Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021

: ilustraciones, gráficos, tablas ; 28 cm.

Autores:
Beltrán Castro, Marvin Stiven
Tipo de recurso:
Fecha de publicación:
2022
Institución:
Fundación Universitaria del Área Andina
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Repositorio Digital Areandina
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spa
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oai:digitk.areandina.edu.co:areandina/6294
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https://digitk.areandina.edu.co/handle/areandina/6294
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repository_id_str
dc.title.spa.fl_str_mv Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
title Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
spellingShingle Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
title_short Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
title_full Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
title_fullStr Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
title_full_unstemmed Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
title_sort Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021
dc.creator.fl_str_mv Beltrán Castro, Marvin Stiven
dc.contributor.advisor.none.fl_str_mv Totora Rodríguez, Juan Camilo
dc.contributor.author.none.fl_str_mv Beltrán Castro, Marvin Stiven
description : ilustraciones, gráficos, tablas ; 28 cm.
publishDate 2022
dc.date.available.none.fl_str_mv 2022-09-03
2025-04-23T17:07:35Z
dc.date.issued.none.fl_str_mv 2022-10-19
dc.date.accessioned.none.fl_str_mv 2025-04-23T17:07:35Z
dc.type.none.fl_str_mv Trabajo de grado - Especialización
dc.type.content.none.fl_str_mv Text
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.uri.none.fl_str_mv https://digitk.areandina.edu.co/handle/areandina/6294
url https://digitk.areandina.edu.co/handle/areandina/6294
dc.language.iso.none.fl_str_mv spa
language spa
dc.relation.references.none.fl_str_mv 1. Moya L, Moreno J, Lombo M, Guerrero C, Aristizábal D, Vera A, et al. Expert consensus on the clinical management of arterial hypertension in Colombia Colombian Society of Cardiology and Cardiovascular Surgery. Rev Colomb Cardiol [Internet]. 2018;25:4–26. Available from: https://doi.org/10.1016/j.rccar.2018.09.002 2. Mills KT, Bundy JD, Kelly TN, Reed JE, Kearney PM, Reynolds K. Global Disparities of Hypertension Prevalence and Control A Systematic Analysis of Population-Based Studies From 90 Countries. Circulation. 2016;441–50. 3. Mahfoud F, Böhm M, Bongarth CM, Bosch R, Schmieder RE, Schunkert H, et al. Comments on the guidelines (2018) of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH) on the management of arterial hypertension. Vol. 60, Internist. Springer Verlag; 2019. p. 424–30. 4. A global brief on hypertension | A global brief on Hyper tension [Internet]. 2013 [cited 2020 Apr 17]. Available from: www.who.int 5. Rosas-Peralta M, Borrayo-Sánchez G, Madrid-Miller A, Ramírez-Arias E, Pérez- Rodríguez G. Complicaciones cardiovasculares de la crisis hipertensiva. Rev Med Inst Mex Seguro Soc. 2016;54. 6. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National
Committee (JNC 8). JAMA - J Am Med Assoc. 2014;311(5):507–20. 7. Cortés Fernández M del S, Segura J. Should all hypertensive emergencies be treated in the same way? Hipertens y Riesgo Vasc. 2019 Jul 1;36(3):119–21. 8. Brathwaite L, Reif M. Hypertensive Emergencies: A Review of Common Presentations and Treatment Options. Vol. 37, Cardiology Clinics. W.B. Saunders; 2019. p. 275–86. 9. Kallikazaros IE. Arterial Hypertension. Hell J Cardiol HJC • 413 Hell J Cardiol. 2013;54:413–6. 10. Hui R. Hypertension Drug Therapy. In Springer, Singapore; 2020. p. 149–268. 11. Albaladejo Blanco C, Sobrino Martínez J, Vázquez González S. Crisis hipertensivas: Seudocrisis, urgencias y emergencias. Hipertens y Riesgo Vasc [Internet]. 2014;31(4):132–42. Available from: http://dx.doi.org/10.1016/j.hipert.2014.04.001 12. Pierin AMG, Flórido CF, Santos J dos, Pierin AMG, Flórido CF, Santos J dos. Hypertensive crisis: clinical characteristics of patients with hypertensive urgency, emergency and pseudocrisis at a public emergency department. Einstein (São Paulo). 2019;17(4). 13. Paini A, Aggiusti C, Bertacchini F, Agabiti Rosei C, Maruelli G, Arnoldi C, et al. Definitions and Epidemiological Aspects of Hypertensive Urgencies and Emergencies. Vol. 25, High Blood Pressure and Cardiovascular Prevention. Springer International Publishing; 2018. p. 241–4. 14. Van den Born B-JH, Lip GYH, Brguljan-Hitij J, Cremer A, Segura J, Morales E, et al.
