Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19
In this work, the aim was to establish the relationship between the implementation of COVID-19 vaccines and the quality of the bibliographic material published to date. A search was conducted in the PubMed database for meta-analyses addressing the safety of implementing vaccines to prevent SARS-CoV-...
- Autores:
-
Erazo Diaz, Yefferson Esteban
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2024
- Institución:
- Universidad ICESI
- Repositorio:
- Repositorio ICESI
- Idioma:
- spa
- OAI Identifier:
- oai:repository.icesi.edu.co:10906/130368
- Acceso en línea:
- https://hdl.handle.net/10906/130368
https://biblioteca2.icesi.edu.co/cgi-olib/?oid=365034
- Palabra clave:
- Vacunas COVID-19
Efectos Adversos
Metaanálisis
Miocarditis
Parálisis De Bell
Trombosis
Trabajos de grado de Química Farmacéutica
COVID-19 Vaccines
Adverse Effects
Meta-analysis
Myocarditis
Bell's Palsy
Thrombosis
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/4.0/
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| dc.title.spa.fl_str_mv |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| dc.title.alternative.spa.fl_str_mv |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| title |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| spellingShingle |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 Vacunas COVID-19 Efectos Adversos Metaanálisis Miocarditis Parálisis De Bell Trombosis Trabajos de grado de Química Farmacéutica COVID-19 Vaccines Adverse Effects Meta-analysis Myocarditis Bell's Palsy Thrombosis |
| title_short |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| title_full |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| title_fullStr |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| title_full_unstemmed |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| title_sort |
Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19 |
| dc.creator.fl_str_mv |
Erazo Diaz, Yefferson Esteban |
| dc.contributor.advisor.none.fl_str_mv |
Marcillo Padilla, Karol Johana Acosta Santamaria, Angela Patricia |
| dc.contributor.author.none.fl_str_mv |
Erazo Diaz, Yefferson Esteban |
| dc.subject.proposal.spa.fl_str_mv |
Vacunas COVID-19 Efectos Adversos Metaanálisis Miocarditis Parálisis De Bell Trombosis Trabajos de grado de Química Farmacéutica |
| topic |
Vacunas COVID-19 Efectos Adversos Metaanálisis Miocarditis Parálisis De Bell Trombosis Trabajos de grado de Química Farmacéutica COVID-19 Vaccines Adverse Effects Meta-analysis Myocarditis Bell's Palsy Thrombosis |
| dc.subject.proposal.eng.fl_str_mv |
COVID-19 Vaccines Adverse Effects Meta-analysis Myocarditis Bell's Palsy Thrombosis |
| description |
In this work, the aim was to establish the relationship between the implementation of COVID-19 vaccines and the quality of the bibliographic material published to date. A search was conducted in the PubMed database for meta-analyses addressing the safety of implementing vaccines to prevent SARS-CoV-2 infection, and the bibliographic material deemed appropriate was selected. This material was qualified using the AMSTAR tool to ensure the use of the best quality bibliography for the study. In the end, it was found that COVID-19 vaccination may be related to the presence of local and systemic adverse effects, in addition to increasing the risk of myocarditis, Bell's palsy, and thrombosis. However, it is considered that the benefits of vaccination outweigh the potential risks associated with it. |
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2024 |
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2024-12-12 |
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2025-06-13T21:49:47Z |
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2025-06-13T21:49:47Z |
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bachelor thesis |
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spa |
| dc.relation.references.spa.fl_str_mv |
