1550-1552. Cited 198 times. DOI: 10.1126/science.1223006Das, R.K., Lawn, W., Kamboj, S.K. Rewriting the valuation and salience of alcohol-related stimuli via memory reconsolidation (2015) Translational Psychiatry, 5 (9), art. no. e645, . Cited 50 times. DOI: 10.1038/tp.2015.132Brunet, A., Thomas, É., Saumier, D., Ashbaugh, A.R., Azzoug, A., Pitman, R.K., Orr, S.P., Tremblay, J. Trauma reactivation plus propranolol is associated with durably low physiological responding during subsequent script-driven traumatic imagery (2014) Canadian Journal of Psychiatry, 59 (4), pp. 228-232. Cited 39 times. DOI: 10.1177/070674371405900408Tollenaar, M.S., Elzinga, B.M., Spinhoven, P., Everaerd, W. Psychophysiological responding to emotional memories in healthy young men after cortisol and propranolol administration (2009) Psychopharmacology, 203 (4), pp. 793-803. Cited 34 times. DOI: 10.1007/s00213-008-1427-xMaples-Keller, J.L., Price, M., Jovanovic, T., Norrholm, S.D., Odenat, L., Post, L., Zwiebach, L., Breazeale, K., Gross, R., Kim, S.-J., Rothbaum, B.O. Targeting memory reconsolidation to prevent the return of fear in patients with fear of flying (2017) Depression and Anxiety, 34 (7), pp. 610-620. Cited 21 times. DOI: 10.1002/da.22626Telch, M.J., York, J., Lancaster, C.L., Monfils, M.H. Use of a Brief Fear Memory Reactivation Procedure for Enhancing Exposure Therapy (2017) Clinical Psychological Science, 5 (2), pp. 367-378. Cited 20 times. DOI: 10.1177/2167702617690151Fernández, R.S., Bavassi, L., Forcato, C., Pedreira, M.E. The dynamic nature of the reconsolidation process and its boundary conditions: Evidence based on human tests (2016) Neurobiology of Learning and Memory, 130, pp. 202-212. Cited 13 times. DOI: 10.1016/j.nlm.2016.03.001Wymbs, N.F., Bastian, A.J., Celnik, P.A. Motor skills are strengthened through reconsolidation (2016) Current Biology, 26 (3), pp. 338-343. Cited 31 times. 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