ESC Council on hypertension position document on the management of hypertensive emergencies. Eur Hear J - Cardiovasc Pharmacother. 2019 Jan 1;5(1):37–46. 15. Cortés Fernández M, Segura J. Should all hypertensive emergencies be treated in the same way? Hipertens y Riesgo Vasc [Internet]. 2019 [cited 2020 Apr 17];36(3):119– 21. Available from: www.elsevier.es/hipertension 16. Viera AJ. Hypertension Update: Hypertensive Emergency and Asymptomatic Severe Hypertension. FP Essent. 2018 Jun 1;469:16–9. 17. Álvarez-Hernández L, Gallego-González D, Bañol-Betancur J, Martínez-Sánchez L, Rodríguez-Gázquez M, Marín-Cárdenas J, et al. Características clínicas y epidemiológicas de pacientes con crisis hipertensivas atendidos en el servicio de urgencias de una institución de alto nivel de complejidad, Medellín, Colombia 2014- 2015. Latinoam Hipertens. 2018;13(4). 18. Tarigan PB. Caracterización Epidemiológica De La Emergencia Hipertensiva Del Hospital Universitario De Neiva, Agosto 2011 - Octubre 2012. Vol. 53, Journal of Chemical Information and Modeling. 2013. 19. Acosta Miguel. Asociación Entre Comorbilidad Y Emergencia Hipertensiva En Un Servicio De Urgencia En Cartagena, Colombia. Repos. Unicartagena. 2010. 20. Cruz, E., Cadenas, M., Escobar, M., y González, A. (2010). Regulación ética en investigación con seres humanos en Colombia. Bogotá, Colombia: Iniciativa Panamericana en Bioética – PABI. 21. Grady, C., Eckstein, L., Berkman, B., Brock, D., Cook-Deegan, R., Fullerton, SM,
Greely, H., Hansson, MG, Hull, S., Kim, S., Lo, B., Pentz, R., Rodríguez, L., Weil, C., Wilfond, BS y Wendler, D. (2015). Consentimiento amplio para la investigación con muestras biológicas: Conclusiones del taller. La revista estadounidense de bioética: AJOB, 15 (9), 34–42. https://doi.org/10.1080/15265161.2015.1062162 22. Resolución 2378 del 2008 Fecha de consulta: 04-11-21 URL disponible en http://web.invima.gov.co/portal/documents/portal/documents/root/PORTAL%20IVC /BUENA%20PRA 23. Ortega Páez E, Ochoa Sangrador C, Molina Arias M. Regresión logística binaria simple. Evid Pediatr. 2022;18:11 24. Gian Paolo Rossi, Giacomo Rossitto, Chiarastella Maifredini, Agata Barchitta, Andrea Bettella, Raffaele Latella, Luisa Ruzza, Beatrice Sabini & Teresa M. Seccia (2021) Management of hypertensive emergencies: a practical approach, Blood Pressure, 30:4, 208-219, DOI: 10.1080/08037051.2021.1917983 25. Janke AT, McNaughton CD, Brody AM, Welch RD, Levy PD. Trends in the Incidence of Hypertensive Emergencies in US Emergency Departments From 2006 to 2013. J Am Heart Assoc. 2016 Dec 5;5(12):e004511. doi: 10.1161/JAHA.116.004511. PMID: 27919932; PMCID: PMC5210448 26. Zampaglione B, Pascale C, Marchisio M, et al. Hypertensive urgencies and emergencies. Prevalence and clinical presentation. Hypertension. 1996;27 (1):144–147. 27. Hannemann A, Friedrich N, Ludemann J, et al. Reference intervals for aldosterone, renin, and the aldosterone-to-renin ratio in the population-based study of health in pomerania
(SHIP-1). Horm Metab Res. 2010;42(06):392–399. 28. Shayne PH, Pitts SR. Severely increased blood pressure in the emergency department. Ann Emerg Med. 2003 Apr. 41(4):513-29. 29. Rhoades R, Pflanzer R. Human Physiology. 3rd ed. Fort Worth: Saunders College Publishing; 1996. 30. Salkic S, Batic-Mujanovic O, Ljuca F, et al. Clinical presentation of hypertensive crises in emergency medical services. Mater Sociomed 2014;26(1):12–6. 31. Pierin AM, Flórido CF, Santos J. Hypertensive crisis: clinical characteristics of patients with hypertensive urgency, emergency and pseudocrisis at a public emergency department. einstein (São Paulo). 