Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage. We conducted a retrospective and descriptive observational study of patients with SLE...

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Autores:
Cañas Dávila, Carlos Alberto
Echeverri, Andrés Felipe
Tipo de recurso:
Article of investigation
Fecha de publicación:
2014
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/78485
Acceso en línea:
http://www.scopus.com/inward/record.url?eid=2-s2.0-84893658088&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78485
http://dx.doi.org/10.1155/2014/731806
Palabra clave:
Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/4.0/
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spelling Cañas Dávila, Carlos Albertof6cb08bb-4d92-453e-adb3-1b8dc5cd7368-1Echeverri, Andrés Felipe240fb85c-8da3-4767-a4b8-accb63f5c9e7-1Amsterdam de Lat: 52 21 00 N degrees minutes Lat: 52.3500 decimal degrees Long: 004 55 00 E degrees minutes Long: 4.9167 decimal degrees2015-10-13T21:06:03Z2015-10-13T21:06:03Z2014-01-010896-8411http://www.scopus.com/inward/record.url?eid=2-s2.0-84893658088&partnerID=tZOtx3y1http://hdl.handle.net/10906/78485http://dx.doi.org/10.1155/2014/731806instname:Universidad Icesireponame:Biblioteca Digitalrepourl:https://repository.icesi.edu.co/Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage. We conducted a retrospective and descriptive observational study of patients with SLE refractory to conventional treatment who were treated with rituximab (RTX) as remission induction therapy and maintenance. There was a significant reduction in the conventional immunosuppressive drug dose and the number of relapses of disease. RTX appeared to be effective and safe for the induction and maintenance of remission in patient with SLE refractory to conventional treatment. © 2014 Fabio Bonilla-Abadía et al.4 páginasDigitalapplication/pdfengElsevierÁmsterdamAutoimmune Diseases, Vo. 2014 - 201414EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus ErythematosusComunidad Universidad Icesi – Investigadores2014Lupus eritematoso sistémicoEnfermedad InflamatoriaEnfermedades autoinmuneshttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleORIGINALecheverri_rituximab_remission_2014.pdfecheverri_rituximab_remission_2014.pdfapplication/pdf1238438https://repository.icesi.edu.co/bitstreams/fcf86495-1a73-4538-9fb6-e8944b5a7667/download2bd59fd8be7aa7aeaadc9d84247af68fMD51THUMBNAILecheverri_rituximab_remission_2014.pdf.jpgecheverri_rituximab_remission_2014.pdf.jpgIM Thumbnailimage/jpeg11767https://repository.icesi.edu.co/bitstreams/14ed416b-b30f-4997-a40c-1dbe32a677fe/download6c77d5268202053e665495d7c9a24644MD5210906/78485oai:repository.icesi.edu.co:10906/784852025-08-17 22:02:06.631http://creativecommons.org/licenses/by-nc-nd/4.0/Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)open.accesshttps://repository.icesi.edu.coBiblioteca Digital - Universidad Icesiadquisicion-bib@listas.icesi.edu.co
dc.title.spa.fl_str_mv Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
spellingShingle Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
title_short Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_full Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_fullStr Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_full_unstemmed Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_sort Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
dc.creator.fl_str_mv Cañas Dávila, Carlos Alberto
Echeverri, Andrés Felipe
dc.contributor.author.spa.fl_str_mv Cañas Dávila, Carlos Alberto
Echeverri, Andrés Felipe
dc.subject.proposal.spa.fl_str_mv Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
topic Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
description Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage. We conducted a retrospective and descriptive observational study of patients with SLE refractory to conventional treatment who were treated with rituximab (RTX) as remission induction therapy and maintenance. There was a significant reduction in the conventional immunosuppressive drug dose and the number of relapses of disease. RTX appeared to be effective and safe for the induction and maintenance of remission in patient with SLE refractory to conventional treatment. © 2014 Fabio Bonilla-Abadía et al.
publishDate 2014
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http://hdl.handle.net/10906/78485
http://dx.doi.org/10.1155/2014/731806
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Autoimmune Diseases, Vo. 2014 - 2014
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dc.publisher.place.none.fl_str_mv Ámsterdam
publisher.none.fl_str_mv Elsevier
institution Universidad ICESI
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