1. Medicina basada en la evidencia MBE ventajas. 2. Beltrán G, Ó. A. Revisiones Sistemáticas de La Literatura . (2005). 3. Boutron, isabelle . Chapter 7: Considering bias and conflicts of interest among the included studies. https://training.cochrane.org/handbook/current/chapter - 07 (2023). 4. Revised Cochrane Risk - of - B ias Tool for Randomized Trials (RoB 2) . (2019). 5. Pizarro, A. B., Carvajal, S. & Buitrago - López, A. Assessing the methodological quality of systematic reviews using the AMSTAR tool. Colombian Journal of Anesthesiology vol. 49 Preprint at https://doi.org/10.5554/22562087.e913 (2021). 6. Shea, B. J. et al. AMSTAR 2: A critical appraisal tool for systematic reviews that include randomised or non - randomised studies of healthcare interventions, or both. B MJ (Online) 358 , (2017). 7. Watanabe, A. et al. Assessment of Efficacy and Safety of mRNA COVID - 19 Vaccines in Children Aged 5 to 11 Years: A Systematic Review and Meta - analysis. JAMA Pediatr 177 , 384 – 394 (2023). 8. Katoto, P. D. M. C. et al. Safety of COVID - 19 Pfizer - BioNtech (BNT162b2) mRNA vaccinati on in adolescents aged 12 – 17 years: A systematic review and meta - analysis. Human Vaccines and Immunotherapeutics vol. 18 Preprint at https://doi.org/10.1080/21645515.2022.2144039 (2022). 9. R afati, A. et al. Association of SARS - CoV - 2 Vaccination or Infection with Bell Palsy: A Systematic Review and Meta - analysis. JAMA Otolaryngol Head Neck Surg 149 , 493 – 504 (2023). 10. Alami, A. et al. Risk of myocarditis and pericarditis in mRNA COVID - 19 - vacc inated and unvaccinated populations: a systematic review and meta - analysis. BMJ Open 13 , (2023). 11. Kim, A. Y. et al. Thrombosis patterns and clinical outcome of COVID - 19 vaccine - induced immune thrombotic thrombocytopenia: A Systematic Review and Meta - Analysis. International Journal of Infectious Diseases 119 , 130 – 139 (2022). |
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Universidad Icesi |
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Barberi de Ingeniería, Diseño y Ciencias Aplicadas |
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Química Farmacéutica |
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Marcillo Padilla, Karol JohanaAcosta Santamaria, Angela PatriciaErazo Diaz, Yefferson EstebanCali de Lat: 03 24 00 N degrees minutes Lat: 3.4000 decimal degrees Long: 076 30 00 W degrees minutes Long: -76.5000 decimal degrees.2025-06-13T21:49:47Z2025-06-13T21:49:47Z2024-12-12https://hdl.handle.net/10906/130368https://biblioteca2.icesi.edu.co/cgi-olib/?oid=365034instname:Universidad Icesireponame:Biblioteca Digitalrepourl:https://repository.icesi.edu.co/In this work, the aim was to establish the relationship between the implementation of COVID-19 vaccines and the quality of the bibliographic material published to date. A search was conducted in the PubMed database for meta-analyses addressing the safety of implementing vaccines to prevent SARS-CoV-2 infection, and the bibliographic material deemed appropriate was selected. This material was qualified using the AMSTAR tool to ensure the use of the best quality bibliography for the study. In the end, it was found that COVID-19 vaccination may be related to the presence of local and systemic adverse effects, in addition to increasing the risk of myocarditis, Bell's palsy, and thrombosis. However, it is considered that the benefits of vaccination outweigh the potential risks associated with it.En este trabajo se buscó establecer la relación entre la implementación de vacunas contra el COVID 19 y la calidad del material bibliográfico publicado hasta el momento. Se buscó en la base de datos PubMed metaanálisis que abordaran el tema de la seguridad de la implementación de vacunas para prevenir la infección de SARS-CoV-2 y se seleccionó el material bibliográfico que se consideró oportuno. Este material se calificó utilizando la herramienta AMSTAR para asegurar la utilización de la bibliografía de mejor calidad para el estudio. Al final, se encontró que la vacunación contra el COVID-19 puede estar relacionada con la presencia de efectos adversos locales y sistémicos, además de aumentar el riesgo de presentar miocarditis, parálisis de Bell y trombosis. Sin embargo, se considera que los beneficios de la vacunación son superiores a los riesgos que puedan estar relacionados con estaResumen . . . . . . 5 -- Introducción . . . . . 5 -- Metodología . . . . . 