Determinación del modo de unión a la proteína dipeptidil peptidasa-IV (DPP-IV) de metabolitos reportados de especies de los géneros vismia, garcinia y neurolaena con potencial aplicación poli farmacológica para el tratamiento de la obesidad y la diabetes tipo 2.
The purpose of this study is to perform molecular docking of secondary metabolites present in the genera Vismia spp. (Hypericaceae), Garcinia spp. (Clusiaceae) and Neurolaena spp. (Asteraceae) to the Dipeptidyl Peptidase IV (DPP-IV) protein in order to identify potential drugs against diabetes Melli...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2022
- Institución:
- Universidad de América
- Repositorio:
- Lumieres
- Idioma:
- spa
- OAI Identifier:
- oai:repository.uamerica.edu.co:20.500.11839/8821
- Acceso en línea:
- https://hdl.handle.net/20.500.11839/8821
- Palabra clave:
- Fármacos
Metabolitos secundarios
Productos naturales
Drugs
Secondary metabolites
Natural products
Tesis y disertaciones académicas
- Rights
- License
- Atribución – No comercial
| Summary: | The purpose of this study is to perform molecular docking of secondary metabolites present in the genera Vismia spp. (Hypericaceae), Garcinia spp. (Clusiaceae) and Neurolaena spp. (Asteraceae) to the Dipeptidyl Peptidase IV (DPP-IV) protein in order to identify potential drugs against diabetes Mellitus type 2 and obesity which are diseases with high morbidity worldwide. Therefore, since 2014, the alliance (PRONADIAB) integrated by researchers from the Pontificia Universidad Javeriana and the Universidad Nacional de Colombia has proposed to search for natural alternatives, based on native plants from Chocó, for the treatment of these diseases. |
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