2019;17(4):eAO4685. http://dx.doi.org/10.31744/einstein_journal/2019AO4685. 32. Nkoke C, Noubiap JJ, Dzudie A, M Jingi A, Njume D, Teuwafeu D, Aseneh J, Nkouonlack C, Menanga A, Kingue S. Epidemiology of hypertensive crisis in the Buea Regional Hospital, Cameroon. J Clin Hypertens (Greenwich). 2020 Nov;22(11):2105-2110. doi: 10.1111/jch.14035. Epub 2020 Sep 20. PMID: 32951311; PMCID: PMC8029769. 33. Arnéz Terrazas R., Rodríguez Quiroga S., Rocha J. Clinical and Epidemiological aspects of hipertensive crises in patients of the Worker Hospital Nro 2 - CNS Cochabamba. Gaceta Médica Boliviana 2008. 31(1):25-30. 34. Benenson I, Waldron FA, Jadotte YT, Dreker MP, Holly C. Risk factors for hypertensive crisis in adult patients: a systematic review. JBI Evid Synth. 2021 Feb 5;19(6):1292-
1327. doi: 10.11124/JBIES-20-00243. PMID: 33555818. 35. Álvarez-Hernández L., Gallego-González D., Bañol-Betancur J., Martínez-Sánchez L., Rodríguez-Gázquez M., Marín-Cárdenas J., Marín-Castro A., Jaramillo-Jaramillo L. Clinical and epidemiological characteristics of patients with hypertensive crises treated in the emergency service of a high level institution of complexity, Medellin, Colombia 2014-2015. Revista Latinoamericana de Hipertensión. Vol. 13 - No 4, 2018. 36. Cantone M, Lanza G, Puglisi V, Vinciguerra L, Mandelli J, Fisicaro F, Pennisi M, Bella R, Ciurleo R, Bramanti A. Hypertensive Crisis in Acute Cerebrovascular Diseases Presenting at the Emergency Department: A Narrative Review. Brain Sci. 2021 Jan 7;11(1):70. doi: 10.3390/brainsci11010070. PMID: 33430236; PMCID: PMC7825668. 37. Aggarwal M, Khan IA. Hypertensive crisis: hypertensive emergencies and urgencies. Cardiol Clin. 2006 Feb. 24(1):135-46. 38. Suneja M, Sanders ML. Hypertensive Emergency. Med Clin North Am. 2017 May;101(3):465-478. doi: 10.1016/j.mcna.2016.12.007. Epub 2017 Mar 2. PMID: 28372707. 39. Albaladejo Blanco C, et al. Crisis hipertensivas: seudocrisis, urgencias y emergencias. Hipertens Riesgo Vasc. 2014. http://dx.doi.org/10.1016/j.hipert.2014.04.001. 40. Brathwaite & Reif. Hypertensive Emergencies A Review of Common Presentations and Treatment Options. Cardiol Clin 37 (2019) 275–286. https://doi.org/10.1016/j.ccl.2019.04.003.
41. Peixoto AJ. Acute Severe Hypertension. N Engl J Med. 2019;381(19):1843. 42. Dhadke SV, Dhadke VN, Batra DS. Clinical profile of hypertensive emergencies in an intensive care unit. J Assoc Physicians India. 2017 May. 65 (5):18-22. 43. Wallbach M, Lach N, Stock J, et al. Direct assessment of adherence and drug interactions in patients with hypertensive crisis-A cross-sectional study in the Emergency Department. J Clin Hypertens (Greenwich) 2018. https://doi.org/10.1111/jch.13448. 44. Taylor DA. Hypertensive crisis: a review of pathophysiology and treatment. Crit Care Nurs Clin North Am 2015;27(4):439–47. 45. Brenner BM, Rector FC. Brenner & Rector’s the kidney. 10th edition. Philadelphia: Saunders Elsevier;2016. 46. Shah M, Patil S, Patel B, et al. Trends in hospitalization for hypertensive emergency, and relationship of end-organ damage with in-hospital mortality. Am J Hypertens 2017;30(7):700–6. 47. Andrade DO, Santos SPO, Pinhel MAS, et al. Effects of acute blood pressure elevation on biochemicalmetabolic parameters in individuals with hypertensive crisis. Clin Exp Hypertens 2017;39(6):553–61. 48. Saguner AM, Dur S, Perrig M, et al. Risk factors promoting hypertensive crises: evidence from a longitudinal study. Am J Hypertens 2010;23(7):775–80. 49. Xhignesse P., Krzesinski F., Krzesinski JM. Les crises hypertensives. Rev Med Liege 2018; 73:5-6:326-332.
