Diseño de un producto antibacterial para superficies procedente de extractos vegetales de Drimys granadensis L.f a nivel laboratorio

A surface disinfectant for domestic use, was developed from a partially polar fraction of the Andean Paramo specie: Drimys granadensis. The purpose of this project is to propose an organic alternative to the chemical synthetized products. To do so, the vegetal extract was fractionized with four incr...

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Autores:
Tipo de recurso:
Fecha de publicación:
2017
Institución:
Universidad de América
Repositorio:
Lumieres
Idioma:
spa
OAI Identifier:
oai:repository.uamerica.edu.co:20.500.11839/6560
Acceso en línea:
https://hdl.handle.net/20.500.11839/6560
Palabra clave:
Extracto vegetal
Propiedades antibacterianas
Fracción de acetona
Vegetable extract
Antibacterial properties
Acetone fraction
Tesis y disertaciones académicas
Rights
License
Atribución – No comercial
Description
Summary:A surface disinfectant for domestic use, was developed from a partially polar fraction of the Andean Paramo specie: Drimys granadensis. The purpose of this project is to propose an organic alternative to the chemical synthetized products. To do so, the vegetal extract was fractionized with four increasing polar solvents: hexane, chloroform, acetone and methanol. For each one of them, the antibacterial properties and the minimum inhibitory concentration were evaluated, in four bacterial strains: Staphylococus aureus, Staphylococus epidermis, Escherichia coli y Klebsiella pneumoniae, The results established that the acetone fraction presented the greater effectiveness, with a MIC of 15 mg/ml. According to the previous results, a phytochemical screening was developed through Thin-Layer Chromatography and detecting reagents, identifying Tannins and Cardiotonics, mostly.