8 -- Búsqueda . . . . . 8 -- Identificación y calificación de los metaanálisis . . . . 8 -- Síntesis de la información encontrada . . . . 9 -- Resultados y discusión . . . . . 11 -- Conclusiones . . . . . 19 -- Anexo 1 . . . . . 21 -- Anexo 2 . . . . . 22 -- Anexo 3 . . . . . 23Trabajo de Grado para obtener el título del Programa de Química FarmacéuticaProfesional23 páginasDigitalapplication/pdfspaUniversidad IcesiBarberi de Ingeniería, Diseño y Ciencias AplicadasQuímica FarmacéuticaSantiago de caliEL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos Todo persona que consulte ya sea la biblioteca o en medio electróico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autohttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://purl.org/coar/access_right/c_abf2Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19Revisión de alcance de reportes de efectos adversos causados por vacunas contra el COVID - 19bachelor thesishttp://purl.org/coar/resource_type/c_7a1fTrabajo de gradoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/bachelorThesisTodo PúblicoVacunas COVID-19Efectos AdversosMetaanálisisMiocarditisParálisis De BellTrombosisTrabajos de grado de Química FarmacéuticaCOVID-19 VaccinesAdverse EffectsMeta-analysisMyocarditisBell's PalsyThrombosis1. Medicina basada en la evidencia MBE ventajas.2. Beltrán G, Ó. A. Revisiones Sistemáticas de La Literatura . (2005).3. Boutron, isabelle . Chapter 7: Considering bias and conflicts of interest among the included studies. https://training.cochrane.org/handbook/current/chapter - 07 (2023).4. Revised Cochrane Risk - of - B ias Tool for Randomized Trials (RoB 2) . (2019).5. Pizarro, A. B., Carvajal, S. & Buitrago - López, A. Assessing the methodological quality of systematic reviews using the AMSTAR tool. Colombian Journal of Anesthesiology vol. 49 Preprint at https://doi.org/10.5554/22562087.e913 (2021).6. Shea, B. J. et al. AMSTAR 2: A critical appraisal tool for systematic reviews that include randomised or non - randomised studies of healthcare interventions, or both. B MJ (Online) 358 , (2017).7. Watanabe, A. et al. Assessment of Efficacy and Safety of mRNA COVID - 19 Vaccines in Children Aged 5 to 11 Years: A Systematic Review and Meta - analysis. JAMA Pediatr 177 , 384 – 394 (2023).8. Katoto, P. D. M. C. et al. Safety of COVID - 19 Pfizer - BioNtech (BNT162b2) mRNA vaccinati on in adolescents aged 12 – 17 years: A systematic review and meta - analysis. Human Vaccines and Immunotherapeutics vol. 18 Preprint at https://doi.org/10.1080/21645515.2022.2144039 (2022).9. R afati, A. et al. Association of SARS - CoV - 2 Vaccination or Infection with Bell Palsy: A Systematic Review and Meta - analysis. JAMA Otolaryngol Head Neck Surg 149 , 493 – 504 (2023).10. Alami, A. et al. Risk of myocarditis and pericarditis in mRNA COVID - 19 - vacc inated and unvaccinated populations: a systematic review and meta - analysis. BMJ Open 13 , (2023).11. Kim, A. Y. et al. Thrombosis patterns and clinical outcome of COVID - 19 vaccine - induced immune thrombotic thrombocytopenia: A Systematic Review and Meta - Analysis. International Journal of Infectious Diseases 119 , 130 – 139 (2022).ORIGINALTG04016.pdfTG04016.pdfapplication/pdf565586https://repository.icesi.edu.co/bitstreams/cde6d8c3-e1c0-4778-95a6-0cdd39d5f26c/download879128e3af7a316dedd423bd4acd6f5cMD51LICENSElicense.txtlicense.txttext/plain1748https://repository.icesi.edu.co/bitstreams/cd7fae1e-d49e-4af3-9ab1-8a86add16a50/downloadbb9bdc0b3349e4284e09149f943790b4MD52CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8899https://repository.icesi.edu.co/bitstreams/2b1a5a36-6c5f-4c2a-85b4-9948632612a5/download3b6ce8e9e36c89875e8cf39962fe8920MD53THUMBNAILTG04016.pdf.jpgTG04016.pdf.jpgIM Thumbnailimage/jpeg2585https://repository.icesi.edu.co/bitstreams/3f5049ee-bb21-4103-a98a-5db80b189346/download8c2bd390a4ea816bb8901b1e1eae3bc2MD5410906/130368oai:repository.icesi.edu.co:10906/1303682025-06-18 11:01:12.585http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internationalopen.accesshttps://repository.icesi.edu.coBiblioteca Digital - Universidad Icesiadquisicion-bib@listas.icesi.edu.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 |