50. Kaplan NM, Victor RG. Chapter 8: Hypertensive Crises. In: Kaplan's Clinical Hypertension, 11th Ed, Wolters Kluwer, 2010. p.263. 51. Elliott WJ. Clinical features in the management of selected hypertensive emergencies. Prog Cardiovasc Dis. 2006 Mar;48(5):316-25. 52. Ipek E, Oktay AA, Krim SR. Hypertensive crisis: an update on clinical approach and management. Curr Opin Cardiol. 2017 Jul. 32 (4):397-406. 53. Vadera R. Does antihypertensive drug therapy decrease morbidity or mortality in patients with a hypertensive emergency?. Ann Emerg Med. 2011 Jan. 57(1):64-5. 54. Pancioli AM. Hypertension management in neurologic emergencies. Ann Emerg Med. 2008 Mar. 51(3 Suppl):S24-7. 55. Greenland S. Modeling and variable selection in epidemiologic analysis. Am J Public Health. 1989; 79: 340-349.
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spelling Totora Rodríguez, Juan CamiloBeltrán Castro, Marvin Stiven2025-04-23T17:07:35Z2022-09-032025-04-23T17:07:35Z2022-10-19https://digitk.areandina.edu.co/handle/areandina/6294: ilustraciones, gráficos, tablas ; 28 cm.Este texto parece ser un estudio de investigación enfocado en crisis hipertensivas que se presentan en un servicio de urgencias en Bogotá, Colombia, durante 2020 y 2021. Se caracteriza clínicamente a los pacientes y se identifican factores asociados a estas crisis, diferenciando entre urgencias, emergencias y pseudocrisis hipertensivas. La metodología incluyó la revisión de historias clínicas, análisis estadísticos para evaluar asociaciones entre variables y se detallan los tratamientos utilizados. Los resultados destacan la prevalencia de hipertensión preexistente, la alta frecuencia de compromiso de órgano blanco cerebral en emergencias, y la asociación de diversos síntomas y antecedentes con los diferentes tipos de crisis.Tabla de contenido genérica Consideraciones generales.-- Pregunta de investigación.-- Objetivo de investigación.-- Justificación.-- Marco referencial.-- Metodología.-- Resultados.-- Conclusiones.-- Recomendaciones.-- Bibliografía.: ilustraciones, gráficos, tablas ; 28 cm.EspecializaciónEspecialista en Epidemiología128 Paginasapplication/pdfspaFundación Universitaria del AreandinacolombiaFacultad de Ciencias de la Salud y del DeporteEspecialización en EpidemiologíaTexto general de licencia/copyright EL AUTOR-ESTUDIANTE, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto, la obra es de su exclusiva autoría y tiene la titularidad sobre la misma. PARÁGRAFO: en caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL ESTUDIANTE-AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la Fundación Universitaria del Área Andina actúa como un tercero de buena fe.https://creativecommons.org/licenses/by-nc-nd/4.0/Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Caracterización Clínica E Identificación De Factores Asociados A Crisis Hipertensivas En El Servicio De Urgencias De La Unidad De Servicios De Salud Occidente De Kennedy De Bogotá, 2020 A 2021Trabajo de grado - EspecializaciónTextinfo:eu-repo/semantics/masterThesishttp://purl.org/redcol/resource_type/TMinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a851. Moya L, Moreno J, Lombo M, Guerrero C, Aristizábal D, Vera A, et al. Expert consensus on the clinical management of arterial hypertension in Colombia Colombian Society of Cardiology and Cardiovascular Surgery. Rev Colomb Cardiol [Internet]. 2018;25:4–26. Available from: https://doi.org/10.1016/j.rccar.2018.09.002 2. Mills KT, Bundy JD, Kelly TN, Reed JE, Kearney PM, Reynolds K. Global Disparities of Hypertension Prevalence and Control A Systematic Analysis of Population-Based Studies From 90 Countries. Circulation. 2016;441–50. 3. Mahfoud F, Böhm M, Bongarth CM, Bosch R, Schmieder RE, Schunkert H, et al. Comments on the guidelines (2018) of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH) on the management of arterial hypertension. Vol. 60, Internist. Springer Verlag; 2019. p. 424–30. 4. A global brief on hypertension | A global brief on Hyper tension [Internet]. 2013 [cited 2020 Apr 17]. Available from: www.who.int 5. Rosas-Peralta M, Borrayo-Sánchez G, Madrid-Miller A, Ramírez-Arias E, Pérez- Rodríguez G. Complicaciones cardiovasculares de la crisis hipertensiva. Rev Med Inst Mex Seguro Soc. 2016;54. 6. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint NationalCommittee (JNC 8). JAMA - J Am Med Assoc. 2014;311(5):507–20. 7. Cortés Fernández M del S, Segura J. Should all hypertensive emergencies be treated in the same way? Hipertens y Riesgo Vasc. 2019 Jul 1;36(3):119–21. 8. Brathwaite L, Reif M. Hypertensive Emergencies: A Review of Common Presentations and Treatment Options. Vol. 37, Cardiology Clinics. W.B. Saunders; 2019. p. 275–86. 9. Kallikazaros IE. Arterial Hypertension. Hell J Cardiol HJC • 413 Hell J Cardiol. 2013;54:413–6. 10. Hui R. Hypertension Drug Therapy. In Springer, Singapore; 2020. p. 149–268. 11. Albaladejo Blanco C, Sobrino Martínez J, Vázquez González S. Crisis hipertensivas: Seudocrisis, urgencias y emergencias. Hipertens y Riesgo Vasc [Internet]. 2014;31(4):132–42. Available from: http://dx.doi.org/10.1016/j.hipert.2014.04.001 12. Pierin AMG, Flórido CF, Santos J dos, Pierin AMG, Flórido CF, Santos J dos. Hypertensive crisis: clinical characteristics of patients with hypertensive urgency, emergency and pseudocrisis at a public emergency department. Einstein (São Paulo). 2019;17(4). 13. Paini A, Aggiusti C, Bertacchini F, Agabiti Rosei C, Maruelli G, Arnoldi C, et al. Definitions and Epidemiological Aspects of Hypertensive Urgencies and Emergencies. Vol. 25, High Blood Pressure and Cardiovascular Prevention. Springer International Publishing; 2018. p. 241–4. 14. Van den Born B-JH, Lip GYH, Brguljan-Hitij J, Cremer A, Segura J, Morales E, et al.ESC Council on hypertension position document on the management of hypertensive emergencies. Eur Hear J - Cardiovasc Pharmacother. 2019 Jan 1;5(1):37–46. 15. Cortés Fernández M, Segura J. Should all hypertensive emergencies be treated in the same way? Hipertens y Riesgo Vasc [Internet]. 2019 [cited 2020 Apr 17];36(3):119– 21. Available from: www.elsevier.es/hipertension 16. Viera AJ. Hypertension Update: Hypertensive Emergency and Asymptomatic Severe Hypertension. FP Essent. 2018 Jun 1;469:16–9. 17. Álvarez-Hernández L, Gallego-González D, Bañol-Betancur J, Martínez-Sánchez L, Rodríguez-Gázquez M, Marín-Cárdenas J, et al. Características clínicas y epidemiológicas de pacientes con crisis hipertensivas atendidos en el servicio de urgencias de una institución de alto nivel de complejidad, Medellín, Colombia 2014- 2015. Latinoam Hipertens. 2018;13(4). 18. Tarigan PB. Caracterización Epidemiológica De La Emergencia Hipertensiva Del Hospital Universitario De Neiva, Agosto 2011 - Octubre 2012. Vol. 53, Journal of Chemical Information and Modeling. 2013. 19. Acosta Miguel. Asociación Entre Comorbilidad Y Emergencia Hipertensiva En Un Servicio De Urgencia En Cartagena, Colombia. Repos. Unicartagena. 2010. 20. Cruz, E., Cadenas, M., Escobar, M., y González, A. (2010). Regulación ética en investigación con seres humanos en Colombia. Bogotá, Colombia: Iniciativa Panamericana en Bioética – PABI. 21. Grady, C., Eckstein, L., Berkman, B., Brock, D., Cook-Deegan, R., Fullerton, SM,Greely, H., Hansson, MG, Hull, S., Kim, S., Lo, B., Pentz, R., Rodríguez, L., Weil, C., Wilfond, BS y Wendler, D. (2015). Consentimiento amplio para la investigación con muestras biológicas: Conclusiones del taller. La revista estadounidense de bioética: AJOB, 15 (9), 34–42. https://doi.org/10.1080/15265161.2015.1062162 22. Resolución 2378 del 2008 Fecha de consulta: 04-11-21 URL disponible en http://web.invima.gov.co/portal/documents/portal/documents/root/PORTAL%20IVC /BUENA%20PRA 23. Ortega Páez E, Ochoa Sangrador C, Molina Arias M. Regresión logística binaria simple. 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